Gene Information

Name : Gobs_1933 (Gobs_1933)
Accession : YP_003409006.1
Strain : Geodermatophilus obscurus DSM 43160
Genome accession: NC_013757
Putative virulence/resistance : Virulence
Product : betaine-aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 2006573 - 2008102 bp
Length : 1530 bp
Strand : +
Note : PFAM: Aldehyde Dehydrogenase; KEGG: rha:RHA1_ro07077 aldehyde dehydrogenase (NAD+)

DNA sequence :
ATGTCCGAGCAGAGCGTCCTGAGCCCGCCCACCGGCGCGGCGTCCCCACCGACCCAGCTGATGCTGATCGGCGGGAACTG
GGTGGAGGCCGCCGACGGCGAGTGGCGTGAGATCACCAGCCCGGGTCACCGCGGCCACCTCCTCGCGCGCGTCCCGCGCG
GCAACGCCACGGACGTCGACCGCGCCGTGATCGCCGCGCGGGAGGCCTTCCCTGCTTGGCGCGACCAGCACTTCAAGGAG
CGCCAGCGGGTGCTGCTGAGGATCGCCGACGCCCTCGAGGGCCGCGCCGAGGAGCTCGCCCGGGTCACCGCCGCCGACAC
CGGGAACGCGCTGCGCACCCAGGCGCGGCCCGAGGCGGCGTTGCTGGTCGACCTGTTCCGCTACTTCGGCGGCGTGGCAG
GGGAGGTGAAGGGCACGACCCTGCCGGCCGGGGCGACGCAGCTGCAGTACACCCGGCAGGAGCCGCTGGGGGTGGTCGGC
GCGATCCTGCCGTGGAACTCGCCGCTGATGATCGCCGGCTTCAAGGTCCCGGCCGCACTGGCCGCGGGGAACACCATCGT
CCTCAAGGCCGCCGAGGACGCTCCGCTGTCCATCCTGCTGATGGCCGAGATCTGCGAGGAGTTCCTGCCGCCCGGCGTGC
TGAACGTGGTGACCGGTACCGGCCGGGCAGCGGGCAACGCCCTGGTCGAGCACCCCGGCGTGGACAAGATCTCCTTCACC
GGCTCCACCGAGGTCGGCCGGGGCATCGCCAGCAAGGCGGGGGAGCGGCTGGCCCACCTGTCCCTGGAGCTGGGCGGCAA
GAACCCGTCGATCGTGTTCCCCGGTGCGGTGACCGACGAGCTGATCGAGGGGCTGGTGCTGTCCTCGCGGATCAGCCGGC
AGGGCCAGAGCTGCACCGCCGGCTCGCGGCTGTACCTGCACCGCGACGTCCACGACGAGGTCCTCGCCCGGCTGGCGGAG
CGTCTGGGGGCGATGAAGGTCGGTGATCCGCTGGACGAGAGCAGCGACATCGGCTCGGTCATCAACGAGACCCAGTTCGA
CTCCATCACCGAGTACCTGCAGGACGGGCTGGCCAATCCCGCGCTGCACGTCGAGGTCGGTGGGTTGCCGCCGACCAGCG
GACCGCTGGCCGAGGGGTTCTTCCACGTGCCCACGTTGTTCTCCGGCGGCGACAACAGCTTCCGCCTCGCCCGCGAGGAG
ATCTTCGGGCCCGTGGTGGTCGCCATCGCCTGGGAGGACGTCGACGACGTCGTCCGCATGGCCAACGACACCGCGTACGG
GCTGGGTGCCTACGTCTGGAGCTCCGACATCAACCTGGCGATCACCACCGCGCACCGCCTCGAGGCCGGCTGGGTGCAGG
TCAACCAGGGCGGGGGACAGGTCGTCGGCCAGTCCTACGGCGGCTACAAGCAGAGCGGCATCGGCCGCGAGGTGTCCCTC
GAGGGCATGATCGCCGGCTTCACGCAGACCAAGCAGATCAACGTGCGCCTGGGCCACGGAGCGACCCCCGCGCCGCGCAC
GGGGCCCTGA

Protein sequence :
MSEQSVLSPPTGAASPPTQLMLIGGNWVEAADGEWREITSPGHRGHLLARVPRGNATDVDRAVIAAREAFPAWRDQHFKE
RQRVLLRIADALEGRAEELARVTAADTGNALRTQARPEAALLVDLFRYFGGVAGEVKGTTLPAGATQLQYTRQEPLGVVG
AILPWNSPLMIAGFKVPAALAAGNTIVLKAAEDAPLSILLMAEICEEFLPPGVLNVVTGTGRAAGNALVEHPGVDKISFT
GSTEVGRGIASKAGERLAHLSLELGGKNPSIVFPGAVTDELIEGLVLSSRISRQGQSCTAGSRLYLHRDVHDEVLARLAE
RLGAMKVGDPLDESSDIGSVINETQFDSITEYLQDGLANPALHVEVGGLPPTSGPLAEGFFHVPTLFSGGDNSFRLAREE
IFGPVVVAIAWEDVDDVVRMANDTAYGLGAYVWSSDINLAITTAHRLEAGWVQVNQGGGQVVGQSYGGYKQSGIGREVSL
EGMIAGFTQTKQINVRLGHGATPAPRTGP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-65 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-68 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-68 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-68 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Gobs_1933 YP_003409006.1 betaine-aldehyde dehydrogenase VFG0082 Protein 5e-66 42