Gene Information

Name : Acfer_1961 (Acfer_1961)
Accession : YP_003399627.1
Strain : Acidaminococcus fermentans DSM 20731
Genome accession: NC_013740
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2165865 - 2168408 bp
Length : 2544 bp
Strand : -
Note : KEGG: dae:Dtox_2007 ATP-dependent chaperone ClpB; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase- like; SMART: AAA ATPase

DNA sequence :
ATGCAGGCAGAACGCTTGAGTGATGAAGTGCGTGGATTGTTGGAAGCTGCCCAGCAGCAAGCCGTTATGAATTACAACCA
GGAACTGACCACCGTCCATCTGCTGTCCGCCATGTGCAGCCAGCCGGACGGGTTCTTCAAGTTTGTGCTGAAGAGCCTGA
ACGTGGATGAGGCCCAGTTCAGCCGGGAAGTGGACCGGCTGCTGAAACAGATCCCCTCTGTGAAGGGGTCCGACCAGATG
AGCATGAGCACGGGGCTGGCCCGGGTGTTCGCCCTGGCGGAAAAGGCTGCCGGCCAGAACCCGGTGACCGCATCCCATCT
GCTGGCCGCTCTCTGTGAGGACGGGGATACGGAAGTGGTGAACCTGTGCAAAAAGTACGGGATCACCCGCAGTGCCATCC
GGGGTCTGATCGACAAATATGAAAACAACGGGGATGCGGACGAAAACCGCAAGACCCTGGAGAAATTCGGCCAGGACCTG
ACCCAGAAAGCCCGGGATGGGAAACTGGATCCGGTGATTGGCCGTGACGATGAAATCCGTCGGACCATCGAGATCCTGTC
CCGCCGGAAAAAGAACAACCCGGTGCTGATCGGTGAACCCGGCGTGGGCAAAACCGCCATTGTGGAAGGTCTTGCCCGCC
GTATCGTGGCCGGAGATGTGCCGGAATCCCTGAAGAACAAGACCCTGTATGCCCTGGACCTGGCGTCTTTGGTGGCCGGG
GCCAAGTACAGAGGGGAATTCGAGGAACGGCTGAAGAAAGTCCTGAAGATCGTGTCCGATTCCGCCGGTCAGATCATCAT
GTTCATCGATGAACTGCACACGGTGGTGGGGGCCGGGGCTTCCGAAGGCTCCATGGATGCCGGGAACATCCTGAAACCCA
TGCTGGCCAGAGGGGAACTCCGGTGCATCGGTGCCACCACCCTGAAGGAATACCGGAAGTACATTGAAAAGGATTCTGCT
CTGGAACGGCGTTTCCAGCCGGTGCTGGTGAAGGAGCCCAGTGTGGAGGACACCATTTCCATCCTGAGAGGGCTGAAGGA
ACGGTATGAAGTCCATCATGGGGTGCGGATCAAGGATTCCGCCCTGGTGGCGGCCGCAACCCTGAGCAACCGGTACATCA
ACGACCGGTTCCTGCCGGACAAGGCCATCGACCTGGTGGATGAAGCAGCTGCCCGTCTGCGGGTGGAAATCGATTCCATG
CCCACGGAACTGGATGAAAGCCGCCGGCGGATGCTCCAGCTCCAGATCGAGGAACAGGCCCTGTCCAAGGAAGAGGACGA
TGCTTCCAAGGCCCGTCTGGAAAAAATCAAAGAGGAACTGGCCAAGCTGAAGAGCGAGAACGACAAGCTCATGGACCAGT
GGAAGGCCGAAAAGGGCGGCATTGCCAAGATCCGTCAGGTGAAGAAGGATATGGACAATGTGAAGAAGGAAATGGAAGAA
GCGGAGCGGTCCTATGACCTGAACCGTCTGGCAGAACTGAAGTACGGCAAGTTGCCGGAACTCCAGAAACAGCTGGCGGC
CCTGGAAAAAGAGGAACATTCCGACAAGCGCCTGCTGAAGGAAGAAGTGGACGAGGATGATATCGCCAAGGTGGTCAGCA
CCTGGACGGGGATCCCTGTGAACCGTCTGATGGAGGGGGAAAAGAAGAAACTGGCCCATCTGCCGGAAATCCTCCACAAA
CGGGTGATCGGCCAGGACGAAGCGGTGGAAGCCGTCAGCGAAGCCGTCATCCGGGCCCGGGCCGGGATCAAGGATCCCAA
CAAGCCCATTGGCTCCTTCATCTTCCTGGGGCCCACCGGTGTGGGCAAGACCGAACTGGCCAAAGCCCTGGCAGAAGTGC
TGTTCAATGATGAAAAGAGCATCATCCGGATCGATATGAGTGAATACATGGAGAAACATACGGTGTCCCGTCTGATCGGT
GCCCCTCCTGGCTATGTGGGCTATGAAGAGGGCGGCCAGCTGACGGAAGCCGTGCGGCGCCATCCGTATTCCGTGATCCT
GTTCGATGAAATCGAAAAGGCTCACCCGGATGTGTTCAACGTGCTGCTGCAGGTGCTGGACGACGGCCGTCTGACCGACG
GTCAGGGCCGGATGGTGGATTTCAAGAACACCCTGATCATCATGACCAGCAACCTGGGGTCCCATGAGATTATGGAAAAG
AAGGGGGCCATCAGCAAGGACGAAGTCCGGAGCATGCTGATGAAGTTCTTCCGGCCGGAATTCCTGAACCGGGTGGACGA
CATTGTGGTGTTCAAACCCCTGCAGGAAGAACAGCTGAAGGACATTGTACGGCTGATTCTGAACCATCTGGGCAGCCGGC
TGCACAGCCAGCTGGAACTGACCCTGACGGCCACCGACGACGCCATTGCCTACCTGGCCAAAGCCGGGTTCGACCCTGCC
TTCGGGGCCCGTCCCCTGAAGAGACTGATTGTCCACACAGTGGAAACCGTGGTGAGCAACAAGATCGTCCGGGGCGAGAT
CCAGAGAGGGGATCATATCGAAGTGGTATTCAAGGACGGGAACATCGATGTGGTGAAGAAATAA

Protein sequence :
MQAERLSDEVRGLLEAAQQQAVMNYNQELTTVHLLSAMCSQPDGFFKFVLKSLNVDEAQFSREVDRLLKQIPSVKGSDQM
SMSTGLARVFALAEKAAGQNPVTASHLLAALCEDGDTEVVNLCKKYGITRSAIRGLIDKYENNGDADENRKTLEKFGQDL
TQKARDGKLDPVIGRDDEIRRTIEILSRRKKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLKNKTLYALDLASLVAG
AKYRGEFEERLKKVLKIVSDSAGQIIMFIDELHTVVGAGASEGSMDAGNILKPMLARGELRCIGATTLKEYRKYIEKDSA
LERRFQPVLVKEPSVEDTISILRGLKERYEVHHGVRIKDSALVAAATLSNRYINDRFLPDKAIDLVDEAAARLRVEIDSM
PTELDESRRRMLQLQIEEQALSKEEDDASKARLEKIKEELAKLKSENDKLMDQWKAEKGGIAKIRQVKKDMDNVKKEMEE
AERSYDLNRLAELKYGKLPELQKQLAALEKEEHSDKRLLKEEVDEDDIAKVVSTWTGIPVNRLMEGEKKKLAHLPEILHK
RVIGQDEAVEAVSEAVIRARAGIKDPNKPIGSFIFLGPTGVGKTELAKALAEVLFNDEKSIIRIDMSEYMEKHTVSRLIG
APPGYVGYEEGGQLTEAVRRHPYSVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRMVDFKNTLIIMTSNLGSHEIMEK
KGAISKDEVRSMLMKFFRPEFLNRVDDIVVFKPLQEEQLKDIVRLILNHLGSRLHSQLELTLTATDDAIAYLAKAGFDPA
FGARPLKRLIVHTVETVVSNKIVRGEIQRGDHIEVVFKDGNIDVVKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-104 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Acfer_1961 YP_003399627.1 ATP-dependent chaperone ClpB VFG2076 Protein 7e-124 45
Acfer_1961 YP_003399627.1 ATP-dependent chaperone ClpB VFG2084 Protein 1e-119 44