Gene Information

Name : Acfer_1763 (Acfer_1763)
Accession : YP_003399434.1
Strain : Acidaminococcus fermentans DSM 20731
Genome accession: NC_013740
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1945743 - 1946882 bp
Length : 1140 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: cth:Cthe_2799 cystathionine gamma-synthase

DNA sequence :
ATGAAATTCACTACGGCCTGTATCCACGGAGGCGGCCCCAACGATGCCACAGGGGCTGTTTCTCCGGCTCTGTATCTCAC
ATCCACCTTTGCCCATCCTGGACTGGGACAGTCCACCGGCTGGGCCTATACCCGGGAATCCAACCCCACCCACGCCAGAC
TGGAAAAAGTCCTGTCCACCCTGGAAGGGGGCACCGATGCCCTGTGCTTTTCCTCCGGCATGGCAGCCATCGATGCGGTG
ATGCGGCTTTTTGCCCCGGGGGATCACCTTATCACCGGCTTCGACCTGTACGGCGGGTCCTTCCGGCTGTTCCGGACCAC
CTATGAACCCCTGGGGCTTACCTTCACCCCCGTCCACACCAGCGACCTGAAGGCGGTGGAAAAAGCCATCACCCCGGCCA
CCCGGGCCATCTACCTGGAAACCCCCACCAATCCCACCATGGAGATCACCGATCTGGAAGCCCTCAGCGACCTGGCCCAC
CGGCACCAGCTGCTGGTAATCGTGGACAACACCTTCCTGTCCCCTTGCTTCCAGCGGCCCCTGACCCTGGGTGCGGACAT
CGTGGTCCACAGCGGCACCAAGTACCTGGCCGGCCACAACGATCTGCTGGCCGGTTTCGCCATCAGCCGGGAAGAGGAAG
TGGCAGCCCGTCTCCGGACCATCTACAAGACCACCGGAACCGTGCTCAGCGTCTTTGACGCCTGGCTCATGCTCCGGAGC
CTGAAGACCCTGCCGGTGCGGATGAAGCAGCACCAGGAAAACGCCCTGTACCTGGCCCGGTGGCTGGAACAGCAGCCCCT
GGTGGAAAAGGTGCTGTATCCCGGGCTGCCGGACCATCCGGGCTATGCCATCCAGAAAAAACAGGCCAACGGGTTCGGCG
GGATGATTTCCTTCTATGTGAAATCCCCGGAAGCCGCCAAGACCATCCTGGAAAAGATCCGGCTGATCCAGTTCGCCGAA
AGCCTGGGAGGCACCGAAAGCCTGCTCACCTATCCCATTACCCAGACCCATGCGGACCTGACCCCGGAAGAAGCGGAAGA
AAAGGGCATCACCCACACCCTGCTCCGGTTCTCCGTAGGACTGGAAGACAAGGAAGACCTGCGGGACGACCTGGCCCAGG
CGTTCCGCCAGTGCAAATAA

Protein sequence :
MKFTTACIHGGGPNDATGAVSPALYLTSTFAHPGLGQSTGWAYTRESNPTHARLEKVLSTLEGGTDALCFSSGMAAIDAV
MRLFAPGDHLITGFDLYGGSFRLFRTTYEPLGLTFTPVHTSDLKAVEKAITPATRAIYLETPTNPTMEITDLEALSDLAH
RHQLLVIVDNTFLSPCFQRPLTLGADIVVHSGTKYLAGHNDLLAGFAISREEEVAARLRTIYKTTGTVLSVFDAWLMLRS
LKTLPVRMKQHQENALYLARWLEQQPLVEKVLYPGLPDHPGYAIQKKQANGFGGMISFYVKSPEAAKTILEKIRLIQFAE
SLGGTESLLTYPITQTHADLTPEEAEEKGITHTLLRFSVGLEDKEDLRDDLAQAFRQCK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-57 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-69 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Acfer_1763 YP_003399434.1 cystathionine gamma-synthase BAC0207 Protein 3e-63 43