Gene Information

Name : Acfer_0159 (Acfer_0159)
Accession : YP_003397882.1
Strain : Acidaminococcus fermentans DSM 20731
Genome accession: NC_013740
Putative virulence/resistance : Virulence
Product : two component transcriptional regulator, winged helix family
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 183117 - 183803 bp
Length : 687 bp
Strand : -
Note : PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: chy:CHY_0092 DNA-binding response regulator

DNA sequence :
ATGGAAAAAATCCTGATCGTGGAAGATGACCTGGATATTGCCGAACTGGAACGGGATTATCTGGAAGCCAACGGGTTTGC
GGTGGCCATTGCCGGAGACGGCCTGGCCGGAGAAAAGGCGGCCCTGGATGAAAAAGTGGACCTGGTGCTCCTGGACATTA
TGCTGCCTGGGATGGACGGATTCCAGGTCTGCCGGCGGATCCGGGAAAAGCGGAACATCCCCATCCTGCTGGTATCCGCC
CGACAGGAGGACGTGGACAAAATCCGGGGTCTGGGTCTGGGAGCCGATGACTACATCGTCAAGCCCTTCAGCCCCGGGGA
ACTGGTAGCCCGGGTCAAGGCCCATCTCCAGCGGTACCGGCAGCTCACCGGGCAGCATTCCGGGGACCAGCTGCTCCGGC
GGAAAGACCTGACCATCGACCGGAAAGGCCATCATGTGTACCTGAAGGGAAAAGAGATCGCCATGCCCAACAAGGAATTT
TCTCTGCTCCTGTTCCTTGCCGAAAACCCCGGTGTGGTCTTCAGCAAGGAAACCCTGTTCGAACGGATCTGGGGAGAGGA
TTCCCTGGGAGATACCGCCACCGTATCCGTCCACGTGAACCGGATCCGGGAAAAGATCGAACCCTCCACCGCCAAACCGG
AATACATTGAAACCGTCTGGGGCGTGGGGTACCGGTTCCGGAAATGA

Protein sequence :
MEKILIVEDDLDIAELERDYLEANGFAVAIAGDGLAGEKAALDEKVDLVLLDIMLPGMDGFQVCRRIREKRNIPILLVSA
RQEDVDKIRGLGLGADDYIVKPFSPGELVARVKAHLQRYRQLTGQHSGDQLLRRKDLTIDRKGHHVYLKGKEIAMPNKEF
SLLLFLAENPGVVFSKETLFERIWGEDSLGDTATVSVHVNRIREKIEPSTAKPEYIETVWGVGYRFRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 1e-39 43
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 3e-39 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family AM180355.1.gene1830. Protein 4e-48 45
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family DQ212986.1.gene4.p01 Protein 8e-47 45
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family HE999704.1.gene2815. Protein 2e-44 45
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family AF155139.2.orf0.gene Protein 7e-46 45
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family AF130997.1.orf0.gene Protein 3e-44 44
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family AF162694.1.orf4.gene Protein 6e-45 44
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family EU250284.1.orf4.gene Protein 3e-46 43
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family NC_014475.1.orf0.gen Protein 2e-48 42
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family NC_005054.2598277.p0 Protein 2e-48 42
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family NC_012469.1.7685629. Protein 5e-36 42
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family CP001581.1.gene280.p Protein 2e-38 42
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family AE000516.2.gene3505. Protein 7e-37 42
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family BAC0125 Protein 3e-31 41
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family AE016830.1.gene1681. Protein 5e-41 41
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family FJ349556.1.orf0.gene Protein 1e-42 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family VFG1702 Protein 4e-40 43
Acfer_0159 YP_003397882.1 two component transcriptional regulator, winged helix family VFG1563 Protein 2e-39 42