Gene Information

Name : Acfer_1549 (Acfer_1549)
Accession : YP_003399222.1
Strain : Acidaminococcus fermentans DSM 20731
Genome accession: NC_013740
Putative virulence/resistance : Resistance
Product : arsenite-activated ATPase ArsA
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0003
EC number : 3.6.3.16
Position : 1708071 - 1709804 bp
Length : 1734 bp
Strand : +
Note : KEGG: dhd:Dhaf_1189 arsenite-activated ATPase ArsA; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase

DNA sequence :
ATGGAACTGTATGATCCTTTTGCCGCCATCCGCACCCAGTATGTGTTCTTTACCGGCAAAGGCGGTGTGGGTAAGACCTC
CACAGCCTGTGCCACCGCCGTGGCTCTGGCCGACGCCGGACAGAAAGTGCTGCTGGTCAGCACGGACCCGGCCTCCAATC
TCCAGGACATCTTTTCTCTGGAACTGAAAGAAAAACCCACTCCCATTCCCGGTGTCCCCGGGCTGGAAGCGGCCAACCTG
GATCCGGTCAAGGCCGCTGCCGCCTACCGGGAAAGCGTGGTGGGTCCCTATCGAGGCATTCTGCCGGAAGCCGCCCTGCG
GAACATGGAAGAACAGCTGTCCGGTTCCTGCACCATCGAAATCGCTGCTTTCAACGCCTTTACGGATTTCCTCACAGATC
CGGAAACGGCCACAGCTTATGATAAGATCATTTTCGATACAGCTCCCACCGGCCATACCCTGCGGATGCTCCAGCTGCCT
TCTGCCTGGAGCCAGTTTATCAGCACCAGTACCCACGGAGCCTCCTGTCTGGGTCAACTGTCCGGCCTGGAAAGCCGGAA
GGCCCTGTACCGGCAGGCTGTAGAAACGCTGGCGGATCCTGGCCGGACCACCCTGCTTCTGGTGGCCCGTCCTGACCGGC
CTCCGCTTTTGGAAGCGGACCGGGCATCCCGGGAACTGGCCAAACTGGGCATCGGCAACCAGCAGCTGATCATCAACGGG
CTGCTGGAAAAAACCGATGATCCGGTCACCAAAGAACTTTTTGCCAAACAGCAGATGGCTCTGGCAGAAATGTCCCAGGG
GCTGAAAATCCTGCCATCCTGGCAGATTCCCTTCCGGAGCTACAATGTGACCGGCCTGGACCATGTACGGGCTCTCCTGA
AAGGGGAAGTGGCCCCAGTCGCCGGACGGGAACAACAGGCTCCCGTCTACACCCTCCAGGAGGTGGCGGAAGATCTGGAG
CGGAATCATCGGAAGGTCATCTTCACCATGGGCAAAGGCGGCGTGGGAAAAACCACTGTAGCGGCCTCCCTGGCTCTCCG
TCTGGCCCAAAAGGGACACCAGGTACTGCTCACCACCACCGACCCGGCCGGCCATCTCCAGGAAATCCTGGATCAGACGG
ACCGGCTCCAGCTGTGCCAGATCGATGAGCAGGCTGAACTCCGCCGCTACCAGAAGGAAGTCCTGGACCAGGCCCGGAAA
AATGGCCTGAAAGAAGGAGATCTGGCTTACATCGAAGAAGACCTCCGTTCCCCCTGCACCCAGGAAATCGCCGTGTTCCG
GGCATTTGCAGAAATCGTGGCCCGGTCCGGGGACCGGATTGTCATCATCGACACTGCCCCAACCGGCCATACCCTGCTGC
TCCTGGAATCCACAGAAAACTACGACCGGGAGATCCGCCGGACCCGGGGTGCTGTTCCCCCTGCCGTCCAGCAGCTACTG
CCCCGGCTGAAAGGGCCGGAAACGGAAGTGGTGATCGTCACCCTGCCAGAAGCCACTCCTGTGTATGAAGCCCTGCGTCT
GGAAGCAGATTTGAAACGGACCCGGCTCTACAGCCGCTGGTGGATCATCAACCGGTGCTTCAGCCAGACTGCCGCCCAAA
GCCCTCTGCTAAAGGCCAAAGCGGACCGGGAAATCCCCTGGATCAACCAGGTGGCAGCCCACGCCAGCGGCTGTGCGGCA
GTGATTCCCTGGAAACAGGCAGAAATCAAAGGAAAGGTGCTGGAAACATTATGA

Protein sequence :
MELYDPFAAIRTQYVFFTGKGGVGKTSTACATAVALADAGQKVLLVSTDPASNLQDIFSLELKEKPTPIPGVPGLEAANL
DPVKAAAAYRESVVGPYRGILPEAALRNMEEQLSGSCTIEIAAFNAFTDFLTDPETATAYDKIIFDTAPTGHTLRMLQLP
SAWSQFISTSTHGASCLGQLSGLESRKALYRQAVETLADPGRTTLLLVARPDRPPLLEADRASRELAKLGIGNQQLIING
LLEKTDDPVTKELFAKQQMALAEMSQGLKILPSWQIPFRSYNVTGLDHVRALLKGEVAPVAGREQQAPVYTLQEVAEDLE
RNHRKVIFTMGKGGVGKTTVAASLALRLAQKGHQVLLTTTDPAGHLQEILDQTDRLQLCQIDEQAELRRYQKEVLDQARK
NGLKEGDLAYIEEDLRSPCTQEIAVFRAFAEIVARSGDRIVIIDTAPTGHTLLLLESTENYDREIRRTRGAVPPAVQQLL
PRLKGPETEVVIVTLPEATPVYEALRLEADLKRTRLYSRWWIINRCFSQTAAQSPLLKAKADREIPWINQVAAHASGCAA
VIPWKQAEIKGKVLETL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsA2 YP_001007632.1 arsenical pump-driving ATPase Not tested YAPI Protein 1e-107 47
SH0111 YP_252026.1 arsenical pump-driving ATPase Not tested SCCmec Protein 3e-105 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Acfer_1549 YP_003399222.1 arsenite-activated ATPase ArsA BAC0572 Protein 7e-105 47
Acfer_1549 YP_003399222.1 arsenite-activated ATPase ArsA BAC0571 Protein 4e-106 46
Acfer_1549 YP_003399222.1 arsenite-activated ATPase ArsA BAC0030 Protein 1e-101 45