Gene Information

Name : Cwoe_4862 (Cwoe_4862)
Accession : YP_003396649.1
Strain : Conexibacter woesei DSM 14684
Genome accession: NC_013739
Putative virulence/resistance : Virulence
Product : betaine-aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 5186356 - 5187852 bp
Length : 1497 bp
Strand : -
Note : PFAM: aldehyde dehydrogenase; KEGG: tmz:Tmz1t_0766 aldehyde dehydrogenase (NAD(+))

DNA sequence :
ATGGCTGTCGCCGTCCCCATCGGTGAAGCGACCCGCCGTTTCACGTCCGAGCCGCGCAAGCTGCTGATCGGCGGTCAGTG
GCGGGAGTCCGTCAGCGGCAAGACGTTCGACACCTACGACCCGGCGACCGGCGCGGTGCTCGCGACCGTCGCGGAGGGCG
ACGCGCAGGACGTCGAGCTGGCAGTCGCGGCCGCTCGCAGAGCGCTGGAGGACGGGCCGTGGTCCCGCCTGAACCCATCC
GAGCGTGGGCGGATCGTCCACCGCGTCGGCGACCTGATCATGGAGAACGCGGACGAGCTGGCGGAGCTGGAGACGCTCGA
CAACGGCAAGCCGAAGGCGGTCGCCGCGGCGGCCGACGTCCCGCTCGCGGCTGACCTCTTCTGGTACATGGCCGGATGGG
CGACGAAGCTCAACGGCGGCACGATCAACCCGTCGGTGCCGTACATGCCCGGCGCTGAGTTCCATGCCTACACGTTGCGC
GAGCCGGTCGGCGTCGTCGGCCAGATCATCCCGTGGAACTTCCCGCTGCTGATGGCGGCGTGGAAGCTCGGCCCGGCGCT
CGCGACCGGCTGCACCGTCGTGCTGAAGCCGGCCGAGCAGACGCCGCTGAGCGCGCTGCGGCTCGGCGAGCTGCTGCTGG
AGGCGGGCGTGCCCGACGGCGTCGTCAACGTGATCCCCGGCTACGGCGAGACGGCCGGCGCCGCGCTCGCCGCGCACGAG
GGCGTCGACAAGGTCGCCTTCACCGGCTCGACCGAGGTCGGCAAGCTGATCGCGCAGACCGCGACCGGCAACCTCAAGCG
CGTCTCGCTGGAGCTCGGCGGCAAGTCGCCGAACGTCGTCTTCTCCGACGCCGACGTCGACGCCGCGATCGCCGGCGCCG
CGCAGGGGATCTTCTTCAACCAGGGCGAGGTCTGCTCCGCCGGCTCGCGCCTGTACGTGCAGGAGGACCAGTTCGACCGC
GTCGTCGAGGGGATCACGAGCGCGGCGAAGTCGATCAGAGTCGGTCACGGCCTCGACCCGACGACGGAGATGGGCCCGCT
CGTCTCCCAGGAGCAGTTCGACCGCGTCACCGGCTACCTCGCGAAGGGCGCCGCCGAGGGCAACCGCGCGACCGCCGGCG
GCTCCGCGATCGACGGCGACGGCTGGTTCGTCCAGCCGACTGTGCTGGTCGACGCGACGCCCGAGCACACGATCGTGCGC
GAGGAGGTCTTCGGGCCGGTGATCGCCGCGATGCCGTTCAGCGACGTCGACGACCTCGCGCGCCAGGCGAACGACTCCCA
CTACGGCCTCGCCGCCGGCGTCTGGACGCGCGACGTCTCCAAGGCGCACAAGCTGGCGAAGCGGATCAAGGCCGGCACCG
TGCACGTCAACAGCTACCACGTGTTCAGCGCCGAGCTGCCGTTCGGCGGCTACAAGCAGTCCGGCTGGGGCCGCGAGATG
GGCGAGGAAGTGCTCAACAACTACCTCGAGACGAAGTCGGTCATCGTCGCGCTGTAG

Protein sequence :
MAVAVPIGEATRRFTSEPRKLLIGGQWRESVSGKTFDTYDPATGAVLATVAEGDAQDVELAVAAARRALEDGPWSRLNPS
ERGRIVHRVGDLIMENADELAELETLDNGKPKAVAAAADVPLAADLFWYMAGWATKLNGGTINPSVPYMPGAEFHAYTLR
EPVGVVGQIIPWNFPLLMAAWKLGPALATGCTVVLKPAEQTPLSALRLGELLLEAGVPDGVVNVIPGYGETAGAALAAHE
GVDKVAFTGSTEVGKLIAQTATGNLKRVSLELGGKSPNVVFSDADVDAAIAGAAQGIFFNQGEVCSAGSRLYVQEDQFDR
VVEGITSAAKSIRVGHGLDPTTEMGPLVSQEQFDRVTGYLAKGAAEGNRATAGGSAIDGDGWFVQPTVLVDATPEHTIVR
EEVFGPVIAAMPFSDVDDLARQANDSHYGLAAGVWTRDVSKAHKLAKRIKAGTVHVNSYHVFSAELPFGGYKQSGWGREM
GEEVLNNYLETKSVIVAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-75 47
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-76 46
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-76 46
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-76 46
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-76 46
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-74 45
hpaE AAO17179.1 HpaE Not tested tcd island Protein 6e-65 43
unnamed AAK01506.1 putative aldehyde dehydrogenase Not tested PAGI-1 Protein 4e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cwoe_4862 YP_003396649.1 betaine-aldehyde dehydrogenase VFG0082 Protein 3e-74 45