Gene Information

Name : Slin_6258 (Slin_6258)
Accession : YP_003391016.1
Strain : Spirosoma linguale DSM 74
Genome accession: NC_013730
Putative virulence/resistance : Virulence
Product : N-6 DNA methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 7591096 - 7593459 bp
Length : 2364 bp
Strand : +
Note : PFAM: N-6 DNA methylase; KEGG: vcm:VCM66_1707 DNA methylase HsdM

DNA sequence :
ATGAATCACCAATCCCATAATAAATTAGTCTCCTTTATCTGGTCCATTGCCGATGATTGCCTGCGCGACGTGTACGTGCG
GGGTAAGTATCGCGACGTTATCTTACCGATGGTTGTCTTGCGCCGACTGGATGCGCTGCTCGAACCGGGTAAAGATGAGG
TGATGGAAGAAGTTCGGTTTCAGCGCGAAGAGGCCGGTTTTACCGAACTGGATGTCAATGGCCTACAGGCGGCATCGGGC
TACGTTTTTTATAATACCAGTGTCTGGACGCTGCAAAAGCTGCACGATACAGCCACCAATAACCAGCAATTATTGGAAGC
TAACTTCACGGATTACCTCGACGGCTTCAGCGATAACGTCAAGGAGATTATCCGCAAGTTCAACCTGAAGAGCCAGGTGA
AGCACATGGCCAATAAGGATGTGCTGCTCGACGTGCTGGAGAAGTTCACCTCACCCACGATCAACCTGACCCCTTTTGAA
AAACTGGACCCCGAAGGACGTAAACTACCGGCCCTGTCGAACTTGGGCATGGGCTACGTGTTTGAGGAGCTGATCCGTAA
GTTCAACGAAGAGAACAACGAGGAAGCCGGAGAACACTTTACGCCCCGTGAAGTCATCGACCTAATGACCCACGTCATTT
TTGAGCCCATTAAAGACCGGCTGCCACCCGTTATGACCATTTATGACCCGGCCTGCGGTTCGGGTGGGATGCTGACCGAA
TCCCAGAACTTCATAAAAGATGAAGATGGGCTTATTCGGGCCAAAGGCGATGTGTATCTCTTTGGTAAGGAGATCAACGA
CGAGACCTACGCCATCTGTAAGTCGGATATGATGATTAAGGGCAATGATCCCGAAAACATCAAAAACGGCTCTACGCTCT
CGACCGACGAGTTTGCTGGAAAGCAGTTCGATTTTATGCTCTCAAATCCGCCCTATGGTAAGTCGTGGGCGAGCGAACAA
CGCCATATCAAAGATGGGAATGAGGTCATCGACAGTCGTTTCCGCATCAAGCTCAAAAACTACTGGGGCGTAGAGGAAGA
CGCCGATGCCATTCCACGCTCCAGTGATGGGCAGTTACTGTTTCTGATGGAAATGGTGAGCAAGATCAAACCGTTGGCAG
CTTCGCCGTCGGGCTCCCGGATTGCTTCGGTCCACAACGGCTCCAGCCTGTTTACGGGCGATGCCGGTGGGGGCGAAAGC
AACATTCGGCGGTATCTGATCGAAAACGATTTGCTCGACGCCATCATCCAGCTGCCCAACAACCTGTTCTACAATACAGG
TATCACCACCTATATCTGGGTATTGACGAACAGCAAACCCGCCAACCGACAGGGCAAGGTGCAACTCATTGACGCCGGAC
CGCTGTACCGCAAGCTGCGAAAGAACCTGGGGGCCAAGAACTGCGAACTAGCTCCCGAACACATCACCGAAATTGTCAAA
ACTTACCAGGATTTAGCTATAGTTGACCGTACCGGCGATGACGGTTTAGCCAGCAAGGTGTTTGACAACGCCGACTTTGG
GTATTATAAAGTGACCATCGAACGGCCCAAACGCCTGAAAGCACAGTTCAGCGCCGAACGTATTGCCGAACTTCGGTTCG
ATAATAAACTGCGCGAGCCGATGGTGTGGGCCTGGGAAACCTACGGCGAGCGGGTGTATACCGACCTGCCCGCCCTGGAA
AAAGACATCATCGACTGGTGCGAAAAACAGGAGCTGAATCTGGCCCGCAAGCAACAGGAAGCCCTGCTCAAGCCCGACAA
CTGGCTGAAGCAACAGGGCCTGATGAACACCGCTACCAAACTGATGAAGGCCATTGGTACGGACGAGTACAGCAATTTCA
ACATCTTTGCCCGCGAGGTAGAAATGGAGTTGAAAGCGCTGGGGCTGAAGCTATCGGCCTCGGAAAAGAAGCAGATCATG
GATGCCGTAAGCTGGTACGACGCCGAGGCCGAAAAGGTGATCAAAGGCACGACCAAACTGAAAGGCGAAAAGCTGACCGA
CCTGTTGGAGCACCTGAATTGCACCGAAGCCCAGCTACCTGACTTCGGTTATTTCGTTACCGGAACGCCGGACCGCGAAA
AGCCGGGTGAATACCTCGAATACGAAACCGAATCGGACCTGCGCGATACGGAGAATGTACCCCTTAAGGAAGACATCCAC
GACTATTTTCTGCGCGAAGTGAAGCCCCACGTTTCCGAAGCCTGGATTAACCTCGATGCTACTAAAATTGGTTACGAAAT
CAGCTTTAACAAGTACTTCTACCGCCATAAACCCCTGCGCGATATAGCGGCTGTCAGTGCCGATATCCTGCAACTGGAAG
ATGAAAGCGAAGGCCTGATTAAAGCCATTCTGGCGTGGAGTTGA

Protein sequence :
MNHQSHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDALLEPGKDEVMEEVRFQREEAGFTELDVNGLQAASG
YVFYNTSVWTLQKLHDTATNNQQLLEANFTDYLDGFSDNVKEIIRKFNLKSQVKHMANKDVLLDVLEKFTSPTINLTPFE
KLDPEGRKLPALSNLGMGYVFEELIRKFNEENNEEAGEHFTPREVIDLMTHVIFEPIKDRLPPVMTIYDPACGSGGMLTE
SQNFIKDEDGLIRAKGDVYLFGKEINDETYAICKSDMMIKGNDPENIKNGSTLSTDEFAGKQFDFMLSNPPYGKSWASEQ
RHIKDGNEVIDSRFRIKLKNYWGVEEDADAIPRSSDGQLLFLMEMVSKIKPLAASPSGSRIASVHNGSSLFTGDAGGGES
NIRRYLIENDLLDAIIQLPNNLFYNTGITTYIWVLTNSKPANRQGKVQLIDAGPLYRKLRKNLGAKNCELAPEHITEIVK
TYQDLAIVDRTGDDGLASKVFDNADFGYYKVTIERPKRLKAQFSAERIAELRFDNKLREPMVWAWETYGERVYTDLPALE
KDIIDWCEKQELNLARKQQEALLKPDNWLKQQGLMNTATKLMKAIGTDEYSNFNIFAREVEMELKALGLKLSASEKKQIM
DAVSWYDAEAEKVIKGTTKLKGEKLTDLLEHLNCTEAQLPDFGYFVTGTPDREKPGEYLEYETESDLRDTENVPLKEDIH
DYFLREVKPHVSEAWINLDATKIGYEISFNKYFYRHKPLRDIAAVSADILQLEDESEGLIKAILAWS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1769 NP_231404.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 68
VC0395_A1367 YP_001217310.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 68
VPI2_0017c ACA01834.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 68

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Slin_6258 YP_003391016.1 N-6 DNA methylase VFG1102 Protein 0.0 68