Gene Information

Name : Slin_5637 (Slin_5637)
Accession : YP_003390401.1
Strain : Spirosoma linguale DSM 74
Genome accession: NC_013730
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 6867060 - 6868199 bp
Length : 1140 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase

DNA sequence :
ATGAAATTCGGAACCAAAGCCATCCATGCCGGTATTGAGCCGGACCCCACAACGGGCGCGATTATGACGCCCATTTATCA
AACGTCGACCTACGTTCAGGAATCGCCGGGTAAGCACAAGGGATACGAATATGCCCGCACGCAGAACCCAACCCGGAATG
TTCTCCAGAATAACCTCGCTGCCCTTGAAAACGGGAAACATGGTATTTGCTACTCATCGGGCTTAGGCGCTACCGACGCC
ATCCTGAAGCTCTTCAAACCCGGCGACGAAATAATTGCCAGTAATGACCTTTATGGCGGCACATACCGCATCATGGTACG
CGTCTTTCAGGAATTCGGGCTGAAGTTCAATTTCGTGGATCTGTCGGATGCAACGAAGCTGGAAGCAGCTATCACACCCG
CCACAAAGATGGTCTGGATTGAAACACCAACCAACCCACTGCTTCGACTGGTAGACATCGCGGCTATAGCGGCTGTTACA
AAGCAGCACGGTATTCAATTGGTGGTCGATAACACCTTTGCCTCACCTTATCTGCAAAACCCGCTCGATTTAGGGGCCGA
TATTGTCATGCACTCGGTCACGAAATACCTCGGCGGGCACTCGGACACGGTCATGGGCGCTATCGTCCTGAACGACGACG
AAACGGCTCAGCGTTTAGCCTTTATTCAGAATGCCTGTGGTGCTGTTCCCGGTCCGCAAGATTGCTTTCTGGTGCTGCGC
GGCATCAAAACACTGCACGTTAGGATGCAGCGCCATTGCGAGAATGCACAGAAAGTCGCGGAATACTTACAGCAACACCC
AAAAGTGAGTCAAGTGCATTACCCCGGACTACCCTCACATATCGGCCATGAGCTGGCTAAGAAGCAAATGCGCGGCTTTG
GCGGTATGTTGTCATTTGAACTGAAAGGCGATTCGATGCCCGAAGCTGTCCGGGTAATGGAAAGCTTTGAGGTATTTTCG
TTAGGCGAATCGCTGGGGGGCGTCGAGTCGCTGTGTACGCACCCCGCCAGCATGACCCACGCCAGCATTCCGAAGGAAGA
ACGCATCAAAAACGGCCTCAAAGATACCCTCATCCGGCTCAGTGTCGGGATTGAGGATGTGGAGGATCTGATTCAGGATT
TGGAGCAGGCAATTGACTGA

Protein sequence :
MKFGTKAIHAGIEPDPTTGAIMTPIYQTSTYVQESPGKHKGYEYARTQNPTRNVLQNNLAALENGKHGICYSSGLGATDA
ILKLFKPGDEIIASNDLYGGTYRIMVRVFQEFGLKFNFVDLSDATKLEAAITPATKMVWIETPTNPLLRLVDIAAIAAVT
KQHGIQLVVDNTFASPYLQNPLDLGADIVMHSVTKYLGGHSDTVMGAIVLNDDETAQRLAFIQNACGAVPGPQDCFLVLR
GIKTLHVRMQRHCENAQKVAEYLQQHPKVSQVHYPGLPSHIGHELAKKQMRGFGGMLSFELKGDSMPEAVRVMESFEVFS
LGESLGGVESLCTHPASMTHASIPKEERIKNGLKDTLIRLSVGIEDVEDLIQDLEQAID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-91 52
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-92 52
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-66 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Slin_5637 YP_003390401.1 cystathionine gamma-lyase BAC0207 Protein 4e-80 45