Gene Information

Name : Slin_4077 (Slin_4077)
Accession : YP_003388863.1
Strain : Spirosoma linguale DSM 74
Genome accession: NC_013730
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 4905777 - 4907111 bp
Length : 1335 bp
Strand : -
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase; KEGG: sat:SYN_01113 UDP-N-acetyl-D-galactosamine 6- dehydrogenase

DNA sequence :
ATGTTTAAAATTAGGCTCAACGAATTTAACCACCAACAAGGCTTGCTAAACGACCTTCAACAGAAAGAAAAACAACTGGC
CGTTATCGGGTTGGGCTACGTGGGCCTACCGATAGCGCTGGCCTTTGCCCAACGGTTTCGGGTGGTGGGCTTCGATACCA
ACGCCGAACGGGTGGCTATGCTGCAACGGCACGAAGATCCATCGCGTCAGCTAAAGCCCGGCGATTTTACCGGGGCCGAT
ATCCGGTTTACCGCTAATCCCGATGACCTCCGAAACGCCCATTTTTTTGTTGTGGCGGTGCCTACACCGGTCGATGAGTA
CAAAGTCCCCGATCTGAAACCCCTGCAACGGGCGTCCGAAATCATTGGTCGTGTCCTGAAACCCGGCGACTACGTCGTCT
ATGAGTCTACCGTTTACCCCGGCTGTACCGAAGACGATTGCCTGCCGCTGCTGGAACAGTATTCCGGCCTGAAGCTGGGT
GATGACTTTAAGCTGGGCTACTCGCCGGAACGGATCAACCCCGGCGATAAGGTTCGAACGCTGACCGATATACTAAAAGT
AGTGTCGGGTAACGATGCCGAAGCAGTGCAGACAATTGCTGATGTATACGGCAGTATCATCCGGGCCGGTATATACGCTG
CGACCTCCATTAAGGTTGCCGAAGCAGCCAAGGTCATCGAAAATGTTCAGCGGGATCTCAACATATCGCTGATGAATGAA
TTGGCGGTCATTTTTGACAAAATGAGTATCGACACGCAGGAGGTACTGAAAGCTGCGTCGACGAAATGGAATTTTTTGCC
GTTTACGCCGGGGCTGGTCGGCGGGCATTGTATTGGCATTGACCCCTATTACCTTCTTTACAAATCGCGGCAGCTGGGTT
ATGAACCGCAGGTAATCAACTCGGGTCGGCGCGTCAACGACAGTATGCCCGCTTTTGTGGCCACCAAGCTGGTTCAGCTG
TTGCTCCAGCGCGAGAAGAATCCGGCGCAGACTAAAGTACTGGTCATGGGCCTCACATTCAAGGAAAACATTGCCGACAT
CCGCAACTCGAAAGTAGTCGACCTGGTGCGGGAGCTGATGAAATACGCCATCAACGTTCATATCGTTGATCCGTGCGCGT
CGCCGAACGAAGTAGCGCTCGACTACAAAATGACCCTGCTGGATGCACCGGTCGGCCGGTACGACGCCGTCATTGTTGCC
GTTGCCCACGACCAGTATCGCACACTGGATGTGGTCTATTTTAAGTCGCTGATGACGGAGCGGCCGATTTTACTGGATTT
GAAGGGATTGTATACCATAGGCCGGGAAGATGATCTAACCTACTGGCGATTATAA

Protein sequence :
MFKIRLNEFNHQQGLLNDLQQKEKQLAVIGLGYVGLPIALAFAQRFRVVGFDTNAERVAMLQRHEDPSRQLKPGDFTGAD
IRFTANPDDLRNAHFFVVAVPTPVDEYKVPDLKPLQRASEIIGRVLKPGDYVVYESTVYPGCTEDDCLPLLEQYSGLKLG
DDFKLGYSPERINPGDKVRTLTDILKVVSGNDAEAVQTIADVYGSIIRAGIYAATSIKVAEAAKVIENVQRDLNISLMNE
LAVIFDKMSIDTQEVLKAASTKWNFLPFTPGLVGGHCIGIDPYYLLYKSRQLGYEPQVINSGRRVNDSMPAFVATKLVQL
LLQREKNPAQTKVLVMGLTFKENIADIRNSKVVDLVRELMKYAINVHIVDPCASPNEVALDYKMTLLDAPVGRYDAVIVA
VAHDQYRTLDVVYFKSLMTERPILLDLKGLYTIGREDDLTYWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-101 50
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-100 50
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-100 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Slin_4077 YP_003388863.1 nucleotide sugar dehydrogenase VFG0431 Protein 4e-101 50