Gene Information

Name : Kfla_6807 (Kfla_6807)
Accession : YP_003384597.1
Strain : Kribbella flavida DSM 17836
Genome accession: NC_013729
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase (NAD(+))
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 7288414 - 7289937 bp
Length : 1524 bp
Strand : +
Note : PFAM: Aldehyde Dehydrogenase; KEGG: mxa:MXAN_5040 aldehyde dehydrogenase family protein

DNA sequence :
ATGACGATCTACGCCGCTCCCGGGCAAGCAGGCAGCCCGGCCGCCTTCAAGTCCCGCTACGACCACTTCATCGGTGGCGA
GTGGGTGCCGCCGGCCAAGGGCGGCTACTTCGAGAACCCGACGCCGGTCACCGGTGAGAACTTCACCGAGATCGCCCGCG
GCACCGCCGACGACGTCGAAGCCGCCCTGGACGCGGCGCACGGCGCGGCACCCGGCTGGGGCCGCACCTCGTCGTCGGAG
CGGGCCACCATCCTGAACCGGATCGCCGACCGGATCGAGGACAACCTCGAGCTGCTCGCGGTCGCCGAGACCTGGGACAA
CGGCAAGGCCGTGCGCGAGACGCTGGCCGCCGACATGCCGCTGGCGATCGACCACTTCCGGTACTTCGCCGGCGCGCTGC
GCGCCCAGGAGGGCTCGATCTCGCAGGTCGACGACGACACCGTGGCGTACCACTTCCACGAGCCGCTCGGCGTGGTCGCG
CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCGACCTGGAAGCTGGCCCCGGCGCTGGCGGCCGGCAACGCGGTGGT
GCTGAAGCCGGCCGAGCAGACCCCGGCCTCGATCCACGTGCTGATGGAGCTGATCGCCGACCTGCTGCCGCCGGGCGTGC
TGAACATCGTCAACGGCTTCGGCGTCGAGGCCGGCAAACCGCTTGCCTCCAGCAACAGAGTGGCGAAGGTCGCGTTCACC
GGTGAGACCACGACCGGCCGGCTGATCATGCAGTACGCGTCGGAGAACATCATCCCGGTCACCCTGGAGCTGGGCGGCAA
GAGCCCGAACATCTTCTTCGAAGACGTCGCGGCCAGCAAGGACGCCTTCTACGACAAGGCGCTCGAGGGCTTCACGATGT
TCGCGCTGAACCAGGGCGAGGTCTGCACCTGTCCGTCCCGGGCGCTGATCCAGGCCGGCATCTACGACTCGTTCCTGGCC
GACGCGAAGGCGCGCACCGAGGCGGTCAAGCAGGGCAACCCGCTGGACACCGACACGATGATGGGCGCGCAGGCCAGCAA
CGACCAGTACGAGAAGATCCTGTCCTACATCGACATCGGCAAGGCCGAGGGCGCCAAGGTGATCACCGGCGGCGAGAAGG
CCGACCTGGGCGGTGAGCTGAGCGGCGGCTACTACATCCAGCCGACGATCTTCGAGGGCGAGAACAAGATGCGGATCTTC
CAGGAGGAGATCTTCGGGCCGGTGGTCTCGGTGACCCGGTTCGACGACTACGCCGACGCGCTGAAGATCGCCAACGACAC
CCTGTACGGTCTCGGCGCCGGGGTCTGGTCGCGGGACATCAACACGGCGTACCGGGCGGGCCGGGAGATCCAGGCCGGCC
GGGTCTGGACGAACTGCTACCACGCCTATCCCGCGCACGCGGCGTTCGGCGGCTACAAGAACTCGGGCATCGGCCGGGAG
AACCACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTGGTCAGCTACTCGCCCGACAAGCTCGGCTTCTT
CTAG

Protein sequence :
MTIYAAPGQAGSPAAFKSRYDHFIGGEWVPPAKGGYFENPTPVTGENFTEIARGTADDVEAALDAAHGAAPGWGRTSSSE
RATILNRIADRIEDNLELLAVAETWDNGKAVRETLAADMPLAIDHFRYFAGALRAQEGSISQVDDDTVAYHFHEPLGVVA
QIIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPASIHVLMELIADLLPPGVLNIVNGFGVEAGKPLASSNRVAKVAFT
GETTTGRLIMQYASENIIPVTLELGGKSPNIFFEDVAASKDAFYDKALEGFTMFALNQGEVCTCPSRALIQAGIYDSFLA
DAKARTEAVKQGNPLDTDTMMGAQASNDQYEKILSYIDIGKAEGAKVITGGEKADLGGELSGGYYIQPTIFEGENKMRIF
QEEIFGPVVSVTRFDDYADALKIANDTLYGLGAGVWSRDINTAYRAGREIQAGRVWTNCYHAYPAHAAFGGYKNSGIGRE
NHKMMLDHYQQTKNLLVSYSPDKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-148 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-156 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-156 61
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-156 61
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-156 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kfla_6807 YP_003384597.1 aldehyde dehydrogenase (NAD(+)) VFG0082 Protein 8e-149 62