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Name : Kfla_5968 (Kfla_5968) Accession : YP_003383770.1 Strain : Kribbella flavida DSM 17836 Genome accession: NC_013729 Putative virulence/resistance : Resistance Product : dihydrofolate reductase Function : - COG functional category : H : Coenzyme transport and metabolism COG ID : COG0262 EC number : 1.5.1.3 Position : 6409643 - 6410104 bp Length : 462 bp Strand : + Note : PFAM: dihydrofolate reductase region; KEGG: mno:Mnod_0700 dihydrofolate reductase region DNA sequence : ATGAGCGTCGTACTGATCGCGGCGGTCGGTCGCAACGGCGTGATCGGCCGGGACAACGAGCTGCCCTGGCGCATCCGCGA GGACCTCCAGCACTTCAAGGCCCTCACCCTGGGCCACACCCTGGTGATGGGCCGCAAGACCTACGACTCGATCGGCCGCC CGCTGCCCGGACGCCGGACGGTCGTGGTCACCCGGCAGCCGGACTGGTCCGCGCCCGGCGTCGAGGTCGCGCACAGCCTG GCCGCCGCGCTCGAGCTTGCCGACGGCAAGGACGTCTACGTGGCCGGCGGCGGCGAGATCTACCGTCAGGCGCTGCCGTC CGCCGACCGGCTGGAGCTGACCGAGGTCGACCAGTCCCCCGCGGGCGACGTCACCTTCCCCGCCGTCGACCGCTCCGCCT GGACCGAGACCGCCCGCGAACCGCACGACGGCTTCGCCTTCGTCACCTACGTCCGGTCCTGA Protein sequence : MSVVLIAAVGRNGVIGRDNELPWRIREDLQHFKALTLGHTLVMGRKTYDSIGRPLPGRRTVVVTRQPDWSAPGVEVAHSL AAALELADGKDVYVAGGGEIYRQALPSADRLELTEVDQSPAGDVTFPAVDRSAWTETAREPHDGFAFVTYVRS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| dfrA1 | ADZ05803.1 | trimethoprim-insensitive dihydrofolate reductase | Not tested | AbaR3 | Protein | 1e-19 | 44 |
| unnamed | AEL12695.1 | DfrA5 | Not tested | AbaR21 | Protein | 1e-19 | 44 |
| dfrA5 | AFG30110.1 | dihydrofolate reductase | Not tested | PAGI-2 | Protein | 4e-18 | 43 |
| dfrA5 | AET25387.1 | dihydrofolate reductase | Not tested | PAGI-2(C) | Protein | 4e-18 | 43 |
| folA-2 | YP_189146.1 | dihydrofolate reductase | Not tested | ¥ÕSP¥â | Protein | 2e-22 | 42 |
| dfrA12 | ACF06156.1 | dihydrofolate reductase | Not tested | Tn5036-like | Protein | 3e-25 | 41 |
