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Name : Kfla_3620 (Kfla_3620) Accession : YP_003381476.1 Strain : Kribbella flavida DSM 17836 Genome accession: NC_013729 Putative virulence/resistance : Resistance Product : D-alanine/D-alanine ligase Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1181 EC number : 6.3.2.4 Position : 3893318 - 3894346 bp Length : 1029 bp Strand : + Note : KEGG: cvi:CV_2472 D-alanyl-alanine synthetase A; TIGRFAM: D-alanine/D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP- grasp; protein of unknown function DUF201 DNA sequence : ATGAAGATCGGAATTCTGTTCGGGGGCGTCTCCGAGGAACACCCCATCTCGCTCAAGTCCGCGCGCGAGGTCGCCCGCAG CCTCGACCCCGAAAGGTACGAGCCGTACTACGTCGGGATCACCCGAGGCGGCGCCTGGATGCTCTGCGACGGCCCGGACG ACGACTGGGAGAACGGCACGGGCCGCCCCGCCGTACTGTCACCGGACCGCACCGTGCACGGACTGCTCGTGCTGGAGCAG GGCCGGTACGAGACGATCAGGCTCGACGTGGTGCTGCCCGTTCTGCACGGCAGGCTCGGCGAGGACGGTGCGATCCAGGG CCTGCTGGAGCTCTCCGGTATCCCCTACGTCGGCTGCGACATCCCGAGTTCCGCGCTGTGCATGGACAAGTCCCTGGCTT ACGTCGTCGCCCGGAGCGCGGGAATCGCCACGCCGAACTTCTGGACCGTCGCGGCCAAGGAACTCCCCGACGCCGACCTG ACCTATCCGGTTTTCGTGAAGCCGGCCCGGTCAGGGTCGTCGTTCGGCGTCAGCAAGGTGACCCAGGCGGACGACCTGCC GAGTGCTGTCGAAGTGGCGAGCCAGTACGACTCGAAGGTCCTGATCGAGCAAGCTGTCGTGGGCCGCGAGATCGGCTGTG CGGTCCTGGGCAACGGTGGTGACCTGGTCGTCGGCGAGGTGGACCACATCGCGCTGTCGCACGGCTTCTTCCGGATTCAT CAGGAGAGTGAGCCCGAGAGCGGTTCCGACAACTCGACGGCCATCGTTCCCGCCGACATCCCGGCCGCGTCGCGCACGCT TGTTCGGGACACCGCCAAGGCCGTGTACCGGGCGCTCGGGTGCGGCGGCCTGGCGCGCGTCGACCTGTTCCTCACCGAGG ACGGCGCGGTCGTGCTCAACGAGGTGAACACCTTGCCGGGGCTGACGTCGTACAGCCGCTACCCGAGAATGATGGCCGCC GCAGGACTGTCGATGGGCGAAGTGATCGACCGCGTCGTCTCGCTGGCACTGACGGGCAACAAGCGATGA Protein sequence : MKIGILFGGVSEEHPISLKSAREVARSLDPERYEPYYVGITRGGAWMLCDGPDDDWENGTGRPAVLSPDRTVHGLLVLEQ GRYETIRLDVVLPVLHGRLGEDGAIQGLLELSGIPYVGCDIPSSALCMDKSLAYVVARSAGIATPNFWTVAAKELPDADL TYPVFVKPARSGSSFGVSKVTQADDLPSAVEVASQYDSKVLIEQAVVGREIGCAVLGNGGDLVVGEVDHIALSHGFFRIH QESEPESGSDNSTAIVPADIPAASRTLVRDTAKAVYRALGCGGLARVDLFLTEDGAVVLNEVNTLPGLTSYSRYPRMMAA AGLSMGEVIDRVVSLALTGNKR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vanB | YP_008394259.1 | Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase | Not tested | Not named | Protein | 1e-108 | 63 |
| vanB | NP_815951.1 | D-alanine--D-lactate ligase | Not tested | Not named | Protein | 1e-107 | 63 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Kfla_3620 | YP_003381476.1 | D-alanine/D-alanine ligase | AY145441.gene.p01 | Protein | 1e-108 | 63 |
| Kfla_3620 | YP_003381476.1 | D-alanine/D-alanine ligase | NC_005054.2598280.p0 | Protein | 2e-107 | 63 |
| Kfla_3620 | YP_003381476.1 | D-alanine/D-alanine ligase | AF310956.2.orf5.gene | Protein | 2e-108 | 63 |
| Kfla_3620 | YP_003381476.1 | D-alanine/D-alanine ligase | NC_014475.1.orf3.gen | Protein | 2e-107 | 63 |
| Kfla_3620 | YP_003381476.1 | D-alanine/D-alanine ligase | U35369.1.gene6.p01 | Protein | 6e-108 | 63 |
| Kfla_3620 | YP_003381476.1 | D-alanine/D-alanine ligase | AE016830.1.gene2250. | Protein | 6e-108 | 63 |
| Kfla_3620 | YP_003381476.1 | D-alanine/D-alanine ligase | U00456.gene.p01 | Protein | 6e-108 | 63 |
| Kfla_3620 | YP_003381476.1 | D-alanine/D-alanine ligase | AF277571.gene.p01 | Protein | 3e-111 | 62 |
| Kfla_3620 | YP_003381476.1 | D-alanine/D-alanine ligase | AY489045.gene.p01 | Protein | 3e-107 | 61 |
| Kfla_3620 | YP_003381476.1 | D-alanine/D-alanine ligase | AF130997.1.orf4.gene | Protein | 4e-108 | 59 |
| Kfla_3620 | YP_003381476.1 | D-alanine/D-alanine ligase | AF162694.gene.p01 | Protein | 2e-53 | 41 |
