Gene Information

Name : Kfla_3077 (Kfla_3077)
Accession : YP_003380940.1
Strain : Kribbella flavida DSM 17836
Genome accession: NC_013729
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3281314 - 3282756 bp
Length : 1443 bp
Strand : +
Note : KEGG: mxa:MXAN_6299 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence :
GTGCGTCGCGCAAAGATCGTTTGTACGCTCGGCCCGGCTACGGCCGCCCCCGAGCGCATCCTGGAACTCGTCCAAGCAGG
TATGGACGTCGCTCGGCTGAATCTCAGCCACGGCGCCCACGCCGAGCATGAGCGCATCTACCAGCGAATCCGGACCGCAG
CGGCCGAGACCGGCAAGAACGTCGGGATCCTGGTCGACCTGCAAGGCCCGAAGATCCGGCTGGCGGAGTTCGCCGAAGGC
AAGGTCACGCTGACCTACGGCGAGCGCTTCACCATCACCACCCGGGAGGTGCCCGGTGACGTGACCGTCTGCGGTACGAC
GTACGACGGGCTGCCCGGCGACGTCAGACCCGGTGATCCGCTGCTCATCGACGACGGCCGCATCGCGCTGGTCGCCGAGG
AGGTGACCGAGACCGACGTGATCTGCCGGGTCACCGTCGGTGGGCCGGTGTCGAACAACAAGGGCATCAACCTGCCCGGT
GCCACGGTGAGCGTGCCGGCGATGTCGGAGAAGGACGTGGAGGACCTGCGCTGGGCCCTGCACCTGCCGGCCGACATGAT
CGCGATGTCGTTCGTCCAGCGGGCCTCCGACATCCAGATCGTGCACAAGATCATGGATGAGGAGGGTCACCGGGTCCCGG
TGGTCGCCAAGATCGAGAAGCCGCAGGCGGTCGCGAACCTGGACGAGATCATCGAGGCCTTCGACGGCTTCATGGTCGCC
CGCGGCGACCTCGGCGTGGAGCTCCCGCTGGAGGAGGTCCCGCTGGTCCAGAAGCTGATCATCGACCAGGCCCGGCTGAA
CGCGAAGCCGGTGATCGTCGCCACCCAGATGCTGGAGTCGATGATCTCCGCGCCGCGGCCGACCCGCGCCGAGGCCTCCG
ACGTCGCCAACGCGGTGCTCGACGGCGCCGACGCGGTGATGCTGTCCGGAGAGACCAGCGTCGGCCGGTTCCCGATCGAG
ACCGTCAAGACGATGGCCCGGATCGTGGAGTCGACCGAGGAGCACGGCCTCAGCCGGGTCAAGGAGATCGACTGGGAGCC
GCGCACCAAGGCCGGCGTCATCGCCCGCGCCGCGGCCGACGTCGCCGAGCGGATGGAGGCGAAGTACCTGGTCGCCTTCA
CCCAGTCCGGCGACACCGCGCTCCGGCTGGCCCGCTACCGCACCGAGATCCCGGTGCTCGCGTTCACCCCGGTCCCGTCG
GTGAGCGCCTGGCTGAGCGTCGTGTGGGGTATCGAGACGCACATCGTCCCCACCGTCGACCACACCGACGACATGGTCCG
CCAGGTCGACCAGCGCCTGCTCGAGCTCGGCAAGCTCCAGAAGGGCGACCTGGTCGTCATCGTCGCCGGCAGCCCACCCA
GCATCCCCGGCTCCACCAACGCCCTCCGCGTCCACCGCATGGGCGACGCCATCGCCGGCATCGCCCCGGCGTACCGGCAG
TAG

Protein sequence :
MRRAKIVCTLGPATAAPERILELVQAGMDVARLNLSHGAHAEHERIYQRIRTAAAETGKNVGILVDLQGPKIRLAEFAEG
KVTLTYGERFTITTREVPGDVTVCGTTYDGLPGDVRPGDPLLIDDGRIALVAEEVTETDVICRVTVGGPVSNNKGINLPG
ATVSVPAMSEKDVEDLRWALHLPADMIAMSFVQRASDIQIVHKIMDEEGHRVPVVAKIEKPQAVANLDEIIEAFDGFMVA
RGDLGVELPLEEVPLVQKLIIDQARLNAKPVIVATQMLESMISAPRPTRAEASDVANAVLDGADAVMLSGETSVGRFPIE
TVKTMARIVESTEEHGLSRVKEIDWEPRTKAGVIARAAADVAERMEAKYLVAFTQSGDTALRLARYRTEIPVLAFTPVPS
VSAWLSVVWGIETHIVPTVDHTDDMVRQVDQRLLELGKLQKGDLVVIVAGSPPSIPGSTNALRVHRMGDAIAGIAPAYRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-72 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-72 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-72 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-72 41
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 2e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kfla_3077 YP_003380940.1 pyruvate kinase VFG0479 Protein 1e-72 41