Gene Information

Name : Kfla_1249 (Kfla_1249)
Accession : YP_003379151.1
Strain : Kribbella flavida DSM 17836
Genome accession: NC_013729
Putative virulence/resistance : Resistance
Product : MerR family transcriptional regulator
Function : -
COG functional category : K : Transcription
COG ID : COG0789
EC number : -
Position : 1309239 - 1309670 bp
Length : 432 bp
Strand : +
Note : PFAM: Transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR; KEGG: pap:PSPA7_0115 Hg(II)-responsive transcriptional regulator

DNA sequence :
ATGAGTGACACGTTGCGCCCCGGACAGGTCGCCGCGGCGGCCGGCGTCAACCTGCAGACCCTCCGGTACTACGAACGCCG
CGGCCTGCTCGACCCGCCCGACCGCAGCCTCGGCGGCCACCGGCAGTACTCCGGCGAGGCGGTCACCACCCTCCGCGTGA
TCAAGGCCGCGCAACGCCTCGGCTTCACGCTGACCGAGATCGCCGACCTGCTCGAGACCGCCCGCCACCGCCACGGCCCC
GGCGAGGCAGCAGGCCTGCAGGTCCGGGCCCGCGAGAAACTGGCCGACGTGGAGACCAAGATCGCCGACCTCACGGTCAT
CGCCGACACCCTGCGGGCGGCGCTGTCCGCCGGCTGCGACGACCTGACCACCTGCGCCGGTACGCCGGACTGCCCGATCC
CGTTCACCGACCTGGCCCGGCGTACGCCGTGA

Protein sequence :
MSDTLRPGQVAAAAGVNLQTLRYYERRGLLDPPDRSLGGHRQYSGEAVTTLRVIKAAQRLGFTLTEIADLLETARHRHGP
GEAAGLQVRAREKLADVETKIADLTVIADTLRAALSAGCDDLTTCAGTPDCPIPFTDLARRTP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merR CAJ77064.1 Mercury resistance operon regulatory protein Not tested AbaR1 Protein 8e-18 43
merR ACN81009.1 MerR activator/repressor of mer operon Not tested AbaR5 Protein 1e-17 43
unnamed ABR13397.1 mercuric resistance operon regulatory protein Not tested PAGI-5 Protein 1e-17 42
merR AGK07025.1 MerR Not tested SGI1 Protein 2e-16 41
merR AGK07083.1 MerR Not tested SGI1 Protein 2e-16 41
merR ACK44535.1 MerR Not tested SGI1 Protein 8e-17 41
merR AET25401.1 MerR Not tested PAGI-2(C) Protein 8e-17 41
merR AFG30124.1 MerR Not tested PAGI-2 Protein 8e-17 41
merR YP_006098391.1 mercuric resistance operon transcriptional regulator Not tested Tn2411 Protein 1e-16 41
EXB37 ABD94723.1 putative regulator of mercury resistance conferring proteins Not tested ExoU island B Protein 7e-19 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kfla_1249 YP_003379151.1 MerR family transcriptional regulator BAC0684 Protein 8e-18 42
Kfla_1249 YP_003379151.1 MerR family transcriptional regulator BAC0232 Protein 4e-17 42
Kfla_1249 YP_003379151.1 MerR family transcriptional regulator BAC0686 Protein 2e-17 42
Kfla_1249 YP_003379151.1 MerR family transcriptional regulator BAC0688 Protein 6e-18 42
Kfla_1249 YP_003379151.1 MerR family transcriptional regulator BAC0687 Protein 4e-17 42
Kfla_1249 YP_003379151.1 MerR family transcriptional regulator BAC0689 Protein 2e-17 42
Kfla_1249 YP_003379151.1 MerR family transcriptional regulator BAC0683 Protein 3e-17 41