Gene Information

Name : leuS (HMPREF0424_0944)
Accession : YP_003374157.1
Strain : Gardnerella vaginalis 409-05
Genome accession: NC_013721
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1084873 - 1087857 bp
Length : 2985 bp
Strand : -
Note : identified by match to protein family HMM PF08264; match to protein family HMM PF09334; match to protein family HMM TIGR00396

DNA sequence :
ATGAACGACAACGATCAACAGTATGCAACAGCTGACAACAAAGCTACTATTGCTGAGCCAGCTTTTCGTTACAACGCGCA
GCTCGCACAAGATATTGAGCAGCGCTGGCAAAAAACCTGGGATGAACAAGGTACGTTCTGGGCTGCTAATGTTAAAGGCG
ATTTGAAGGATGGTGAAGGCAAGCTTGCTGACGGTCGTCCTTCTTTCTTTGCAATGGACATGTTCCCGTATCCTTCCGGC
AAAGGCTTACACGTTGGACATCCTCTTGGATATTTGGCAACGGATGTTGTAAGCCGCTACCATCGCATGAAGGGTGAGAA
TGTTCTTCATGCAATGGGTTACGACGCTTTTGGTTTGCCGGCGGAACAGTACGCTGTTCAAACTGGTCAGCATCCGCGCA
TCACCACTGAGGCAAATATTGCTAATATGCGCAGGCAGTTGCATCGTATGGGCTTGAGTTTTGACGATCGTAGGTCTTTT
GCAACGATTGACACAAATTATGTGCGTTGGACGCAATGGATTTTCTCGAAGCTTTATGACGCTTGGTATGACACTGATTT
TGTGCGCAAAGACGGCGGAAAGGGTTCTGCTCGTCCGATTGCTGAACTCGTTGATGAGTTTAAGAGCGGCAAGCGCGAAA
TTCCTGGTTTTGCAGGCAAAAAGTGGGAAGAGCTTAATAAAGTAGAGCAAGCGGATGTATTAAACAATTTCCGCATTGCT
TATATTTCTAAATCTCCTGTAAATTGGTGCCCAGGCTTGGGAACTGTGCTTGCAAACGAGGAAGTTACTGCAGAAGGTAA
GTCTGAACGCGGAAACTTCCCAGTATTCCAGCGCAACCTTCGCCAGTGGTCCATGCGAATTACCGCTTATGGACACCGCT
TGGTGGAAGATTTGAACACTATTGATTGGTCAGAAAAAGTTAAGCTTATGCAGCGAAACTGGATCGGCGAATCTCACGGT
GCATCTGTGCACTTTGAAGTGCCATGTGCGGACGGCGAAACGCGCGATTTGGAAGTGTACACTACTCGTCCAGACACGCT
TTTTGGTACAACGTTTGCGGTTGTTTCCGTAGATCACCCAATTCTTGAGCATGTTCCAGAAGCTTGGGGTGCGGACGTTC
CAGAAAGCTGGAAGGGCGGTTACGCAAGTCTTAAAGAAGGCTTGGCAGAGTATCAAGCTCAAGCTCGCGCGAAGACTGCT
AAAGATCGCACGGAAGATGCAGGAGCAAAAACCGGCTTGTTTACTGGTCTTTACGCAATTAATCCTGTAAATGGAGCAAA
ACTTCCGCTGTTTGCTGCTGACTACGTGCTTATGGGTTACGGTACAGGCGCAATTATGGCGGTTCCTGGCGGCGACCAGC
GCGATTATGATTTCGCAAAAGCATTCGGTTTGCCAGTAATTTACACTGTTGAGCCTTTGCCTGATTCCGAAGAAAAGTTG
GCAGATTACGAAGGTAAAGCTCCGTTTGTTTCTCACGACGGAATTGTTATTAATTCAGCAGTAGAACATACGCACAAGCT
TGGTGACGCTTTGTCTATTAACGGTTTGCGCGTAGACGAAGCTATTAAAAAGGTGACTACTTGGCTTGAAGCTGCAGGCG
TAGGAAAAGGTAGGGTTTCTTACCGACTTCGCGACTGGCTGTTCTCTCGCCAGCGCTACTGGGGTGAGCCATTCCCAATC
GTTTATGACGAAGATGGTGTTGCTCACTTAGTGCCAGATAGCGAGCTTCCAATTGCATTGCCGGACGTTCCTGACTATCA
GCCAAAAACTTACGCTCCAGACGATGCAAATTCGGAGCCTGAAGCACCTTTGAGCCGAAACGAAGATTGGGTAAAAGTTC
AGCTCGACCTTGGCGATGGCGTAAAAACCTACTATCGTGACACCAACACTATGCCGAACTGGGCTGGTTCTTGCTGGTAT
TACATGCGCTACTTGGATCCAAACGATGCTGAGCATATGGTTGACAGCGATGAATACGACTACTGGATGGGCACAAACCG
TCCAGGAAAAGAGCACGTATCTGGAGGCGTTGACCTTTACGTTGGTGGTGTAGAGCATGCAGTTTTGCACTTGCTTTACT
CGCGCTTCTGGCATAAGGCGCTTTACGACTTGGGTTACGTGGATTCTGCTGAACCATTCCACCGCTTGTTTAACCAGGGT
ATGATTCAAGCTTACGCTTACACGGATGAGCGCGGACAGTACGTTCCTGCTGACGAGGTTGAAGAAGGTGCTTCAAACAG
CGCTGGTGAGCCAACCTTTACATGGCATGGCGAGAGCGTGAACCGCGAGTTCGGCAAAATGGGCAAGAGCTTAAAGAATA
TTGTGACTCCAGATTACATGTACGAAAACTACGGTGCAGATACGTTCCGCTTGTACGAAATGAGCATGGGTCCGCTTTCT
GAGTCTCGTCCATGGAACACGCGTAACGTTGTTGGTGGCATGCGATTCTTGCAGCGCTTGTGGCGTAACGTTGTGAACGA
AGAAACCGGAGCTTGCGTGGTAACTGACGACGCTTTGGATGAGAAGACGTTGAAGATTCTTAACAACACAATTGCAGAAG
TGACTGTGGAAATGGAAGCAATGCGTCCAAATACTGCAATTGCTAAGCTGATTGTGCTTAACAACCACTTGACTTCGCTT
CCTCACGTGCCGCGAGCAGCTGTCGAGCCGCTGGTTCTTATGCTGGCTCCAATCGCGCCGCATATTTGCGAAGAAATGTG
GAGCAAGCTTGGACACGCAAAGTCGATTGCTCACGCAGATTGGCCTGTTGCGGATTCTCGCTACGTTGGTGAGGATACTG
TTACTGCCGTTGTGCAAATAAAGGGCAAGGTTCGAGCAAAGCTTGAAGTTGATCCAAATATTGACGCTTCTGAACTTGAA
AAGCTTGCGCTAGAAGCTGTAGCTGATCGCTTGGGCGGTAAGGCTCCGCGCAAGGTGATTGTGAAGGCTCCGAAGATTGT
GTCTATTGTGCCGGACGAAAGCTGA

Protein sequence :
MNDNDQQYATADNKATIAEPAFRYNAQLAQDIEQRWQKTWDEQGTFWAANVKGDLKDGEGKLADGRPSFFAMDMFPYPSG
KGLHVGHPLGYLATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEANIANMRRQLHRMGLSFDDRRSF
ATIDTNYVRWTQWIFSKLYDAWYDTDFVRKDGGKGSARPIAELVDEFKSGKREIPGFAGKKWEELNKVEQADVLNNFRIA
YISKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRNLRQWSMRITAYGHRLVEDLNTIDWSEKVKLMQRNWIGESHG
ASVHFEVPCADGETRDLEVYTTRPDTLFGTTFAVVSVDHPILEHVPEAWGADVPESWKGGYASLKEGLAEYQAQARAKTA
KDRTEDAGAKTGLFTGLYAINPVNGAKLPLFAADYVLMGYGTGAIMAVPGGDQRDYDFAKAFGLPVIYTVEPLPDSEEKL
ADYEGKAPFVSHDGIVINSAVEHTHKLGDALSINGLRVDEAIKKVTTWLEAAGVGKGRVSYRLRDWLFSRQRYWGEPFPI
VYDEDGVAHLVPDSELPIALPDVPDYQPKTYAPDDANSEPEAPLSRNEDWVKVQLDLGDGVKTYYRDTNTMPNWAGSCWY
YMRYLDPNDAEHMVDSDEYDYWMGTNRPGKEHVSGGVDLYVGGVEHAVLHLLYSRFWHKALYDLGYVDSAEPFHRLFNQG
MIQAYAYTDERGQYVPADEVEEGASNSAGEPTFTWHGESVNREFGKMGKSLKNIVTPDYMYENYGADTFRLYEMSMGPLS
ESRPWNTRNVVGGMRFLQRLWRNVVNEETGACVVTDDALDEKTLKILNNTIAEVTVEMEAMRPNTAIAKLIVLNNHLTSL
PHVPRAAVEPLVLMLAPIAPHICEEMWSKLGHAKSIAHADWPVADSRYVGEDTVTAVVQIKGKVRAKLEVDPNIDASELE
KLALEAVADRLGGKAPRKVIVKAPKIVSIVPDES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 6e-137 45