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Name : clpB (HMPREF0424_0092) Accession : YP_003373359.1 Strain : Gardnerella vaginalis 409-05 Genome accession: NC_013721 Putative virulence/resistance : Virulence Product : ATP-dependent chaperone protein ClpB Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 109250 - 111844 bp Length : 2595 bp Strand : + Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346 DNA sequence : ATGGAACAAAAGTTTACAACCTTAGCGCAAGACGCATTAAGTGATGCTGTGCAAAGTGCAGCGGCTGCTGGCAATGCGCA AGTAGATACGTTACATTTGGCAGATGCTTTACTTCGTCAAGAGCAGGGCGTCGTTCGCGCGCTTATTGCGCAAACGGGGG CAGATGCGCAACAAATCGGTGCTGAAATTCGCAACGCATTAGTGGCATTGCCTTCATCTACTGGCTCAACTACAACTAAG CCAGATGCAAGTCGTCAGCTTTTGGCTGCGCTAAGCCAGGCAGAAAAAGAGATGCACGCAATGGGAGACGAATACGTTTC TACGGAGCACATGCTTATTGGCATAGTTGCAAGCGCGCCGAATGCTGTTGCGGATATTTTCAAAAAGCACAACGTTTCCG CAGACGCGTTGCGAAAAGCTGTGCCAACTGTACGCGGTGGCGCAAAAGTGACAAGTCCGGATGCTGAAGGTAACTACAAA GCGCTTGAAAAGTATTCTGTTGATATGACTGCGCGCGCTCGTGAGGGAAAGCTTGATCCAGTAATTGGACGCGATCAGGA GATTCGCCGCGTGATTCAGATTCTTTCTCGCCGCACGAAGAATAATCCTGTGCTAATTGGCGAGCCGGGCGTTGGTAAAA CGGCAGTTGTAGAAGGATTGGCTCAGCGAATTGTGGCAGGGGATGTGCCTACGACTTTGCAAAACAAGCGTCTTATCAGT CTTGACTTGGCTTCGATGGTTGCAGGTTCGAAGTATCGCGGCGAGTTTGAGGAACGCTTAAAGGCAGTGTTGAAGGAAAT TCAACAATCAGACGGTCAAATTATTACGTTTATTGACGAAATTCACACTGTTGTTGGCGCGGGATCTGCAGAAGGTTCAA TGGATGCTGGCAATATGCTTAAGCCAATGCTTGCGCGCGGTGAGCTGCGCTTGGTTGGCGCGACTACGCTTAACGAGTAT CGTGAGCATATTGAAAAGGATTCTGCGCTTGAACGCAGATTCCAGCAAGTGTTTGTTGGCGAGCCATCTGTTGAAGATAC GGTGACGATTTTGCGTGGACTTAAGCAACGTTACGAAGCGCACCACAAGGTGACGATTAGTGACGATGCAATCGTAGCTG CAGCAACGCTTTCAAACCGCTATATTACCGGTCGTCAGCTTCCAGATAAGGCGATTGATTTGGTGGATGAAGCGGCAGCT CACTTGCGTATGGAGCTTGATTCTCAGCCAGAAGAAATCGATGAATTGCAGCGCAAAGTTACGCGTCTTGAAATGGAGGA AATGCAATTAAAGAAAGCGGAAGATGCTGCTGCGCGCGAACGCTTAGAAAAGTTGCAGGAAGAATTGGCAAACTCGCGCG AAAAGCTTGCTGGATTGAAAGCGCGTTGGGATGCGGAAAAAGCTGGCCATAACAAGGTTGGTGATTTGCGAGCGCAACTT GACGCTAAGCGCGTAGAAGCCGACAAATTCACACGTGAAGGCAACTTGGAACAAGCAAGCCGTATTTTGTATGGCGAAAT TCCAAGCATTCAAAAAGCTTTGGAAGAAGCGGAATCACAGGCTGCTAACGCTAAGAGTGAAGCGAAAGAGCCAATGGTTC CGGATCAGGTTGATGCTGATTCTATTGCAGGAGTCGTTAGCGAATGGACGGGCATTCCTGTTGGTCGCTTGATGCAAGGC GAAAATGAGAAGCTGCTCAACATGGAAAAGGAGCTTTCTAAGCGTGTGGTTGGTCAAAGTGAAGCAATTCAGGCTATAGC GGATGCTGTGCGCAGAAGCCGCGCTGGAATTGCAGACCCTAATCGCCCAACTGGTTCCTTCTTGTTCTTGGGTCCTACTG GCGTTGGTAAGACGGAGCTTGCAAAGGCTCTTGCTGACTTTTTGTTTGACGACGAGCGCGCAATGGTTCGCATTGATATG AGCGAGTACATGGAAAAGGCTTCCGTATCGCGGCTTATCGGTGCTGCTCCTGGTTACATTGGCTACGAGGAAGGCGGCCA GCTTACTGAAGCTGTGCGTAGACGTCCGTATTCTGTAGTGCTTTTTGACGAAGTCGAGAAGGCACATCCAGAAGTATTCG ACGTTTTGTTGCAGGTTTTGGACGATGGTCGTTTGACTGACGGACAAGGTAGAACGGTTGATTTTACGAATACGATTTTG ATTATGACATCAAACTTGGGTTCGCAATTCCTTGTACAAGAAGGCTTGGACGATGCTGCTAAACGCAAGGCTGTTATGAA CGCTGTTCACGCTGAGTTTAAGCCAGAGTTCATTAACCGTTTGGATGAGCTTGTTATGTTCCATCCGTTGAGCCGCGAAG AGCTTGGTGGAATTGTGGATATTCAAGTTCGTCAAGTGGCTGCACGCTTGAGCGACCGCCGTATTAGCTTGGATGTGAGT GATTCTGCTCGCGCTTGGCTTGCGGAGCATGGCTATGATCCAGTTTATGGTGCTCGTCCGTTGCGTAGATTGGTTCAAAC GGAAATTGGCGATCAACTTGCGCGATTGTTGCTTTCTGGAAAGGTGCATGATGGTGCACGCGTAGTTGCGGATTGTGAGA ATACTAGCGACCATGTGACCCTAAAGATTGCGTAG Protein sequence : MEQKFTTLAQDALSDAVQSAAAAGNAQVDTLHLADALLRQEQGVVRALIAQTGADAQQIGAEIRNALVALPSSTGSTTTK PDASRQLLAALSQAEKEMHAMGDEYVSTEHMLIGIVASAPNAVADIFKKHNVSADALRKAVPTVRGGAKVTSPDAEGNYK ALEKYSVDMTARAREGKLDPVIGRDQEIRRVIQILSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVAGDVPTTLQNKRLIS LDLASMVAGSKYRGEFEERLKAVLKEIQQSDGQIITFIDEIHTVVGAGSAEGSMDAGNMLKPMLARGELRLVGATTLNEY REHIEKDSALERRFQQVFVGEPSVEDTVTILRGLKQRYEAHHKVTISDDAIVAAATLSNRYITGRQLPDKAIDLVDEAAA HLRMELDSQPEEIDELQRKVTRLEMEEMQLKKAEDAAARERLEKLQEELANSREKLAGLKARWDAEKAGHNKVGDLRAQL DAKRVEADKFTREGNLEQASRILYGEIPSIQKALEEAESQAANAKSEAKEPMVPDQVDADSIAGVVSEWTGIPVGRLMQG ENEKLLNMEKELSKRVVGQSEAIQAIADAVRRSRAGIADPNRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMVRIDM SEYMEKASVSRLIGAAPGYIGYEEGGQLTEAVRRRPYSVVLFDEVEKAHPEVFDVLLQVLDDGRLTDGQGRTVDFTNTIL IMTSNLGSQFLVQEGLDDAAKRKAVMNAVHAEFKPEFINRLDELVMFHPLSREELGGIVDIQVRQVAARLSDRRISLDVS DSARAWLAEHGYDPVYGARPLRRLVQTEIGDQLARLLLSGKVHDGARVVADCENTSDHVTLKIA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 2e-148 | 44 |
| aec27 | YP_851418.1 | ATPase | Not tested | PAI II APEC-O1 | Protein | 4e-109 | 42 |
| aec27 | AAQ96721.1 | Aec27 | Not tested | AGI-1 | Protein | 3e-109 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpB | YP_003373359.1 | ATP-dependent chaperone protein ClpB | VFG2084 | Protein | 2e-112 | 44 |
| clpB | YP_003373359.1 | ATP-dependent chaperone protein ClpB | VFG2076 | Protein | 1e-119 | 44 |
