Gene Information

Name : tkt (HMPREF0424_0902)
Accession : YP_003374116.1
Strain : Gardnerella vaginalis 409-05
Genome accession: NC_013721
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1027883 - 1029982 bp
Length : 2100 bp
Strand : +
Note : identified by match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232

DNA sequence :
ATGACCGATTTCAACTGGTCTGCATTAGACGAGCGCGCCGTAAAAATGGCGAAGGTTCTCTCGGCTGATGCTGTTGAGCG
AGCAGGACACGGACATCCTGGCTCCCCTGTTTCATTAGCACCGATTGCGTACACATTGTACCAGCATTTCATTAAGCACG
ATCCAGCTGACCCAAAGTGGGCTGGCCGCGATCGTTTTATTCTTTCTGGCGGTCACGCTTCGCTTACGCAATACGTGCAG
TTGTTCTTCTCTGGATACGGCTTGACTCTTGACGATCTCAAGTATTTCCGTGGCGGTGCAGACACGCGTACTCCAGGTCA
CCCAGAATACGGCTTGACTCCAGGCATCGAAATGACTACTGGCCCACTCGGTCAGGGTCTTGCTTCCGCTGTTGGTTTCG
CTTACGGCCAGCGCTTTGAGCGTGGACTTCTCGATCCAGAAGCTCCAGCTGGCACCTCCCCATTCGATCACAAGGTTTGG
GTTATCTGCGGCGAAGGCGACGTTGAGGAAGGCGTTTCTTCTGAAGCTGCTTCCTTGGCTGGAAACCAAAAGCTCGGCAA
TTTGACCGTAATCTTCGATGCAAACCACATTCAGATTGAAGGCGACACTAAGCTCACCTTCTCTGAAGATATTCTTGCTC
GTTACCGTGCATACGGTTGGTACACCGATGAAGTGAGCTTCATCCAGCCAGACGGCTCCTATAAGGAAGACGTTCAGGCT
TTGGCTGCAGCTATTGAAAAGGCTCAGGAAGTTACCGATAAGCCTCACTTCATTAAGGTTAATACTTTGATTGCTTGGCC
AACCCCAGGCAAGACCAACAACGAAGCTTCCCACGGCTCCAAGCTTGGCGAGGAAGCTGTGAAGGGCTTGAAGGAACTTT
GCGGTTTCGACCCAGAAGTTTCGTTCCCAATCGACGAAGAAGCTTTGGCTCACGCTCGCAAGGTTGCAGAGCGCGGCTTG
GCTGCTCACAAGGCTTGGGACGAAGCTCTTGCAAAGTGGGCTGCCGCCAACCCAGATAAGGCTGCTCTTTACGAGCGTCT
TAAGGCTGGCAAGCTTCCTGAAGGCTTCGACAAGGCTATTGACGACTTGGTTGCTGGCTTCGAAGTTGGCTCTAAGGTTG
CTACCCGTAAGGCTTCCGGCGCAGTTCTTAACGCAATTGCTGCTGTTATGCCAGAACTTTGGGGCGGTTCCGCTGATTTG
GGCGGCTCCAATAACACCAACATTAAGGGCGCTGACTCCTTCGGCCCATCCGAAGACGCAACCCGCACTTGGCCAAACGT
TTCCGAGTACGGTCGCCAGCTTCACTTTGGTGTGCGCGAGTTCGCAATGGGTGCTATTACCAACGGCATTTTGCTTGGTT
CTGACACTCGACCATTCAATGGTACATTCTTCCAGTTCTCTGACTACGAGCGTCCAGCAGTTCGCTTGGCTGCTTTGATG
GAGATTCCAAACCTCTACGTTTGGACTCACGACTCTGTAGCCTTGGGCGAAGATGGTCCAACTCACCAGCCAATCGAACA
CTTGGCTGCTTTCCGCGCTATTCCTCAGCTTGAGGTTGTGCGCCCTGCAGATGAGTACGAAACTGCTGAAGCTTACCGTT
ACTTCTTCGAGAAGAAAAACAGCTATCCAACTGCTATGATTTTGACCCGCCAGGGCGTTCCAACCCTCGCTGAGACTGCT
GAAAAGGCTCGCGAAGGCGTGAAGCACGGCGCTTACGTTTTGGTTGATTGCGAAGGCACTCCAGACGTAATCATCATGGC
AACCGGTTCCGAAGTTCAGTGGGCTGTTGCTGGTGCCAAGACTTTGGCTGCTGAAGGCATTAAGGCTCGCGTTCTTTCCA
TGCCATCTCTCGAATGGTTCGAAGAGCAGGACGAAGAGTACAAGGAAGCAATCTTGCCAAAGTCCGTCAAGGCTCGCGTT
TCCATCGAAGCTGGCTTGGCATTGCCTTGGTACAAGTATCTTGGCGATTGCGGCAAGGCTGTTTCTATCGAACAGTACGG
CTTGCAGGGTGACGGCGGTCAGAACATGATTGACTTGGGCATTACTGCTGAGCACGTAGTAGAAGCTGCTAAGGCTTCTA
TCGAAGAAGCTCGCGCCTAA

Protein sequence :
MTDFNWSALDERAVKMAKVLSADAVERAGHGHPGSPVSLAPIAYTLYQHFIKHDPADPKWAGRDRFILSGGHASLTQYVQ
LFFSGYGLTLDDLKYFRGGADTRTPGHPEYGLTPGIEMTTGPLGQGLASAVGFAYGQRFERGLLDPEAPAGTSPFDHKVW
VICGEGDVEEGVSSEAASLAGNQKLGNLTVIFDANHIQIEGDTKLTFSEDILARYRAYGWYTDEVSFIQPDGSYKEDVQA
LAAAIEKAQEVTDKPHFIKVNTLIAWPTPGKTNNEASHGSKLGEEAVKGLKELCGFDPEVSFPIDEEALAHARKVAERGL
AAHKAWDEALAKWAAANPDKAALYERLKAGKLPEGFDKAIDDLVAGFEVGSKVATRKASGAVLNAIAAVMPELWGGSADL
GGSNNTNIKGADSFGPSEDATRTWPNVSEYGRQLHFGVREFAMGAITNGILLGSDTRPFNGTFFQFSDYERPAVRLAALM
EIPNLYVWTHDSVALGEDGPTHQPIEHLAAFRAIPQLEVVRPADEYETAEAYRYFFEKKNSYPTAMILTRQGVPTLAETA
EKAREGVKHGAYVLVDCEGTPDVIIMATGSEVQWAVAGAKTLAAEGIKARVLSMPSLEWFEEQDEEYKEAILPKSVKARV
SIEAGLALPWYKYLGDCGKAVSIEQYGLQGDGGQNMIDLGITAEHVVEAAKASIEEARA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 9e-101 42
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-99 41