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Name : clpC (HMPREF0424_0724) Accession : YP_003373951.1 Strain : Gardnerella vaginalis 409-05 Genome accession: NC_013721 Putative virulence/resistance : Virulence Product : negative regulator of genetic competence ClpC/MecB Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 820852 - 823440 bp Length : 2589 bp Strand : + Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728 DNA sequence : ATGTTTGAACGGTTCACTGATCGCGCACGACGCGTGATTGTGCTAGCTCAGGAAGAGGCTCGCTCACTTCAGCACAATTA TATTGGTACTGAGCATATTTTGCTCGGGCTTATTCGCGAAGGTGAGGGCATTGCCGCGAAAGCGTTAAGCTCAAAAGGCG TAGGCCTAGAAGGCACTCGCAAACAGGTTGAAGAGATGATCGGCAAAGGCACTGTTTCGCCTGCTGGTCATATTCCTTTT ACGCCTCACGCTAAGCAAGTGCTTGAACTGAGTTTGCGCGAAGCTCTTCAGCTTGGTCACAGTTATATTGGTACTGAGCA TATTTTGCTAGGGCTTATACGCGAAGGCGAAGGTGTGGGCACGCAAGTACTTATAAAGATGGAAGTTGATCTTGGAGACT TGCGAAGCACTACTGTTGATTTAATTCGTGGAGATAATGCTCCTAATGGTAGCGAGAAGGGCGAGTTAGCTAATGCTGGA AGTGTGCAAGATAAGCGAAATCAATCCGGCTCTGCTCTTCTTGATCAATTTGGACGCAATTTAACATTTGAAGCTCAAGA AGGAAAGCTTGATCCTGTTATAGGTCGTTCTGAAGAAATTGAACGCGTTATGGTTGTACTTAGCCGACGCACGAAGAATA ATCCTGTGCTTATTGGAGAGCCTGGAGTTGGTAAGACTGCAGTTGTAGAAGGTCTCGCACAGAAAATCGTTGAAGGCGAT GTGCCGGAAACGTTAAAAAATAAGCAAGTTTATTCTCTAGACTTAGGTTCAATGATTGCAGGATCTCGCTACCGTGGCGA TTTCGAAGAGCGCTTGAAAAAAGTGCTTAAAGAAATTAAAACACGCGGCGATATTGTGCTTTTTATTGATGAGATTCACA CTATTGTTGGAGCAGGTTCTGCTGATGGAGCTCTTGGTGCATCCGATATGCTTAAACCAATGCTTGCGCGTGGAGAGCTA CAGACAATTGGTGCTACTACTACTGACGAGTATCGCAAGTATATTGAAAAAGATGCTGCTTTGGAGCGTCGTTTCCAGCC GATTCAAGTTCCAGAACCTACAATTGCTGAAACTATCGAGATTCTTAAAGGATTGCGTTCTCGCTACGAAAATCACCATC ATGTAACTATTACCGATGGAGCTTTACAGTCTTCTGCTGAGCTTTCTGATCGTTACATTCAAGATCGTCACCTTCCAGAT AAGGCTATTGATCTTATTGATGAAGCTGGTGCGCGCTTGCGTATTAAGCGCTTGACTCAGCCGCCTGAGCTCAAAGAATT AAACCATAAGATTGCTAAGATTTCCGAAAAGAAAGATGAAGCAATCAAGCAGCAAGATTTTGAAGAAGCTGCCAATCTTC GCGACGATCAAGAAAAGCTTGAGAATGAAGCTGCAGAGAAGGAAAAGGCTTGGCGCGAAGGCGAGTCTAACGTCAAGATG GTTGTTGATGAAGACATGATTGCTTCCGTTGTTTCGAGCACTACAGGCATTCCTGTAGTAAAGCTTACTCAAGCGGAATC ACAGAAGCTTCTTCAAATGGAATCTGAACTTCACAAGCGTATTGTTGGTCAAGATGAAGCTGTGTCTGCTTTAGCTCGCT CGATTCGTCGTGCTCGAGTTGGTTTGAAGGATCCTAAACGTCCTTCTGGATCGTTTATTTTTGCTGGTCCTACTGGAGTT GGTAAAACTGAGCTTGCCAAGGCGCTTGCAAACTTCTTGTTTGATGACGATAATGCCTTAATCAGAGTTGACATGTCAGA GTTTGCAGAAAAGTATGCTGCGTCTAGGCTTTTCGGTGCTCCTCCTGGATATGTTGGATATGAAGAAGGTGGCGAGCTTA CTGAAAAAGTTCGCAGAAAGCCATTCTCTGTGGTGCTTTTCGACGAGATTGAAAAAGCTCATCCAGATATTTTCAACACG CTTTTGCAAGTACTCGATGACGGTCACTTAACAGACGGTCAGGGTAGAAAAGTGGACTTTAAGAATACGATTATTATTCT TACCACCAATCTTGGTACTCGCGATATTGCGAAGGCTGCAAATACTGGCTTTACACTTGGAAATAACGCTGATTCCACGT ATCAGCGCATGAAAGATCAGGTTAATTCTGAGCTTAAGCGTCATTTCCGTCCAGAGTTCTTAAACCGTTTGGACGACACT ATTGTGTTCCGTCAGCTTACGGAGCCAGAAGTTCGTCAAATTGTTGACATGGACGTGAAGTTGCTTAACGACAGGCTGTT TGATCGTCACATGTCTCTAGAAATTACGGATGCCGCTAAGAATTTGCTTGCACAGAAAGGCTTCGATCCTTTGCTTGGTG CACGTCCGTTGCGTCGCGTAATTCAGCGAGATATTGAGGATACTATTTCTGAAAAGATTTTGCTTGGTGAACTTTCTGAC GGCGAACACATTAAGGTGGATGCTGAAGGCGAAGGATTGCTGGGGGAGTTCACAATTAAAGGCGAAAAGTTTGAGACAAT AGACACAACTGCTGCTGTTGCTACTGAAGAAAATAAGTCTGAAGAAAATAAATCTGAGGATAATAAGTCTGAAGATAGCG AAAAAGAAGATAGCAATAAGAATAAGTAA Protein sequence : MFERFTDRARRVIVLAQEEARSLQHNYIGTEHILLGLIREGEGIAAKALSSKGVGLEGTRKQVEEMIGKGTVSPAGHIPF TPHAKQVLELSLREALQLGHSYIGTEHILLGLIREGEGVGTQVLIKMEVDLGDLRSTTVDLIRGDNAPNGSEKGELANAG SVQDKRNQSGSALLDQFGRNLTFEAQEGKLDPVIGRSEEIERVMVVLSRRTKNNPVLIGEPGVGKTAVVEGLAQKIVEGD VPETLKNKQVYSLDLGSMIAGSRYRGDFEERLKKVLKEIKTRGDIVLFIDEIHTIVGAGSADGALGASDMLKPMLARGEL QTIGATTTDEYRKYIEKDAALERRFQPIQVPEPTIAETIEILKGLRSRYENHHHVTITDGALQSSAELSDRYIQDRHLPD KAIDLIDEAGARLRIKRLTQPPELKELNHKIAKISEKKDEAIKQQDFEEAANLRDDQEKLENEAAEKEKAWREGESNVKM VVDEDMIASVVSSTTGIPVVKLTQAESQKLLQMESELHKRIVGQDEAVSALARSIRRARVGLKDPKRPSGSFIFAGPTGV GKTELAKALANFLFDDDNALIRVDMSEFAEKYAASRLFGAPPGYVGYEEGGELTEKVRRKPFSVVLFDEIEKAHPDIFNT LLQVLDDGHLTDGQGRKVDFKNTIIILTTNLGTRDIAKAANTGFTLGNNADSTYQRMKDQVNSELKRHFRPEFLNRLDDT IVFRQLTEPEVRQIVDMDVKLLNDRLFDRHMSLEITDAAKNLLAQKGFDPLLGARPLRRVIQRDIEDTISEKILLGELSD GEHIKVDAEGEGLLGEFTIKGEKFETIDTTAAVATEENKSEENKSEDNKSEDSEKEDSNKNK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 0.0 | 67 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpC | YP_003373951.1 | negative regulator of genetic competence ClpC/MecB | VFG0079 | Protein | 0.0 | 56 |
| clpC | YP_003373951.1 | negative regulator of genetic competence ClpC/MecB | VFG0080 | Protein | 5e-138 | 49 |
