Gene Information

Name : HMPREF0424_0629 (HMPREF0424_0629)
Accession : YP_003373863.1
Strain : Gardnerella vaginalis 409-05
Genome accession: NC_013721
Putative virulence/resistance : Resistance
Product : copper-exporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.4
Position : 700583 - 702679 bp
Length : 2097 bp
Strand : +
Note : identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525

DNA sequence :
ATGAACAATAACAACAAACATTCATCCCACAGTCACCATAATCATGGCGACATGGATCATTCAAAACATGAGCACGTAAG
CACAGACGAACATGGAGACCATAATAATCAACATCAAGAACATCATGCTGGGCATGATCACAGCGGACACAGTGGGCATG
ACCACCATCATCACGGAAACTTTAAGGAACTTTTCTTAAAATCATTGCCACTAGGAATCATTATTATGCTCTTATCCCCT
ATGGCTGGGTTTGACCTACCATTCCAGTTTACTTTTCCATATTCTGATATTGTAGTAGCTATTTTATCTACTATATTAAT
TATTTATGGTGGACGTCCATTCTATCAAGGGGCAGTTGACGAATTTAAACAAAAAGAACCTGGAATGATGGCTCTCGTAT
CTTTAGGTTTAAGTGTTTCATATTTATATAGTATTTATACTGTAATAGCAAGCTACGTAACAGGTGAACAAATTATGGAT
TTTTTCTTTGAATTTGCTTCATTACTATTAATCATGTTATTAGGTCACTGGATTGAGATGAAAGCTATTGGAGAAGCAGG
AGACGCACAAGCAGAATTGGCTAAGTTAGTGCCGAAAGATGCTCACGTTGTATTAGAAGACGATTCAATTGAAACACGAC
CAGTTGCTGACTTAAAGGTAGGTGATTTAATTCGAGTTCAAGCTGGAGAAAATGTGCCAGCAGATGGAACTATCGAGCGT
GGAGAATCACGTCTAAATGAAGCTCTTTTGACTGGGGAATCAAAAGCAGTTAAAAAAGGTCCTGGCGATGAAGTAATCGG
AGGCTCAACAAATGGGGAAGGGGTTCTTTATATTAAAGTGAATGAGACAGGTGATCAATCCTTCATCTCTCAAGTACAGA
CTTTAATCAGCCAAGCTCAAAGTCAGCCTTCCAGAGCAGAAAATATTGCTCAAAAGGTTGCAGGGTGGCTCTTCTATATT
GCGGTCATTGTCGCACTAATAGCTTTTGTAGTATGGACGCTTATAGCGGACATCCCAACGGCAGTAAAATTTGCTATCAC
AACATTAGTTATAGCTTGTCCTCACGCTTTGGGTCTAGCTATTCCATTGGTAACCGCTCGTAGCACAAGCTTAGGGGCAA
GTCGTGGCTTACTAGTAAAAGACCGAGAATCTTTAGAAATAGCTCAAGATGCAGATGTGATGATTTTAGATAAGACAGGT
ACTTTAACAACAGGTGAGTTTAAAGTATTAGATGTTGAACTTTTTAATGAAAAATATACAAAAGAAGAAATCATTTCACT
ATTGGCAGGTATTGAAGGAGGGTCTAGTCACCCTATTGCTCAATCAATTATAAGTTTCGCCGAGCAGCAAGATATACGTC
CAGTATCTTTTGATTCGATTGATGTAATTTCCGGTGCTGGCGTAGAAGGTAAAGCCAATGGGCACCAATACCAATTAATC
AGTCAAAAAGAATACGGGCGTAATCTAGATATTGATATTCCAAAAGGAGCAACCCTCAGTGTCTTAGTAGAAAACGATGA
TGCCATTGGTGCTGTAGCTTTGGGGGATGAATTAAAAGCAACCAGTAAAGAGTTAATTAAAGCTCTTAAAAATAACAATA
TAGAGCCAATTATGGCAACAGGTGATAATGAAAAAGCGGCTCAAGGCGCGGCAGAAGATTTAGAGATTGAATATAGATCA
AATCAATCTCCACAAGACAAATATGAGTTAGTAAAAACACTTAAAGAAGAAGGAAAAAAAGTTATCATGGTAGGTGACGG
TGTCAATGATGCTCCTTCTCTTGCCTTAGCAGATGTTGGTATAGCTGTAGGTGCTGGAACCCAAGTGGCATTGGATTCAG
CTGATGTCATCTTGACTCAATCTGATCCAGGAGATATTGAATCATTCATTGAATTAGCACACAAAACAACTCGTAAAATG
AAACAAAACCTCTTTTGGGGAGCTGGTTATAACTTTATAGCTATCCCTCTAGCTGCAGGAATTTTGGCCCCTTTTGGTTT
CACATTAAGTCCTGCAGTAGGAGCAATTCTAATGTCTGTGTCAACAGTCATCGTCGCCATTAATGCTATTTTATTAAAAT
TAGATCCGAAAAAATGA

Protein sequence :
MNNNNKHSSHSHHNHGDMDHSKHEHVSTDEHGDHNNQHQEHHAGHDHSGHSGHDHHHHGNFKELFLKSLPLGIIIMLLSP
MAGFDLPFQFTFPYSDIVVAILSTILIIYGGRPFYQGAVDEFKQKEPGMMALVSLGLSVSYLYSIYTVIASYVTGEQIMD
FFFEFASLLLIMLLGHWIEMKAIGEAGDAQAELAKLVPKDAHVVLEDDSIETRPVADLKVGDLIRVQAGENVPADGTIER
GESRLNEALLTGESKAVKKGPGDEVIGGSTNGEGVLYIKVNETGDQSFISQVQTLISQAQSQPSRAENIAQKVAGWLFYI
AVIVALIAFVVWTLIADIPTAVKFAITTLVIACPHALGLAIPLVTARSTSLGASRGLLVKDRESLEIAQDADVMILDKTG
TLTTGEFKVLDVELFNEKYTKEEIISLLAGIEGGSSHPIAQSIISFAEQQDIRPVSFDSIDVISGAGVEGKANGHQYQLI
SQKEYGRNLDIDIPKGATLSVLVENDDAIGAVALGDELKATSKELIKALKNNNIEPIMATGDNEKAAQGAAEDLEIEYRS
NQSPQDKYELVKTLKEEGKKVIMVGDGVNDAPSLALADVGIAVGAGTQVALDSADVILTQSDPGDIESFIELAHKTTRKM
KQNLFWGAGYNFIAIPLAAGILAPFGFTLSPAVGAILMSVSTVIVAINAILLKLDPKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0105 YP_252020.1 hypothetical protein Not tested SCCmec Protein 2e-99 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HMPREF0424_0629 YP_003373863.1 copper-exporting ATPase BAC0383 Protein 0.0 77
HMPREF0424_0629 YP_003373863.1 copper-exporting ATPase BAC0079 Protein 8e-131 50
HMPREF0424_0629 YP_003373863.1 copper-exporting ATPase BAC0629 Protein 2e-98 45