Gene Information

Name : guaA (HMPREF0424_0626)
Accession : YP_003373860.1
Strain : Gardnerella vaginalis 409-05
Genome accession: NC_013721
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 697516 - 699078 bp
Length : 1563 bp
Strand : +
Note : identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888

DNA sequence :
ATGGCAAAAGGACCAGTGCTTGTCGTTGATTTTGGCGCTCAATATGCTCAGCTTATTGCTCGTCGAGTGCGCGAAGCAAA
TGTGTATTCAGAACTTGTTCCTCACTCTATGCCAGTTGACGAGATGCTTGCTAAGGATCCTCAAGCTATTATTCTTTCAG
GCGGTCCTGCTTCTGTTTATGAACCAGGTGCTCCTGACATTGATCCAAAGATTTTTGAAGCAGGTGTACCGGTTCTTGGT
ATTTGCTATGGCTTCCAGGTAATGGCTCATGAGCTTGGTGGCGATGTCGATAAAGCTGCACTTGGTGAGTATGGCAAGAC
TGCTGCAACTATTGATGATTCTGAAGGTTTACTTTCCGGATCTCCATCTGCGCAGAATACTTGGATGAGTCACGGTGTTG
CTGTTAAGCGTGCTCCAGAAGGTTTTACGGTCTTGGCTCACACAGAAGGTGCTCCAGTTGCAGCAATGCAAGACGAAAGT
CGCAAACTTTACGGTGTGCAATGGCATCCAGAAGTTAAACACACTCCATTGGGTCAGGAACTTATATCTACATTCTTACA
TAAGTGTGCAGGACTGAATAATAATTGGAATCCTTCTAACATTATTGAGGATCAAGTTGCTAAGATTCGCGCAGAAGTTG
GGAATGCACAAGTTATTTGTGGTCTTTCTGGTGGCGTAGATTCTGCTGTTGCTGCAGCATTGGTGCATAAAGCAATTGGC
AATCAGCTTACTTGCGTTTTTGTTGACCACGGTTTGCTTCGTAAAGGCGAAGTTGAGCAGGTTAAGCATGATTTTGTTGA
AGCAACAGGCATTAAACTTATTGCAGTTGATGCAGAAGATGACTTTTTGAACGCACTTAAAGGCGTGAGTGAGCCGGAGC
GCAAGCGCAAGATTATTGGCGAAAAGTTTATACGCACTTTTGAAAAAGCTCAGCGTCAAGTTATTGAAGAAGCTGGTAAA
ACTGGAGCTGAAGTTAAGTTCCTTGTGCAAGGCACACTTTACCCGGATGTAGTTGAGTCCGGTGGTGGTGATGGTGCTGC
AAATATCAAATCTCATCACAATGTTGGAGGTTTGCCAAAAGATTTGAAGTTTAAGCTTATTGAACCTTTGCGTACTTTGT
TTAAGGATGAAGTTCGTGCTATTGGAACTGAGCTTGGACTTCCAGATGAAATTGTTTGGCGTCAGCCATTCCCGGGTCCT
GGTTTAGGTATTCGTATTGTGGGTGAGATTACACGCGAACGCTTAGCTGTTCTTCGTGAAGCAGATGCTATTGCGCGCGA
AGAGCTCTCTAAAGCTGGATTGGATCGCGACATTTGGCAATGCCCAGTCGTTTTGCTTGCTGATGTTCATTCTGTTGGTG
TTCAAGGTGATGAGCGCACATATGGTTCTCCAATTGTTTTGCGTCCTGTGAGCTCTGAGGATGCCATGACAGCTGATTGG
TCTCGTGTGCCTTACGATGTATTGGCAAATATTTCTACTCGAATCACGAATGAATGCCGTCAAATTAATCGTGTAGTGCT
CGACGTAACTTCTAAGCCACCTGCCACGATTGAATGGGAGTAA

Protein sequence :
MAKGPVLVVDFGAQYAQLIARRVREANVYSELVPHSMPVDEMLAKDPQAIILSGGPASVYEPGAPDIDPKIFEAGVPVLG
ICYGFQVMAHELGGDVDKAALGEYGKTAATIDDSEGLLSGSPSAQNTWMSHGVAVKRAPEGFTVLAHTEGAPVAAMQDES
RKLYGVQWHPEVKHTPLGQELISTFLHKCAGLNNNWNPSNIIEDQVAKIRAEVGNAQVICGLSGGVDSAVAAALVHKAIG
NQLTCVFVDHGLLRKGEVEQVKHDFVEATGIKLIAVDAEDDFLNALKGVSEPERKRKIIGEKFIRTFEKAQRQVIEEAGK
TGAEVKFLVQGTLYPDVVESGGGDGAANIKSHHNVGGLPKDLKFKLIEPLRTLFKDEVRAIGTELGLPDEIVWRQPFPGP
GLGIRIVGEITRERLAVLREADAIAREELSKAGLDRDIWQCPVVLLADVHSVGVQGDERTYGSPIVLRPVSSEDAMTADW
SRVPYDVLANISTRITNECRQINRVVLDVTSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-171 67
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-140 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-140 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-140 54