Gene Information

Name : glnA_2 (HMPREF0424_1140)
Accession : YP_003374339.1
Strain : Gardnerella vaginalis 409-05
Genome accession: NC_013721
Putative virulence/resistance : Virulence
Product : glutamine synthetase, type I
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : 6.3.1.2
Position : 1317205 - 1318641 bp
Length : 1437 bp
Strand : +
Note : identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653

DNA sequence :
ATGACCACTTTGCAAACTAAAGAAGATGCCGCAGCCCTTATTGAAAAGGAAGGCATTGAGTACGTATCCGTACGATTTAC
TGATTTAATTGGCGTTCAGCAGCACTTTACTGTTCCTGCTGACGAGTTCTTACACAGCGCTTTCACTGATGGAATGGCGT
TCGATGGTTCTTCAATGCAAGGCTTCCAGGCTATTAACGAATCAGATATGAAGCTTATTCCAGATGTTGACACTGCTTAT
ATTGACCCATTCCGTAAGCATAAGACTCTGAATATTGCTTTCTCTATTGTTGACCCTGTAACAGATGAGCCATATTCTAG
GGATCCTCGTCAGGTCGCTATTAAAGCAGAATCCTATTTGAAATCAACTGGCATTGCTGACACTGCAAGCTTTGCCCCTG
AAGCTGAGTTCTTCATCTTTGACAAGGTGCGTTTTGCTAACGACATGCAGCGCTCCTTCTATGAGGTTGATTCTAACGAA
GCTCCTTGGAATTCTGGCATCGACACTGAAGATGACGGTAGCAACAATATTGGTTTTAAGAATCGAGTAAAGCACGGCTA
CTTCCCTGTGCCACCAGTAGATCACAATCAGGATTTGCGCGATGACATGGTTTACAACTTGCAAAAAGTTGGTTTGATTC
TTGAGCGTTCTCACCACGAAGTCGGCGGCGCAGGTCAGCAGGAAATCAACTACCGTTACAATACGCTTGTTCATGCTGGC
GATGATTTGATGAAATACAAGTATGTGGTTCATGAAACTGCTGCTTTAGCTGGTAAGGCTGCAACATTTATGCCAAAGCC
AATTGCTGGAGATAACGGCACTGGCATGCACTGCCATCAGTCGCTTTGGAAAGATGGCAAGCCATTGTTCTATGCGGAAA
CTGGCTACGCTCAACTTTCTGATATTGCACGTTGGTACATTGGCGGCTTGATTAAGCACGCTTCTTCTGTGCTTGCATTT
ACGAATCCTTCGCTTAACTCTTACCATCGCTTGGTTCCAGGATACGAAGCTCCAGTCAACTTGGTTTACTCTGCTCGTAA
CCGTTCTGCAGCTATTCGTATCCCTCTTGCTGGTACAGAACCTGCTGCTAAGCGTATTGAGTTCCGTGCACCGGATCCTT
CATGCAACCCATTCTTAGCATTCTCCGCTCAGCTTATGGCAGGTTTGGATGGTGTTATTAACCATATTGAGCCTCCTGCC
CCTGTTGATAAAGATTTGTACGAGCTTCCTCCAGAGGAGCATGACGGCATTAAGCAAGTTCCTTCTTCGCTTGGTGAAGC
TTTGCAATCTTTGGAAGAGGATCACGACTTCCTTATGCAAGGCGACGTATTTACTAGCGACTTGATTGAAACTTGGCTGA
ATTTGAAGCATGAGGAAATGGATATGGCTCGCTTGGCTCCAACTCCACTCGAGTATGAGCTTTACTTCCACATCTAA

Protein sequence :
MTTLQTKEDAAALIEKEGIEYVSVRFTDLIGVQQHFTVPADEFLHSAFTDGMAFDGSSMQGFQAINESDMKLIPDVDTAY
IDPFRKHKTLNIAFSIVDPVTDEPYSRDPRQVAIKAESYLKSTGIADTASFAPEAEFFIFDKVRFANDMQRSFYEVDSNE
APWNSGIDTEDDGSNNIGFKNRVKHGYFPVPPVDHNQDLRDDMVYNLQKVGLILERSHHEVGGAGQQEINYRYNTLVHAG
DDLMKYKYVVHETAALAGKAATFMPKPIAGDNGTGMHCHQSLWKDGKPLFYAETGYAQLSDIARWYIGGLIKHASSVLAF
TNPSLNSYHRLVPGYEAPVNLVYSARNRSAAIRIPLAGTEPAAKRIEFRAPDPSCNPFLAFSAQLMAGLDGVINHIEPPA
PVDKDLYELPPEEHDGIKQVPSSLGEALQSLEEDHDFLMQGDVFTSDLIETWLNLKHEEMDMARLAPTPLEYELYFHI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 1e-82 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA_2 YP_003374339.1 glutamine synthetase, type I VFG1399 Protein 1e-143 62