Gene Information

Name : Psta_3654 (Psta_3654)
Accession : YP_003372174.1
Strain : Pirellula staleyi DSM 6068
Genome accession: NC_013720
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 4770745 - 4771887 bp
Length : 1143 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: rce:RC1_1986 cystathionine gamma-synthase (CGS) (O-succinylhomoserine(thiol)-lyase)

DNA sequence :
ATGAAATTTCGTACCCGCGCGATTCATGTCGGAGTGCATCGCGATGCAGCGACCGGCGCCGTGGTTCCACCGATTCATCT
CGCGTCAACATTTGTGCAACCAGGCGCGGGTGTGTGGGGCGAGTTTGATTACTCGCGTAGTGGCAATCCAACTCGCAAAG
GTTTTGAGACCACGATTGCCTCGCTGGAGTCGGGCATCGGAGGACTCGCTTTCGCCTCGGGCATGGCAGCAACTCACACC
GCTGTGATGCTGCTGAGCGCTGGCGATCACATTCTGGCGGGGCGCGATATTTACGGCGGAACCTATCGCCTGCTGCATCG
CGTGGTCGATCGCTACAACGTGAAAGTTTCACTCGTCGACACCACGGATCTGGCTGCTGTCGCCGCCGCGATTCGTCCCG
AGACCAAAATGCTGTGGCTCGAGTCGCCCGGCAATCCGCAGATGTCGATCACCGATCTCGAGGCCGTTTCAAAACTCGCC
CACGAGCGCGGATTACTCGTGGGGGTCGATAGCACATTTGCCACGCCAGTCCTGACACGTCCGCTGGAACTGGGGGCCGA
TATCGTGATGCATTCGGCCACAAAGTACATCGGCGGTCACAGCGACTTGCTTGGTGGTGTGCTGGTGGTGAAAGATAAGG
CGCTCCTCGATCGGCTCTACTTCTTGCAAAACGCCACTGGCAACGTCATGGGGCCGCTCGAGTGTTTTCTCGCGAGCCGC
GGGCTGAAAACGCTCGAGCTACGCGTGCTCGAGCAGTCGCGTACGGCTATGAAGATTGCGAATTGGTTGCTCGCTGATCC
TCGTATTTCTCGCGTGCTGTACCCTGGCTTGCCGGGGCATCCGGGGCACGAAATTGCCGCGCGTCAGATGACCGGCGGTT
TCGGCGCGATGCTCACGTTTGAAGTACGCGGCGATCTTGAAAAAACTAAACGCGTTTGTCAGGCCACGCAGTTGTTCCAG
TTAGCGGTGAGCCTGGGGGCTGTGGAGTCGCTGATCGAACAGCCTGCCAGCATGTCGCACGCCAGCTACAGCGCCGAAGC
GCGGGCTGCTAACGGAATCACCGATGGACTGATTCGCTTATCGGTCGGGCTCGAGGATGCGGACGACTTAATCGCCGATC
TCGATCAAGCGCTGAATGCGTAA

Protein sequence :
MKFRTRAIHVGVHRDAATGAVVPPIHLASTFVQPGAGVWGEFDYSRSGNPTRKGFETTIASLESGIGGLAFASGMAATHT
AVMLLSAGDHILAGRDIYGGTYRLLHRVVDRYNVKVSLVDTTDLAAVAAAIRPETKMLWLESPGNPQMSITDLEAVSKLA
HERGLLVGVDSTFATPVLTRPLELGADIVMHSATKYIGGHSDLLGGVLVVKDKALLDRLYFLQNATGNVMGPLECFLASR
GLKTLELRVLEQSRTAMKIANWLLADPRISRVLYPGLPGHPGHEIAARQMTGGFGAMLTFEVRGDLEKTKRVCQATQLFQ
LAVSLGAVESLIEQPASMSHASYSAEARAANGITDGLIRLSVGLEDADDLIADLDQALNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-73 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-74 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-51 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Psta_3654 YP_003372174.1 cystathionine gamma-lyase BAC0207 Protein 6e-62 45