Gene Information

Name : ROD_49731 (ROD_49731)
Accession : YP_003368339.1
Strain : Citrobacter rodentium ICC168
Genome accession: NC_013716
Putative virulence/resistance : Virulence
Product : adhesin autotransporter
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3468
EC number : -
Position : 5224334 - 5227180 bp
Length : 2847 bp
Strand : -
Note : similar to E. coli autotransporter adhesin involved in diffuse adherance (AIDA-I), and TibA

DNA sequence :
ATGAAACGACATCTGAACACCAGCTACAGGCTGGTATGGAATCACATTACGGGCACCCTGGTGGTGGCTTCCGAACTGGC
CCGCTCACGGGGAAAACGCACCGGTGTGGCGGTTGCTCTGTCTTTTGCTGCTGTCACGTCAGTCCCGGCACTGGCTGCTG
ACACAGTTGTACAGGCGGGAGAAACCGTGAGCGGCGGAACACTGGCAAATCATGACAACCAGATTGTCTTCGGTACGACC
AACGAAATGACCATCAGTACCGGGCTGGAGTATGGGCCGGATAACGAGGCCAATACCGGCGGACAATGGATACAAAATGG
CGGTACCGCCAACAACACTACTGTCACCGGTGGTGGTCTTCAGAGAGTGAATGCCGGAGGAAGCGTTTCAGACACGGTTA
TCAGTGCCGGAGGCGGACAGAGCCTTCAGGGGCAGGCACTGAACACCACTCTGAACGGCGGTGAGCAGTGGGTACATGAA
GGCGGGATTGCAACGGGCACCGTCATTAATGAGAAGGGCTGGCAGGTCGTCAAACCCGGCGCAGTGGCAACCGACACGGT
TGTGAATACCGGCGCGGAAGGGGGACCGGATGCAGAAAATGGTGATACCGGGCAGTTTGTTCGCGGAGATGCCGTACGTA
CCACTATCAATGAAAATGGTCGTCAGATTGTGGCTGCTGAAGGAACAGCAAATACCACTGTGGTTTATGCTGGCGGCGAC
CAGACTGTACACGGACATGCGCTGGATACCACGCTGAATGGGGGGTATCAGTATGTGCACAACGGCGGTACGGCGTCTGG
CACTGTTGTAAACAGTGACGGCTGGCAGATTATCAAGGAAGGTGGTCTGGCGGATTTCACCACCGTTAACCAGAAAGGCA
AACTGCAGGTGAACGCCGGTGGTACAGCCACGAATGTCACCCTGAAGCAGGGAGGCGCACTGGTCACCAGTACGGCGGCA
ACCGTCACCGGCAGCAACCGTCTGGGCAATTTCACGGTGGAAAACGGTAATGCTGACGGTGTTGTACTGGAGTCCGGTGG
TCGCCTGGATGTACTGGAGGGCCATTCAGCCTGGAAAACACTGGTGGATGACGGCGGTACCCTGGCAGTGTCTGCCGGTG
GTAAAGCAACAGATGTCACCATGACATCCGGTGGTGCCCTGATTGCAGACAGTGGTGCCACTGTTGAGGGGACCAATGCC
AGCGGTAAGTTCAGTATTGATGGCATATCCGGTCAGGCCAGCGGCCTGCTGCTGGAAAATGGTGGCAGCTTTACGGTTAA
TGCCGGGGGACAGGCTGGCAACACCACTGTCGGACATCGTGGAACACTGACGCTGGCTGCCGGGGGAAGTCTGAGTGGCA
GAACACAGCTCAGTAAAGGCGCCAGTATGGTACTGAATGGTGATGTGGTCAGTACCGGCGATATTGTTAACGCAGGAGAG
ATTCACTTTGATAATCAGACGACACCGGATGCCGCGCTGAGCCGTGCTGTTGCAAAAGGCGACTCCCCGGTAACGTTCCA
TAAACTGACCACCAGTAACCTCACCGGTCAGGGTGGCACCATCAATATGCGTGTTCGCCTTGATGGCAGCAATGCCTCTG
ACCAGCTGGTGATTAATGGTGGTCAGGCAACCGGCAAAACCTGGCTTGCGTTTACAAATGTCGGAAACAGTAACCTCGGG
GTGGCAACCTCCGGACAGGGTATCCGGGTTGTGGATGCACAGAATGGTGCCACCACAGAAGAAGGTTCGTTTGCCCTGAG
TCGCCCGCTTCAGGCCGGCGCCTTTAACTACACCCTGAACCGTGACAGAGATGAAGACTGGTACCTGCGCAGTGAAAATG
CTTATCGTGCTGAAGTCCCCCTGTATGCCTCCATGCTGACACAGGCAATGGACTATGACCGGATTCTGGCAGGCTCCCGC
AGCCATCAGACCGGTGTAAACGGTGAAAATAACAGCGTCCGTCTCAGCATTCAGGGCGGTCATCTCGGTCACGATAACAA
CGGCGGTATTGCCCGTGGGGCCACGCCGGAAAGCAACGGCAGCTATGGCTTCGTCCGTCTGGAGGGTGACCTGCTGAGAA
CAGAGGTTGCCGGTATGTCTGTGACCGCGGGGGTATATGGTGTTGCTGGCCATTCTTCCGTTGATGTTAAGGATGATGAC
GGCTCCCGCGCCGGCACGGTCCGGGATGATGCCGGCAGTCTGGGCGGATACCTGAATCTGGTACACACGTCCTCCGGCCT
GTGGACTGACATTGTGGCACAGGGAACCCGCCACAGCATGAAAGCGTCATCGGACAATAACGACTTCCGCGCCCGGGGCT
GGGGCTGGCTGGGCTCACTGGAAACCGGTCTGCCCTTCAGTATCACTGACAACCTGATGCTGGAGCCACAACTGCAGTAT
ACCTGGCAGGGACTTTCCCTGGATGACGGCCAGGATAACGCCGGTTATGTGAAGTTCGGGCATGGCAGTGCACAACATGT
GCGTGCCGGCTTCCGTCTGGGCAGCCACAACGATATGAACTTTGGTAAAGGCACCTCATCCCGTGACACCCTGCGCGACA
GTGCAAAACACAGTGTGCGTGAACTGCCGGTGAACTGGTGGGTACAGCCTTCTGTTATCCGCACCTTCAGCTCCCGGGGG
AACATGAGCATGGGTACAGCCGCAGCCGGCAGTAACATGACGTTCTCACCGTCCCGGAATGGCACGACACTGGACCTGCA
GGCCGGACTGGAAGCCCGTGTCCGGGAAAATATCACCCTGGGCGTTCAGGCCGGTTATGCCCACAGTGTCAGCGGCAGCA
GCGCTGAAGGTTATAACGGTCAGGCCACGCTGAATGTGACTTTCTGA

Protein sequence :
MKRHLNTSYRLVWNHITGTLVVASELARSRGKRTGVAVALSFAAVTSVPALAADTVVQAGETVSGGTLANHDNQIVFGTT
NEMTISTGLEYGPDNEANTGGQWIQNGGTANNTTVTGGGLQRVNAGGSVSDTVISAGGGQSLQGQALNTTLNGGEQWVHE
GGIATGTVINEKGWQVVKPGAVATDTVVNTGAEGGPDAENGDTGQFVRGDAVRTTINENGRQIVAAEGTANTTVVYAGGD
QTVHGHALDTTLNGGYQYVHNGGTASGTVVNSDGWQIIKEGGLADFTTVNQKGKLQVNAGGTATNVTLKQGGALVTSTAA
TVTGSNRLGNFTVENGNADGVVLESGGRLDVLEGHSAWKTLVDDGGTLAVSAGGKATDVTMTSGGALIADSGATVEGTNA
SGKFSIDGISGQASGLLLENGGSFTVNAGGQAGNTTVGHRGTLTLAAGGSLSGRTQLSKGASMVLNGDVVSTGDIVNAGE
IHFDNQTTPDAALSRAVAKGDSPVTFHKLTTSNLTGQGGTINMRVRLDGSNASDQLVINGGQATGKTWLAFTNVGNSNLG
VATSGQGIRVVDAQNGATTEEGSFALSRPLQAGAFNYTLNRDRDEDWYLRSENAYRAEVPLYASMLTQAMDYDRILAGSR
SHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESNGSYGFVRLEGDLLRTEVAGMSVTAGVYGVAGHSSVDVKDDD
GSRAGTVRDDAGSLGGYLNLVHTSSGLWTDIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQLQY
TWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDMNFGKGTSSRDTLRDSAKHSVRELPVNWWVQPSVIRTFSSRG
NMSMGTAAAGSNMTFSPSRNGTTLDLQAGLEARVRENITLGVQAGYAHSVSGSSAEGYNGQATLNVTF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAE85197.1 antigen43 protein orthologue Not tested PAI V 536 Protein 0.0 97
unnamed AAL08472.1 putative autotransporter Not tested SRL Protein 0.0 95
Z1211 NP_286746.1 adhesin Not tested TAI Protein 0.0 88
Z1651 NP_287154.1 adhesin Not tested TAI Protein 0.0 88
aec67 AAW51750.1 Aec67 Not tested AGI-3 Protein 0.0 65
S3195 NP_838479.1 outer membrane fluffing protein Not tested SHI-1 Protein 0.0 64
aidA ADD91708.1 AidA Not tested PAI-I AL862 Protein 0.0 60
sap AAK00474.1 Sap Not tested SHI-1 Protein 0.0 60
SF2991 NP_708765.1 outer membrane fluffing protein Not tested SHI-1 Protein 0.0 60
flu CAI43838.1 antigen 43 Not tested LEE Protein 0.0 58
unnamed CAD66200.1 hypothetical protein Virulence PAI III 536 Protein 0.0 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ROD_49731 YP_003368339.1 adhesin autotransporter VFG1063 Protein 0.0 95
ROD_49731 YP_003368339.1 adhesin autotransporter VFG0655 Protein 0.0 60
ROD_49731 YP_003368339.1 adhesin autotransporter VFG1675 Protein 0.0 56