Gene Information

Name : cts2V (ROD_34231)
Accession : YP_003366884.1
Strain : Citrobacter rodentium ICC168
Genome accession: NC_013716
Putative virulence/resistance : Virulence
Product : T6SS protein Cts2V
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3603847 - 3606354 bp
Length : 2508 bp
Strand : +
Note : ClpV component of T6SS

DNA sequence :
ATGGACTTAAAAGCGCTGGTACAGCGGCTGAACCCGGTTTGTCTGTACGCGCTGGAACAGGCCGCCGGGCGTAGCCGGGC
GCAGGGGCACTGGTTTGTGGAGCCGGAACATCTGCTGCTGGCATTGCTGGACGACGAGCACTGCGATCTGGCGTGCTGCC
TTGACGGCGCGGGGATTCCTGTCGACGCGCTGCGCGATGAGATCCGGCGCGCCCAGTCGCAGTTCAGAACCGGCTGTACG
CGAATGCCGGTCTTTTCTGCGCAGTTGGTGGAGCTGCTGGAGGGGGCGCTGTTACTGACCACTTTCCGTCAGTTGAAGCA
GGTGCGCTCCGCGCTGCTGCTGCTGACTCTGCTCACCCGCGATCGCCTGCGCGCCCAGTTGGCGCAGGGGCTACCGCTGC
TGTTAAAGATCTCCGCAGAACAACTGGAAGATCATTGGCTGAATTGGTGTCGTGGATCCGCTGAAGCGGTGAGCGATAGA
TCGGACGCTGACGCGGCGGTTCGCGGCGACAGCGTGCTGGATCAATACACACACGATCTTACCCGTGAAGCCCGGCAAGG
ACGGATCGACCCGATCATCGGGCGTGATGCTGAAATCCGTCAGTGCATTGACATTCTGCTGCGCCGTCGGCAGAACAACC
CGATTCTGGTAGGCGCGCCGGGCGTCGGGAAAACCGCCGTCGCCGAAGGGCTGGCGCTGCGTATCGCCGAAGGCAGCGTG
CCGCCGCCTCTGCGTGATGTGGCGCTGCTTTCACTCGATCTCGGCCTGTTACAGGCGGGGGCGGGAGTGAAAGGCGAATT
TGAGCAGCGCCTGAAAGGGGTGATTGAGGCGGTCAAAAAATCCTCTCAGCCGATCGTCTTGTTTATCGACGAAGCCCATA
CGCTGATTGGCGCAGGCGGCGCCGAGGGCGGCAGCGATGCCGCCAACCTGCTGAAGCCAGCGCTGGCGCGTGGCGAGCTG
CGAACCATTGCCGCTACCACCTGGCAGGAGTACAAAAAATATTTTGAGAAGGACCCGGCGCTGGATCGCCGTTTTCAGCG
CATTCATATTGAAGAGCCGGACGAGGATAGCGCGGTGATGATGCTGCGGGCGGTGGCCGATAAGCTGGAAGCGCACCACG
GGGTGCAGATTCTGGATACCGCTATTCGAGAGGCGGTGCGCCTGTCGCAACGCTACATCTCCGGGCGTCAGCTACCGGAT
AAGGCTATCAGCGTCCTTGATACCGCCTGTTCGCGGGTGGCGCTGGCGCAGCATGATATCCCTCCGGCGTTGGAGGAGGT
TCGCCAGCAGCTGGCTACCATTGAGGAAGAGAGCGTGCGTCTGAATCGCGAGCTGCTGGTGGGCATCGATCATCACGATC
GGCTATGCGATCTGGAGGCGCAGGCGAAGCTGTTGCAGCTTCAGGCGCAGGAGGTGGAGGAACGCTGGCAGGATGAACGC
CAGCGGGTCGGCGAACTGCTGGCTGCCCGTCAACGGATGCTGGCGCTGAACGCGCGGCTGGACGACGAGGAAGAACTGGA
ACAGGAGCTGGTGGAGTGCGCGGCACTGATCGGCAAACTGGAAACCGCCGCCGTCCAACTCCGCGATGAAGTGCCGCTGG
TACCAGACTGCGTTGATGCCGCCACCGTTGCAGCAGTGATCGGCGGCTGGACCGGGATACCGATCGGGCAGATGCTTACT
GATGAAGCGCACGCGCTGCGTACGCTGGTCGAACGGATGAGCGAGCGGGTGATGGGGCAACGGGCAGCGCTTGAGACTAT
CGCCCGGCGGCTGCGCGCCTACCGCAGCGGCCTGACCGATCCGCAAAAGCCGGTTGGCGTATTCCTGCTGGTGGGGCCAA
CCGGCGTTGGCAAAACTGAAACCGCCTATGCGCTGGCCGATGCGCTCTACGGCGGCGAACGAAATCTCATCACCATCAAC
CTCTCCGAATACCAGGAAGCGCACACCGTCAGCCAGTTAAAAGGCGCGCCGCCGGGTTACGTCGGCTATGGCAGCGGTGG
GGCGCTAACTGAAGCCGTGCGCCGCCGTCCTTACTCTGTGGTTCTGCTGGATGAAATCGAAAAGGCGCATCCGGACGTGC
TGGAGGCGTTTTATAACGTCTTCGACAAAGGCGTCATGGAGGACGGTACCGGATTAATTGTCGACTTCAAAAACACGGTG
ATGCTGGCGACCAGCAACGTCGGGGCGGAGTTAATTCTTGAAACGCCGACTTCTGAATTCAATAGCGAGTGGTTTAATAC
GGCGATGCGCGAAGAGTTGTTGCGCCATTTTCGTCCGGCGTTTTTAGCGAGGATGACCACAGTAGCCTATCGCGCGTTGG
ATGAAGAAACATTAAAAGGCATTGTGCTGGCGAAACTGGAGAAATTAGCTCAACGGTATCTGGTGGCGACAGGTGAGAAA
TTAAATATGGAGGATGGGCTGGTCGAAAGGGTAATGGATCAATGTAAGGGAGTGGGGGCCAGAGATATTGAGAATCTGGT
GATTGGGGCAGTAATGGGCGATAAATAA

Protein sequence :
MDLKALVQRLNPVCLYALEQAAGRSRAQGHWFVEPEHLLLALLDDEHCDLACCLDGAGIPVDALRDEIRRAQSQFRTGCT
RMPVFSAQLVELLEGALLLTTFRQLKQVRSALLLLTLLTRDRLRAQLAQGLPLLLKISAEQLEDHWLNWCRGSAEAVSDR
SDADAAVRGDSVLDQYTHDLTREARQGRIDPIIGRDAEIRQCIDILLRRRQNNPILVGAPGVGKTAVAEGLALRIAEGSV
PPPLRDVALLSLDLGLLQAGAGVKGEFEQRLKGVIEAVKKSSQPIVLFIDEAHTLIGAGGAEGGSDAANLLKPALARGEL
RTIAATTWQEYKKYFEKDPALDRRFQRIHIEEPDEDSAVMMLRAVADKLEAHHGVQILDTAIREAVRLSQRYISGRQLPD
KAISVLDTACSRVALAQHDIPPALEEVRQQLATIEEESVRLNRELLVGIDHHDRLCDLEAQAKLLQLQAQEVEERWQDER
QRVGELLAARQRMLALNARLDDEEELEQELVECAALIGKLETAAVQLRDEVPLVPDCVDAATVAAVIGGWTGIPIGQMLT
DEAHALRTLVERMSERVMGQRAALETIARRLRAYRSGLTDPQKPVGVFLLVGPTGVGKTETAYALADALYGGERNLITIN
LSEYQEAHTVSQLKGAPPGYVGYGSGGALTEAVRRRPYSVVLLDEIEKAHPDVLEAFYNVFDKGVMEDGTGLIVDFKNTV
MLATSNVGAELILETPTSEFNSEWFNTAMREELLRHFRPAFLARMTTVAYRALDEETLKGIVLAKLEKLAQRYLVATGEK
LNMEDGLVERVMDQCKGVGARDIENLVIGAVMGDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-129 53
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 6e-110 44
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 8e-110 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cts2V YP_003366884.1 T6SS protein Cts2V VFG2076 Protein 6e-152 51
cts2V YP_003366884.1 T6SS protein Cts2V VFG2084 Protein 6e-116 48