Gene Information

Name : escV (ROD_29941)
Accession : YP_003366503.1
Strain : Citrobacter rodentium ICC168
Genome accession: NC_013716
Putative virulence/resistance : Virulence
Product : T3SS structural protein EscV
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 3166028 - 3168055 bp
Length : 2028 bp
Strand : -
Note : -

DNA sequence :
ATGAATAAACTCTTAAATGTATTTGAAAAAGTAGAGTCATATCACGATCTTATTCTGGCTCTCTTCTTCTTTATGGCTGT
AATGATGATGATTATTCCACTGCCAACAGTTGTGGTGGATATCATTATCGCGATTAATATCTCGACAGCTTTACTTTTAT
TAATGCTCTCAATCTATATAAAAAATCCTCTTGAGCTAACTTCTTTTCCAACAATTCTGTTGATTACGACGTTGATGCGC
CTGTCACTCAGTGTCAGTACCACCAGACTTATTCTTTTGCATCATGATGCGGGTGACATTATTTACTCCTTCGGTAACTT
TGTTGTTGGCGGTAACATTGTTGTTGGCCTGGTTATTTTTACAATTATCACCATTGTACAATTTATGGTTATTACAAAAG
GGGCTGAGCGCGTTGCTGAAGTGAGTGCTCGTTTCTCCCTGGATGGTATGCCAGGGAAACAAATGAGTATTGATGGTGAT
ATGCGTGCAGGCGTTATCGATCCGCTTGAGGCAAAAGTTCTTCGTTCCCGTGTACAAAAAGAAAGCCAGTTCTATGGCTC
AATGGACGGGGCGATGAAGTTTGTAAAAGGGGACGCTATCGCTGGTATCATCATTGTTTTAGTTAACTTGTTTGGTGGCG
TTCTCATTGGTATGTGGCAGTTTGACATGCCATTTAGTGAGGCACTTAGCCTGTTTTCTGTATTGTCGGTTGGTGATGCC
CTGGTTGCTCAGATCCCTGCGCTTATTATTTCTGTAACTGCGGGGGTGGTTGTTACTCGTGTTCCCGGTGAAAGCGAAAA
AGAAGAAAACCTTGCAGGGGATATTATTCAGCAAGTTTCTGTTAATAGTCGTCCATTTTTGATCAGTGCTGCATTGATGC
TTGTAATGGCGATTATCCCTGGTTTTCCTACGTTGGTCTTCTTGTTTTTGGCCGTTTGTTTGCTGGGTATTGCCTGGAAA
TTGCAGAAAAAAAGAGCATTTGGATCTACCAATAGTAAAGATTCGCTGGGAGGCGATTTGTCGAATAGCCAAAATGTCTC
TCCAGGCGCCGAGCCATTAATTTTAAACTTAAGTAATAATATTTATAGTGCAGATATTACACAGCAAATTGAGGTTGTAC
GTTGGGGTTTCTTTGAAGAAAGTGGAATCCCATTGCCTAAGATTATTGTTAATCCGATAAAAAATAATGATAGTGTAGTG
GAATTTTTGCTCTATCAAGAGTCAATATACAAAGATACACTGACCAAAGATACTGTTTATTTTGAAGCCGGACACGGAGA
TATATCATTTGAGTTTGTTCAGGAAAAAATTTCGATTAACTCTATCGTATATAAAACGAATGAGGCTAACCAACAGCTAG
CTCATCTTTCAGGTATGAATGTGTATTCAGAAACAAATGATAAGATAACATTTTTGTTAAAGAAACTTGTATTATCTAAC
GCCAAAGAGTTTATTGGTGTACAAGAAACTCGTTATCTGATGGACATCATGGAGAGAAAATATAACGAGCTTGTGAAAGA
ACTCCAACGCCAGCTTGGTCTGAGCAAAATTGTCGACATTCTTCAGCGGCTTGTAGAGGAAAATATCTCAATTAGAGATC
TTCGAACTATCTTTGAGACACTTATCTTTTGGTCAACAAAAGAAAAAGATGTGGTTATCTTATGTGAATACGTTCGTATT
GCTCTCCGTCGGCATATTTTAGGCCGCTATAGTGTTCGTGGTACTATTCTGAATGTTTGGCTTATAGGTTCTGATATTGA
AAATGAGCTGCGGGAGTCGATTAGACAAACGTCATCAGGTTCGTATCTGAATATCTCCCCGGAACGGAGTGAGCAGATAA
TTGGCTTCTTGAAAAATATCGTGAATCCAACGAGTAACGGCGTCATTCTGACCGCTTTAGATATCAGGCGTTATGTGAAG
AAAATGATTGAAGGTTCGTTCCCGTCAGTACCCGTGCTCTCTTTTCAGGAAGTTGGTAATAATATCGAACTGAAAGTATT
AGGAACGGTAAATGATTTCAGAGCATAA

Protein sequence :
MNKLLNVFEKVESYHDLILALFFFMAVMMMIIPLPTVVVDIIIAINISTALLLLMLSIYIKNPLELTSFPTILLITTLMR
LSLSVSTTRLILLHHDAGDIIYSFGNFVVGGNIVVGLVIFTIITIVQFMVITKGAERVAEVSARFSLDGMPGKQMSIDGD
MRAGVIDPLEAKVLRSRVQKESQFYGSMDGAMKFVKGDAIAGIIIVLVNLFGGVLIGMWQFDMPFSEALSLFSVLSVGDA
LVAQIPALIISVTAGVVVTRVPGESEKEENLAGDIIQQVSVNSRPFLISAALMLVMAIIPGFPTLVFLFLAVCLLGIAWK
LQKKRAFGSTNSKDSLGGDLSNSQNVSPGAEPLILNLSNNIYSADITQQIEVVRWGFFEESGIPLPKIIVNPIKNNDSVV
EFLLYQESIYKDTLTKDTVYFEAGHGDISFEFVQEKISINSIVYKTNEANQQLAHLSGMNVYSETNDKITFLLKKLVLSN
AKEFIGVQETRYLMDIMERKYNELVKELQRQLGLSKIVDILQRLVEENISIRDLRTIFETLIFWSTKEKDVVILCEYVRI
ALRRHILGRYSVRGTILNVWLIGSDIENELRESIRQTSSGSYLNISPERSEQIIGFLKNIVNPTSNGVILTALDIRRYVK
KMIEGSFPSVPVLSFQEVGNNIELKVLGTVNDFRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAL06368.1 EscV Virulence LEE Protein 0.0 99
escV AAL57541.1 EscV Virulence LEE Protein 0.0 96
escV YP_003223476.1 translocator EscV Virulence LEE Protein 0.0 96
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 0.0 96
escV CAC81861.1 EscV protein Virulence LEE II Protein 0.0 96
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 0.0 96
escV CAI43875.1 EscV protein Virulence LEE Protein 0.0 96
escV AAK26714.1 EscV Virulence LEE Protein 0.0 96
escV NP_290269.1 hypothetical protein Virulence LEE Protein 0.0 95
escV AAC31514.1 L0035 Virulence LEE Protein 0.0 95
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 0.0 95
escV ACU09459.1 EscV protein Virulence LEE Protein 0.0 95
escV AAC38382.1 EscV Virulence LEE Protein 0.0 95
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 0.0 79
escV AFO66414.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 0.0 79
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 4e-124 49
ssaV NP_460379.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 1e-132 49
ssaV YP_216422.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 2e-132 49
ssaV CAA70536.1 secretion system apparatus Virulence SPI-2 Protein 1e-132 49
ssaV NP_456114.1 putative type III secretion protein Virulence SPI-2 Protein 4e-132 48
ssaV NP_805085.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 4e-132 48
lssD AAO18050.1 LssD Virulence TTSS locus Protein 2e-114 43
ECs3731 NP_311758.1 EivA Not tested LIM Protein 3e-96 41
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 2e-94 41
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 2e-94 41
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 2e-94 41
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 2e-94 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
escV YP_003366503.1 T3SS structural protein EscV VFG0729 Protein 0.0 95
escV YP_003366503.1 T3SS structural protein EscV VFG0813 Protein 0.0 95
escV YP_003366503.1 T3SS structural protein EscV VFG0514 Protein 6e-133 49
escV YP_003366503.1 T3SS structural protein EscV VFG0384 Protein 1e-111 43
escV YP_003366503.1 T3SS structural protein EscV VFG1006 Protein 1e-99 42
escV YP_003366503.1 T3SS structural protein EscV VFG0064 Protein 9e-111 42
escV YP_003366503.1 T3SS structural protein EscV VFG0198 Protein 5e-103 42
escV YP_003366503.1 T3SS structural protein EscV VFG1780 Protein 4e-100 41
escV YP_003366503.1 T3SS structural protein EscV VFG0557 Protein 1e-94 41