Gene Information

Name : tir (ROD_29851)
Accession : YP_003366495.1
Strain : Citrobacter rodentium ICC168
Genome accession: NC_013716
Putative virulence/resistance : Virulence
Product : Tir, translocated intimin receptor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3159159 - 3160802 bp
Length : 1644 bp
Strand : -
Note : -

DNA sequence :
ATGCCTATTGGTAATCTTGGTAATAATAATATAAGTAACAATTTAATTCCGCCTGCGCCGCCACTACCGTCACAAACAGA
CGGCGCGACAAGGGGGAATGGTAGTAGTCTTATTAGCTCTACAGGATCATTGGGATCTCGTTTATTATTTTCTCCCCTGA
GAAGTTCTATCGTTGATACTGTTGATTCCAGAGATGTTCCAGGGCTTCCTGAACATCCATTGCGTTTTGCGACATCAGAG
ACATGTTTGCATGGGGGATTTGAGGTTCTTCATGATAAGGGACCACTTGATACTCTAAATCAGAAAATTGGATCCTCTGT
ATTTCGTGTTGAACAGCAGCCAGATGGTACCCATGCTGCTATTGGGGTAAAAGATGGTGTAGAGGTTAGCGTTACATTAA
ATTCTAGTGAATTGCAAAGCTTGCAATCTCTTGACACTGAAGGTAACGGTCGATTTGTTTTCACCGGGGGACGTGGTGGT
AGTGGGCATGCCATGGTCACTGTTGCATCAGATATCTCGCAAGCTCGTGAGAAAATAATAGCTAAGTTAGATCCAGACAA
CCATGGAGGAAGACAACCTAAGGACATTGATACACGTTCTGTTGGTGTCGGAAGTGCTTCAGGAATGGGAGATGGAGTTG
TTAGCGAAACTCATACTTCAACAACAACTTCAAGTGTTCGTTCAGATCCTAAATTCTGGGTTTCTGTTGGCGCAATTGCT
GCTGGTTTAGCGGGGCTGGCAGCTACAGGTATTGTTCAGGCGGTTGCTTTGACACCAGCTCCGGATGATCCTACAACCAC
AGATCCTGATGAAGCCGCAAATGCTGCAGAAGCTGCGACAAAAGATCAGTTAACGAAGGAGGCGTTCCAGAATCCTGATA
ATCAGAAAGTTAACATTGATGAGCTCGGAAATGCAATTCCGTCGGGTGAGTTAAAAGATGATGTTGTTGCGCAAATAGCA
GATCAGGCTAAAGTGGCGGGTGAACAGGCCAGACAGCAAGCTGTTGAAAGCAATGCACAGGCGCAGCAGCGGCATGATGA
TCAGCAGGCTAAACGTCAGCAGGAATTGGATCTCTCATCAGGTATTGGTTACGGCCTCAGTAGTGCATTGATTGTTGGTG
GGGGGATTGGTGCTGGTGTTACGGCTATGCTCCATAGACGAAATCCGCCGACAGAACAGACAATAGCTACTACACATTCG
GTTATTCAGCAGCAGACCGGGGGAAATACTCGAGCACAAGGCGGCGCTGACACCACTGGAGTGGAAAACGCTTCTCTGAC
TAGACGTGATTCGCAGGCTAGTGTTGCATCGACCCAATGGTCAGATACCTCTGGCGATGTGGTGAATCCGTATGCTGAAG
GTTGGATGTCCAGGAATAATCCATCGCTTCTCGCTCCAGAAGAGCCTATTTATGATGAAGTCGCTCCGGATCCTAACTAT
AGCGTTATTCAGCATTTTTCAGGGAATAATCCTGTGACTGGGCGGTTAGTAGGATCTCCTGGGCAGGGTATCCAAAGCAC
TTATGCGCTTCTCGCAAGCAGCGGTGGATTGCGATTAGGTATGGGAGGATTGACTGGGGGAGGTGAGAGCGCAGGGAGCG
CTGCGAATGCCGCTACAACACCGGGAGTTGAACGTTTCGTCTAA

Protein sequence :
MPIGNLGNNNISNNLIPPAPPLPSQTDGATRGNGSSLISSTGSLGSRLLFSPLRSSIVDTVDSRDVPGLPEHPLRFATSE
TCLHGGFEVLHDKGPLDTLNQKIGSSVFRVEQQPDGTHAAIGVKDGVEVSVTLNSSELQSLQSLDTEGNGRFVFTGGRGG
SGHAMVTVASDISQAREKIIAKLDPDNHGGRQPKDIDTRSVGVGSASGMGDGVVSETHTSTTTSSVRSDPKFWVSVGAIA
AGLAGLAATGIVQAVALTPAPDDPTTTDPDEAANAAEAATKDQLTKEAFQNPDNQKVNIDELGNAIPSGELKDDVVAQIA
DQAKVAGEQARQQAVESNAQAQQRHDDQQAKRQQELDLSSGIGYGLSSALIVGGGIGAGVTAMLHRRNPPTEQTIATTHS
VIQQQTGGNTRAQGGADTTGVENASLTRRDSQASVASTQWSDTSGDVVNPYAEGWMSRNNPSLLAPEEPIYDEVAPDPNY
SVIQHFSGNNPVTGRLVGSPGQGIQSTYALLASSGGLRLGMGGLTGGGESAGSAANAATTPGVERFV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAL06376.1 translocated intimin receptor Tir Virulence LEE Protein 4e-158 100
tir AAC38390.1 Tir Virulence LEE Protein 6e-112 79
tir YP_003236081.1 putative translocated intimin receptor Tir Not tested LEE Protein 6e-104 76
tir AAY25394.1 translocated intimin receptor Virulence LEE Protein 1e-103 76
tir AAY25393.1 translocated intimin receptor Virulence LEE Protein 3e-104 76
tir AAY25395.1 translocated intimin receptor Virulence LEE Protein 3e-104 76
espE CAC81869.1 EspE protein Virulence LEE II Protein 3e-98 68
tir YP_003232160.1 translocated intimin receptor Tir Virulence LEE Protein 4e-98 68
tir AAK26722.1 Tir Virulence LEE Protein 2e-98 68
tir AAL57549.1 Tir Virulence LEE Protein 2e-98 68
tir CAI43867.1 translocated intimin receptor Not tested LEE Protein 5e-96 67
tir YP_003223468.1 translocated intimin receptor Tir Virulence LEE Protein 7e-96 67
tir ACU09451.1 translocated intimin receptor protein Tir Virulence LEE Protein 2e-70 57
ECs4561 NP_312588.1 hypothetical protein Virulence LEE Protein 3e-70 57
tir AAY25390.1 translocated intimin receptor Virulence LEE Protein 3e-70 57
tir AAY25391.1 translocated intimin receptor Virulence LEE Protein 3e-70 57
tir AAC31506.1 L0027 Virulence LEE Protein 2e-70 57
tir AAY25392.1 translocated intimin receptor Virulence LEE Protein 2e-70 57
tir NP_290261.1 translocated intimin receptor protein Not tested LEE Protein 3e-70 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tir YP_003366495.1 Tir, translocated intimin receptor VFG0737 Protein 3e-112 79
tir YP_003366495.1 Tir, translocated intimin receptor VFG0805 Protein 1e-70 57