Gene Information

Name : eae (ROD_29831)
Accession : YP_003366493.1
Strain : Citrobacter rodentium ICC168
Genome accession: NC_013716
Putative virulence/resistance : Virulence
Product : intimin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3155697 - 3158507 bp
Length : 2811 bp
Strand : -
Note : -

DNA sequence :
ATGATTATTCATGGTTTTTGCACCGGGACCCGGCACAAGCATAAGTTAAGAAAAACATTTATTATGCTTGGTGCTGGTTT
AGGATTGTTTTTTTCTGTTAACCAGAACTCATTTGCAAATGGTGAAAATTACTTTAAGTTAAGAGCCGATTCTAAACTAA
TAAATAATAATATTGCTCAGGATCGTCTTTTTTATACCTTGAAAACGGGTGAAAGCGTTGCTCAGCTTTCTAAATCACAA
GGGATCAGCGTGCCGGTTATTTGGTCGCTGAATAAGCATTTATATAGCTCTGAAAGTGAAATGATGAAGGCTAGTCCTGG
TCAGCAGATCATTTTACCGCTCAAAAAACTTTCTGCTGAATATAGTACCTTGCCTATTTTAGGTACAGCACCTGTCGTTG
CTGCAGCTGATGTTGCTGGTCACACGAAAAAAATGTCCCAGGATACGACCAAAAGCAATACAAGCGATGACAAGGCCTTA
AACTATGCAGCACAACAGGCCGCGAGCCTCGGTAGCCAACTTCAGTCTCGCTCACTGAACGGAGACTATGCGAAAGATAC
AGCCCTTAGTATGGCTGGTAACCAAGCCTCATCCCAGATGCAGGCTTGGTTACAGCATTATGGAACGGCAGAGGTTAATC
TGCAGAGCGGTAATAACTTTGATGGCAGTTCACTGGACTTCTTATTACCGTTCTATGATACTGAAAATATGCTGGCATTT
GGTCAGGTTGGAGCGCGTTATATTGACTCTCGCTTTACGGCAAACTTAGGGGCTGGTCAGCGTTTTTTCCTTCCTGAAAA
TATGTTGGGCTATAACGTCTTCATTGATCAGGATTTTTCTGGTAACAATACCCGCTTAGGAATCGGCGGTGAATATTGGC
GAGACTATTTTAAAAGTAGCGTTAACGGCTATTTCCGCATGAGCGGTTGGCATGAGTCATACAATAAGAAAGACTATGAT
GAGCGCCCGGCAAATGGTTTCGATATTCGCTTTAACGGCTACTTACCATCATATCCTGCATTAGGTGGCAAGCTGATGTA
TGAGCAGTATTATGGTGATAATGTTGCTTTGTTTAATGCCGATAAGCTGTATTCGAATCCTGGTGCGGTGACAGTTGGTG
TCAACTACACTCCGATTCCTTTGGTGACGATGGGGATTGATTATCGTCATGGTACAGGTAATGAAAATGATCTCCTGTAC
TCAATGCAGTTCCATTATCAATTTGATAAACCATGGTCTCAACAAATTGAGCCACAGTATGTTAACGAGTTAAGAACATT
ATCAGGCAGCCGTTACGATCTGGTACAGCGTAATAACAACATTATTCTGGATTACAAAAAGCAGGATATTCTTTCTATGA
ATATTCCGCATAATATTAATGGTACTGAACACAGTACGCATAAGATCCAATTGATCGTTAAGAGTAAGTACGGTCTTGAG
CGTATCGTATGGGATGACAGTACATTACGCACTCAGGGTGGTCAGATTCAGCATAGCGGAAGCCAAAGCGCACAAGATTA
TCAGGCTATTTTGCCTGCTTATGTGCAAGGCGGTAGCAATGTTTATAAAGTGACCGCTCGCGCCTATGACCGTAATGGAA
ATAGCTCTAACAATGTACAGCTTACTATTACCGTTCTGTCGAATGGTCAAGTAGTCGACAAGGTTGGGATAACGAACTTT
ACGGCGGATAAGACATCGGCTAAAGCGGATAATGCGGATACCATTACTTATACCGCGACTGTGAAAAAGAATGGGGTAGC
TCAGGCTAATGTCCCTGTTTCATTTAATATTGTTTCAGGAACTGCAACTTTAAGTGCCAAGAGTGCCAATACTAATAGTA
GCGGTAAGGCGACTGTAACGCTGAAATCAGACAAGCCGGGCCAGGTAGTTGTGTCAGCTAAAACAGCGGAGATGACTTCA
GCACTTAATGCCAATGCGGTTATATTTGTTGATCAAACCAAAGCCAGCATTACTGAGATTAAGGTTGATAAGACAATAGC
GACGGCAGACAATAAGGATACTATTGAATACACAGTTAAAGTGATGAAGGGTGGGAATCCTATTTCTGGTCAAAAAGTGA
CCTTCTCTAAGGATTTTGGGACCCTAAATAAGACTGAAGCAACAACCGATCAGAATGGTTATGCTACTGTAAAATTGTCA
TCCGGAACTCCGGGTAAGGCTATAGTTAGCGCAAAAGTGAGTGAGGTAAATACAGAAGTTAAGGCCGCCACTGTTGAATT
TTTTGCCCCACTGAGTATCGATGGCAATAAAGTGACTGTAATTGGTACTGGTGTCACTGGTTCTTTGCCAAAGAACTGGT
TACAGTATGGTCAGGTTAAGCTACAGGCAACAGGAGGCAACGGGAAATATACATGGAAATCCAGTAATACTAAAATTGCT
TCTGTTGATAATTCGGGAGTGATAACTTTAAATGAGAAAGGCAGTGCTACAATTACTGTAGTATCGGGTGATAATCAGAG
TGCGACATATACAATTAATACACCAGACAATATTATAATAGCGGTGGATAAAATTAATCGGATGGCGTATTCTGAGGCAG
AAAGCAGGTGTCAAGCAATTAGTTCAAATTTAGCACAGTCAAAAAGCGTATTGGAAAATATATATTCTAAATGGGGAGCC
GCGAATAAATATCCTTATTATTCGAGTTCTAATTCATTGACAGCTTGGATTAAGCAATCTACTTCTGATTCTGCATCAGG
TGTATCAAATACATATGATTTAGTTACAACAAACTCTTTGACAAATGTTAAAGCAACAGATAAAAATGCTTTTGCAGTTT
GTGTAAAATAG

Protein sequence :
MIIHGFCTGTRHKHKLRKTFIMLGAGLGLFFSVNQNSFANGENYFKLRADSKLINNNIAQDRLFYTLKTGESVAQLSKSQ
GISVPVIWSLNKHLYSSESEMMKASPGQQIILPLKKLSAEYSTLPILGTAPVVAAADVAGHTKKMSQDTTKSNTSDDKAL
NYAAQQAASLGSQLQSRSLNGDYAKDTALSMAGNQASSQMQAWLQHYGTAEVNLQSGNNFDGSSLDFLLPFYDTENMLAF
GQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGNNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKKDYD
ERPANGFDIRFNGYLPSYPALGGKLMYEQYYGDNVALFNADKLYSNPGAVTVGVNYTPIPLVTMGIDYRHGTGNENDLLY
SMQFHYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILDYKKQDILSMNIPHNINGTEHSTHKIQLIVKSKYGLE
RIVWDDSTLRTQGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSSNNVQLTITVLSNGQVVDKVGITNF
TADKTSAKADNADTITYTATVKKNGVAQANVPVSFNIVSGTATLSAKSANTNSSGKATVTLKSDKPGQVVVSAKTAEMTS
ALNANAVIFVDQTKASITEIKVDKTIATADNKDTIEYTVKVMKGGNPISGQKVTFSKDFGTLNKTEATTDQNGYATVKLS
SGTPGKAIVSAKVSEVNTEVKAATVEFFAPLSIDGNKVTVIGTGVTGSLPKNWLQYGQVKLQATGGNGKYTWKSSNTKIA
SVDNSGVITLNEKGSATITVVSGDNQSATYTINTPDNIIIAVDKINRMAYSEAESRCQAISSNLAQSKSVLENIYSKWGA
ANKYPYYSSSNSLTAWIKQSTSDSASGVSNTYDLVTTNSLTNVKATDKNAFAVCVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAL06378.1 intimin Virulence LEE Protein 0.0 100
eae AAL57551.1 Eae Virulence LEE Protein 0.0 87
eae CAC81871.1 Intimin Not tested LEE II Protein 0.0 87
eae AAK26724.1 intimin Virulence LEE Protein 0.0 87
eae YP_003232162.1 intimin Not tested LEE Protein 0.0 87
eae AAC38392.1 intimin Virulence LEE Protein 0.0 79
eaeA AAC31504.1 L0025 Virulence LEE Protein 0.0 78
unnamed ACU09449.1 gamma intimin Virulence LEE Protein 0.0 78
eae NP_290259.1 intimin adherence protein Virulence LEE Protein 0.0 78
ECs4559 NP_312586.1 gamma intimin Virulence LEE Protein 0.0 78
eae CAI43865.1 intimin epsilon Virulence LEE Protein 0.0 78
eae YP_003223466.1 intimin epsilon Not tested LEE Protein 0.0 78
eae YP_003236079.1 theta intimin Not tested LEE Protein 0.0 77
eae AFO66392.1 intimin-like protein Virulence SESS LEE Protein 0.0 60
eae AFO66294.1 intimin-like protein Not tested SESS LEE Protein 0.0 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
eae YP_003366493.1 intimin VFG0739 Protein 0.0 79
eae YP_003366493.1 intimin VFG0803 Protein 0.0 78