Gene Information

Name : lpfC (ROD_18161)
Accession : YP_003365379.1
Strain : Citrobacter rodentium ICC168
Genome accession: NC_013716
Putative virulence/resistance : Virulence
Product : fimbrial usher protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 1933519 - 1935966 bp
Length : 2448 bp
Strand : -
Note : -

DNA sequence :
ATGATTACCAGCCTGCTGAATGAGGCGAGAGGGCGTGACTATTTTAATCCGGCGCTGCTGGAGAATAACCCAACCGCTGC
GGATAATATCGATCTCTCTGCTTTTGAAACGGGACAACAGGCGCAGGGAACTTATCGCGTCGATATTATTCTCAACGGGG
CGAATGTGGATACGCGTGAGATAGCCTTTTTCCCGGGGGAAGAGGGGGATCTTGAGCCGTGTCTCTCTGAAGCGCTGTTA
CAGCGTTATGGCGTAAAAACCGCGTCCTACCCTGGGCTTATGGCGAAGGGAAAGTGCGCGGACCTGGCCGCCATTCCTCA
GGCCTCCAGCGAGCTGTTATTTAGCGCGCAGAAACTGCTGCTCACTATTCCGCAGGCCGCCTTATCCGCGCAGGCGCGCG
GCTATGTCGCCCCCGAATTGTGGGATGAGGGGATTAGCGCCGTGATGCTTAATTACAGCTTCAGTGGGGATCGTAGCCGG
ACAAACGCGGATGGCGTAACAAGTAACAGTCAGTACGCCAGCCTGCGTCCTGGGATCAATGTCGGCCCGTGGCGGTTGCG
AAACTATACGACCTGGAACCGCGACAGTCAGGGAAATGACAACTGGGATACGGTTTATACCTATCTTCAGCGCAATATTG
TGCCGCTTAAAGCGCAGCTGGTGCTGGGCGACAGCGCCTCGCCCGCAGATATCTTTGACAGCATTCCGTTTCGCGGCGCG
CAGCTTGCCTCTGATGACGAAATGCTGCCGGATTCGCTGAAAGGCTACGCACCGGTGGTGCGGGGGATCGCGCGAAGCCA
TGCGCAGGTGATCATTCGGCAAAACGGCTATCAGATTTATCAGAGCTACGTGGCGCCAGGAGCATTCGAAATCAGCGATC
TGTACCCGACCGGCGGCGCAGGCGATTTAGATGTCACCCTGAAAGAAGCCGACGGCGGCGAACAGCACTTTACGGTGCCG
TTTGCATCCTTACCGGTGCTCCAGCGTGAAGGGCGCGTCAAATATGCCTTAACTGCCGGACGCTACCGTTCCTACGACAG
CCGGGTGGCGCAGAGCGGGTTTGCGCAGGGAACGACGATTTACGGGCTGCCGGCGGCCGTTACCGTGTACGGCGGGCTTC
AGGCGGCCGATGACTATCGCGCAGTGGCGGCTGGCGCAGGCAAGAATTTTGGCGTCGTCGGGGCGCTCTCTACCGACCTG
ACCCGCTCCTGGTCGCAGCCGCGAAACGCGGCGAAGGCGCAGGGGCAATCCTGGCGTATTCGTTACAGTAAGAACAGCGT
ACTGACCGGAACGCATTTTGCCATTGCCGGGTATCGCTACTCGACCCGTGACTTTTACGCGATGGAAGAAGTGTTTACTA
CCCGGGGCGGCAGTAATACGCCTGCGCAGAAGCGACGTAACCGGATGGAGGCGAACGTCAGCCAGTCTCTCGGCCAGGGG
CGCGGCGCGCTTTCGCTCAGCGCTGTACGGGAAGAGTACTGGAACAGAGAAAACCCCATGCAATCGTGGAGTGTCAGCTA
TAACAATGCCTGGAACGGGGTAAGTTACGGTATTAGCTGGACGCAGAGTAAAAATAGCCTTTCCGGTACAGACAACCGTT
ACGAAAAAGATCAGCAGATAGCCTTTAACGTCAGCGTTCCGCTGGAGGGCTTCATGGCAAACAGTTGGGCGCACTACAGT
CTTAACGGCGGTCGCAATGCCGGGACAACGCACAGCGCAGGTCTGAGCGGTATGGCCCTGGCGGATAATGCGCTTAACTG
GAACCTGCAACAGGGATACGGCAGCGACGGCGTGGGCTATACCGGCAGTCTCAACGCTGACTATAAAGGAACCTATGCCC
AGGTCAGCAGCGGCTATAGCTACGACAGCAATATGCAACGGCTGAACTATGCGCTGGCGGGCGCGCTGCTGGCGCATGCT
GACGGCGTCACGCTCTCCCAGCCGCTGGGGGAAACCAATGTTCTGATTAAAGCGCCGGGTGCGAACGGCGTTGGGGTGAA
AAATCAGCGCGGCGTCAAAACTGATTTTCGCGGTTACACGGTTGCCGGCAACGTTTCGCCGTACCGTAACAATGATATCG
GACTGGATACGTTATCCGTTCCGGCCAACGTTGAACTGGAATTGACCAATAAAAACGTAGTGCCGACCCGCGGGGCGGTG
GTACGCGCAGAGTTTGTCGCCAGCGTGGGATTGCGCCTGTTGCTGACTTTGCATCGCGACAACGGGCGTCCCGTGCCGTT
CGGCGCCAGGGTCGTCGTTCAAGGCGCTCAGGGACCCGGCTTTATTGTTGGCGATGACGGTCAGGTTTATCTGAGCGGTA
TGCAGCCGCAGGGCGAACTTGATGTCGCCTGGGGGGATGACCCGCAGCAGCGCTGCACCGTGGAATATTCGTTTAAAGCG
GCGGTCGGAAGTGGCGATATTATCACTGACGCTCGTCTTTGCCGCTAA

Protein sequence :
MITSLLNEARGRDYFNPALLENNPTAADNIDLSAFETGQQAQGTYRVDIILNGANVDTREIAFFPGEEGDLEPCLSEALL
QRYGVKTASYPGLMAKGKCADLAAIPQASSELLFSAQKLLLTIPQAALSAQARGYVAPELWDEGISAVMLNYSFSGDRSR
TNADGVTSNSQYASLRPGINVGPWRLRNYTTWNRDSQGNDNWDTVYTYLQRNIVPLKAQLVLGDSASPADIFDSIPFRGA
QLASDDEMLPDSLKGYAPVVRGIARSHAQVIIRQNGYQIYQSYVAPGAFEISDLYPTGGAGDLDVTLKEADGGEQHFTVP
FASLPVLQREGRVKYALTAGRYRSYDSRVAQSGFAQGTTIYGLPAAVTVYGGLQAADDYRAVAAGAGKNFGVVGALSTDL
TRSWSQPRNAAKAQGQSWRIRYSKNSVLTGTHFAIAGYRYSTRDFYAMEEVFTTRGGSNTPAQKRRNRMEANVSQSLGQG
RGALSLSAVREEYWNRENPMQSWSVSYNNAWNGVSYGISWTQSKNSLSGTDNRYEKDQQIAFNVSVPLEGFMANSWAHYS
LNGGRNAGTTHSAGLSGMALADNALNWNLQQGYGSDGVGYTGSLNADYKGTYAQVSSGYSYDSNMQRLNYALAGALLAHA
DGVTLSQPLGETNVLIKAPGANGVGVKNQRGVKTDFRGYTVAGNVSPYRNNDIGLDTLSVPANVELELTNKNVVPTRGAV
VRAEFVASVGLRLLLTLHRDNGRPVPFGARVVVQGAQGPGFIVGDDGQVYLSGMQPQGELDVAWGDDPQQRCTVEYSFKA
AVGSGDIITDARLCR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 2e-136 42
sfaF CAC16953.2 SfaF protein Virulence PAI III 536 Protein 4e-141 42
lpfC YP_006098365.1 fimbrial outer membrane usher protein Not tested Tn2411 Protein 2e-133 41
lpfC NP_839216.1 long polar fimbriae Not tested SHI-2 Protein 2e-135 41
lpfC NP_709462.1 long polar fimbriae Not tested SHI-2 Protein 2e-135 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lpfC YP_003365379.1 fimbrial usher protein VFG0446 Protein 2e-141 44
lpfC YP_003365379.1 fimbrial usher protein VFG0454 Protein 3e-157 43
lpfC YP_003365379.1 fimbrial usher protein VFG0876 Protein 2e-144 43
lpfC YP_003365379.1 fimbrial usher protein VFG1645 Protein 3e-141 42
lpfC YP_003365379.1 fimbrial usher protein VFG0912 Protein 1e-140 42
lpfC YP_003365379.1 fimbrial usher protein VFG0944 Protein 2e-136 41