Gene Information

Name : topB (ROD_12951)
Accession : YP_003364880.1
Strain : Citrobacter rodentium ICC168
Genome accession: NC_013716
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1391761 - 1393707 bp
Length : 1947 bp
Strand : +
Note : -

DNA sequence :
ATGCGGTTGTTTATTGCCGAAAAGCCGAGTCTGGCCCGCGCGATTGCCGATGTGCTGCCGAAGCCGCACCGTAAAGGCGA
TGGCTTCATCGAGTGCGGAAACGGGCAGGTGGTCACCTGGTGTATCGGCCACCTGCTGGAGCAGGCGCAGCCTGACGTCT
ATGACAGCCGCTATGCGCGCTGGAATCTTTCCGACCTGCCGATTGTGCCGGAAAAGTGGCAGTTGCAGCCGCGTCCGTCG
GTGACCAAACAGCTTAATGTGATCAAGCGGTTCCTGCATGAAGCCAGTGAAGTCGTTCACGCCGGCGACCCGGATCGTGA
AGGGCAGCTGCTGGTCGATGAAGTGCTGGATTACCTGCAGCTGGCGGCGGAAAAGCGTCAGCAGGTGCAGCGCTGCCTGA
TCAACGACCTGAACCCGCAGGCGGTAGAGCGGGCCATTGAGCGTCTGCGTTCCAACAGCGAGTTTGTGCCGCTGTGCGTT
TCGGCGCTGGCGCGCGCCCGCGCCGACTGGCTGTACGGCATCAATATGACCCGCGCTTATACCATTCTCGGACGCAATGC
TGGTTATCAGGGCGTGCTCTCGGTCGGGCGCGTCCAGACGCCGGTGCTGGGGCTGGTGGTGCGTCGCGACGAAGAAATTG
AGAACTTTATTCCAAAAGATTTCTTTGAGGTGAGAGCGCATATCGTCACTCCCGCTGACGAGCGTTTTATCGCTATATGG
CAGCCGAGCGAAGCCTGTGAGCCGTATCAGGACGAGGAGGGGCGACTGCTGCACCGTCCGCTGGCCGAGCATGTGGTGAA
CCGGATCAACGGTCAACCGGCCTTCGTCACCAGCTATAACGATAAACGGGAATCAGAATCCGCGCCGCTGCCGTTTTCGC
TTTCCGCCCTGCAGATTGAGGCGGCAAAGCGTTTCGGCCTGAGCGCGCAAAACGTTCTCGACATCTGCCAGAGGCTGTAT
GAAACCCATAAACTGATCACCTACCCGCGTTCTGACTGCCGCTACCTGCCGGAAGAGCACTTTGCCGGTCGTCATGCGGT
GATGAACGCTATCGGCGTTCACGCGCCGGATCTTCTGCCGCAGCCGGTGGTTAACCCGGATACCCGCAACCGCTGCTGGG
ATGATAAAAAGGTCGATGCGCACCACGCCATCATTCCTACTGCGCGCAGTTCGACAATCAACCTCAGCGAAAATGAAGCG
AAGGTTTATAACCTGATTGCGCGTCAGTATCTGATGCAGTTCTGTCCGGATGCGGTGTTCCGCAAATGTGTGATAGAGCT
GGAGATCGCCAAAGGCAAATTTATCGCCAAAGCGCGCTTCCTGGCGGAAGCCGGGTGGCGCACGCTGCTGGGCAGTAAAG
AGCGCGACGAGGAGAACGACGGAACGCCGCTGCCGGTGGTGGCGAAAGGTGATGAGCTGCTGTGTGAAAAGGGCGAGGTC
GTTGAGCGTCAGACCCAGCCACCGCGGCACTTTACCGACGCCACGCTGCTGTCGGCGATGACGGGGATCGCCCGCTTTGT
GCAGGATAAAGATCTGAAGAAGATCCTGCGCGCCACCGACGGGCTGGGAACGGAAGCGACCCGCGCCGGGATTATCGAGC
TGTTGTTTAAGCGCGGTTTTTTAACCAAAAAAGGGCGCTATATTCACTCGACCGACGCTGGCAAAGCGCTGTTCCACTCG
CTGCCGGAGATGGCGACCCGTCCCGATATGACCGCGCACTGGGAGTCGGTGCTGACGCAAATCAGCGAAAAGCAGTGCCG
CTATCAGGATTTTATGCAGCCGCTGGTAGGAACGCTGTATCAGCTGATCGATCAGGCGAAGTCGACGCCGGTTCGCCGCT
TTCGCGGCATTGTCGCCCCCGGCGGCGGAAGCAGCGAGAAGAAAAAGAGCGCGCCGCGTAAGCGGGCGGCGAAAAAAAGC
CCGCCATCGGCAGAGGCGGGCCTGTAG

Protein sequence :
MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDVYDSRYARWNLSDLPIVPEKWQLQPRPS
VTKQLNVIKRFLHEASEVVHAGDPDREGQLLVDEVLDYLQLAAEKRQQVQRCLINDLNPQAVERAIERLRSNSEFVPLCV
SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFIPKDFFEVRAHIVTPADERFIAIW
QPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPAFVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQRLY
ETHKLITYPRSDCRYLPEEHFAGRHAVMNAIGVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSTINLSENEA
KVYNLIARQYLMQFCPDAVFRKCVIELEIAKGKFIAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHS
LPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKSTPVRRFRGIVAPGGGSSEKKKSAPRKRAAKKS
PPSAEAGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 3e-107 41
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 2e-107 41
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 3e-107 41
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 4e-104 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-111 41