Gene Information

Name : RMDY18_08360 (RMDY18_08360)
Accession : YP_003362488.1
Strain : Rothia mucilaginosa DY-18
Genome accession: NC_013715
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 909851 - 911314 bp
Length : 1464 bp
Strand : +
Note : -

DNA sequence :
ATGAGGCGCGCAAAAATCGTTGCAACCATCGGTCCGGCAATCGAGTCCCCCGAGAAGATCTCCGAGGCAATCAAGGCTGG
CCTGAACGTCGCCCGTCTGAACATGAGCCACGGTGACCACGCCGAGCACCAGGCACGCTACGACACCATCCGTGAACAGT
CTGCAAAGCTTGGTAAGGACGTTGCAATCCTCGCCGACCTGCAGGGCCCCAAGATTCGCCTCGAGCGTTTCGCAAACGGC
AAGGAATACCTTGAGCCCGGCGCAGACTTCACCATCACCTCCGAAGACGTTGAAGGTACCGCAGAAATCTGTGGCACCAC
CTACAAGGGCCTGCCCGGCGACGTAAAGCCCGGCGACAAGCTCCTGCTCGACGATGGCAAGATCCGCCTCGAAGCTATTG
AGGTAACTCCCACCCGCGTTCGCACCCGCGTGGTCGTCGGTGGTCCCATCTCCAACAACAAGGGCATCAACCTGCCCGGC
GCAGCAGTCTCCCTGCCCGCGCTGACCGAGAAGGACGCAAACGACCTGCGCTTCGCACTGAAGATGGGTGCAGACATTAT
TGCGCTCTCCTTCGTTCGTACCGGTGCAGACGTTGACCCCGTCCACAAGATCATGGACGAAGAGGGTATCCGCGTACCCG
TCATCGCCAAGATCGAGAAGCCCCAGGCAGTTGAGAACCTGCAGGACATCATCGACAAGTTCGACGGCATCATGGTCGCT
CGTGGTGACCTCGGTGTTGAGCTGCCCTTCTCCGAGGTTCCCCTCGTCCAGAAGAAGGCAATCGACATGGCACGCCGCTG
GGCAAAGCCCGTCATCGTGGCAACCCAGGTGCTCGAGTCCATGACCGACAACCCCGTCCCCACCCGTGCAGAGGTTTCTG
ACTGCGCTAACGCAATCCTCGACGGTGCAGACGCTGTGATGCTCTCCGGTGAGACCTCGGTCGGTAAGTACCCGATCCTG
ACCCTGCAGGCTATGGCTGCAATCGTTCAGGATACCGAAAAGGGTGGCCTGTACCGCGTGCCCGAGCTGGACCGCAAGCC
CCGCACCCGCGGTGGCGCAATCACCCGCGCAGCAGTGAACATCGCTGACCAGCTGGACGCAAAGCTCATCGTAACCTTCA
CCCAGTCCGGTGACTCCGCACGTCGTCTGGCACGTCTGCGTCCCGAGACCCCGATTGTCGCGTTCACCACCAGCTCGAAG
GTTCGCTCCTTCCTGTCCATGTTGTGGGGCGTTGAGGCTGAGCAGGTTGAGATGATCACCGATCAGGAAGGTCTGTTCCA
CTTCGTGGACGAGTACCTGCTGAAGAACGGTCTGGCAGAAGCTGGCGACCTGGTCGTCGTTGCTGCCGGTGCTCCCGCAG
GCCGCGCAGGTACCACCAACATGGTTCAGGTACACCGCGTCTACGGTGCTGAGGGCGAGCGCGAGGCTCTGCGTCCTTAC
GAGGAGAACGAGGTCAAGCGCTAA

Protein sequence :
MRRAKIVATIGPAIESPEKISEAIKAGLNVARLNMSHGDHAEHQARYDTIREQSAKLGKDVAILADLQGPKIRLERFANG
KEYLEPGADFTITSEDVEGTAEICGTTYKGLPGDVKPGDKLLLDDGKIRLEAIEVTPTRVRTRVVVGGPISNNKGINLPG
AAVSLPALTEKDANDLRFALKMGADIIALSFVRTGADVDPVHKIMDEEGIRVPVIAKIEKPQAVENLQDIIDKFDGIMVA
RGDLGVELPFSEVPLVQKKAIDMARRWAKPVIVATQVLESMTDNPVPTRAEVSDCANAILDGADAVMLSGETSVGKYPIL
TLQAMAAIVQDTEKGGLYRVPELDRKPRTRGGAITRAAVNIADQLDAKLIVTFTQSGDSARRLARLRPETPIVAFTTSSK
VRSFLSMLWGVEAEQVEMITDQEGLFHFVDEYLLKNGLAEAGDLVVVAAGAPAGRAGTTNMVQVHRVYGAEGEREALRPY
EENEVKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-68 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-68 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-68 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-68 42
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 3e-55 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RMDY18_08360 YP_003362488.1 pyruvate kinase VFG0479 Protein 1e-68 43