Gene Information

Name : clpC (BDP_0780)
Accession : YP_003360265.1
Strain : Bifidobacterium dentium Bd1
Genome accession: NC_013714
Putative virulence/resistance : Virulence
Product : Negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 894254 - 896845 bp
Length : 2592 bp
Strand : +
Note : -

DNA sequence :
ATGTTCGAACGGTTTACAGACCGTGCCCGGCGCGTGATCGTGCTGGCTCAGGAAGAAGCTCGTACCCTCCAGCACAACTA
CATCGGTACCGAGCATCTGCTGCTCGGCCTGATTCGTGAGGGTGAGGGCGTCGCCGCGAAGGCGCTGGCCTCGAAGGGTG
TGTCGTTGGACGATACCCGCAAGCAGGTCGAAGAGATGATCGGTAAGGGGAATGCGTCGCCGAACGGCCACATTCCTTTT
ACTCCGCATGCCAGGCAGGTGTTGGAGCTGTCGTTGCGTGAAGCGTTGCAGCTGGGGCACAGCTATATCGGTACCGAGCA
CATTCTGCTCGGCCTGATTCATGAGGGCGAAGGCGTCGGTACCCAGGTGCTGATCAAGATGGATGTCAATCTCGGCGAGC
TGCGCAGTGCGACCATCGATCTGATCCGTGGCAATTCAGGCGGTAGCCAGGGTGAAGGCAAGGGCGATCTCGCCAATGCC
GGCGGCGTGCAGGATAGGCGGAACCAGAGCGGTTCGGCCATTCTCGACCAGTTCGGTCGCAATCTGACCGCCGAAGCCGC
TTCGGGTAAGCTCGACCCGGTGATCGGTCGTTCGAGCGAGATCGAACGCGTAATGGTGGTGCTGAGCCGGCGTACCAAGA
ACAATCCGGTGCTGATCGGTGAGCCGGGCGTCGGCAAGACCGCCGTGGTCGAGGGTTTGGCCCAGAAGATCAACGCCGGC
GATGTGCCGGAGACGTTGAAAGGCAAGCAGGTCTATTCCCTGGACTTGGGTTCCATGGTGGCAGGTTCACGCTATCGTGG
CGATTTCGAGGAACGCCTGAAGAAGGTCTTGAAAGAGATCAAGACCCGTGGTGACATCGTGCTGTTCATCGACGAGATCC
ATACCATCGTGGGCGCAGGTTCCGCGGACGGTGCCTTGGGCGCTTCCGACATGCTTAAGCCCATGCTGGCTCGCGGCGAA
CTGCAGACCATCGGCGCCACCACCACCGACGAGTACCGCAAGTACATCGAAAAGGATGCGGCGCTGGAACGCCGTTTCCA
GCCGATTCAGGTGCATGAGCCGACCATCGCCGAAACCATCGAGATCCTGAAGGGTCTGCGTGAACGCTACGAGAATCACC
ATCATGTGACGATTACCGATGGTGCGCTGCAATCCGCAGCAGAGTTGTCTTCGCGTTACATTCAGGACAGTCATCTGCCC
GATAAGGCCATCGATCTGATCGATGAGGCCGGTGCGCGCCTGCGTATCCGCCGTCTGACCGCCCCGCCGGAGCTCAAGGA
GCTTGATGCGAAGGTGGCCAAGCTGGCCGAAGAGAAGGATCAGGCCATCAAGGACCAGGACTTCGAGAAGGCGGCCGAGC
TGCGCGACAGGCAGGAGAAGCTGGAAGCTGAGCGCAAGGAGAAGGAATCGTCCTGGCGTGAAGGCGAATCCGACGTGAAG
ATGGTCGTGGACGAGGATGTGATTGCCGAAGTGATCTCGCAGACCACCGGCATTCCGGTGTTCAAGCTCACTCAGGCTGA
ATCCAAGAAGCTCATGAGCATGGAATCCGAGCTGCACAAGCGCATCATCGGTCAGGACGAGGCCGTGTCGGCGCTGTCCC
GCTCCATCCGCCGTGCGCGTGTGGGCCTGAAGGACCCGAAGCGCCCGTCCGGTTCATTCATCTTCGCCGGCCCGACTGGT
GTGGGCAAGACCGAGCTGGCCAAGACGCTGGCGGAGTTCCTGTTCGATGATGAGGACGCGTTGATCCGCGTGGATATGTC
GGAGTTCTCCGAAAAGTACGCCGCATCGCGTCTGTTCGGCGCCCCTCCGGGATATGTCGGCTATGAGGAGGGCGGCGAGC
TCACCGAAAAGGTGCGTCGCAAGCCGTTCTCCGTGGTGCTGTTCGACGAGATCGAGAAGGCGCATCCGGACATCTTCAAC
ACATTGTTGCAGGTGCTCGATGATGGTCATCTGACCGATGGCCAGGGCCGCAAGGTAGATTTCAAGAACACCATCATCAT
CCTGACCACCAATCTCGGCACCCGCGACATCGCGAAGGCCGCCAACACGGGCTTCAATCTTGGTACGAACACCGAGTCGA
GCTACCAGCGCATGAAGGATCAGGTCTCTTCGGAATTGAAGCAGCAGTTCCGTCCGGAGTTCCTGAACCGTCTGGACGAC
ATCATCGTGTTCAAGCAGCTTACCGAGCCGCAGGTGCGCCAGATCGTCGACCTTGACGTCAAGCAGCTCAACGACCGTCT
GTTCGACCGCCACATGTCGCTCGAGCTCACTGATGCCGCCAAGGACCTGCTCGCGCAGAAGGGCTTTGACCCGCTGCTCG
GTGCCCGTCCATTGCGCCGCGTGATTCAGCGCGACATCGAGGATGCCATATCGGAGAAGATTCTGATGGGCGACCTCGAA
GACGGCCAGCGCGTGAAGGTCGATGCCGAAGGCGAGGGCATTCTGGGCGAATTCACCTTCTCCGGAGAGGCGTTTGAGGA
GCCGGTGACGGCGGACGAGTCGTCTGAGTCGTCTGAGTCAGATTCCGCCGAGCCCGTCGAGGTTTCGGCCGGGATTGCCG
ATTCGGCATCGGAATCTTCCGAAACCGAATAA

Protein sequence :
MFERFTDRARRVIVLAQEEARTLQHNYIGTEHLLLGLIREGEGVAAKALASKGVSLDDTRKQVEEMIGKGNASPNGHIPF
TPHARQVLELSLREALQLGHSYIGTEHILLGLIHEGEGVGTQVLIKMDVNLGELRSATIDLIRGNSGGSQGEGKGDLANA
GGVQDRRNQSGSAILDQFGRNLTAEAASGKLDPVIGRSSEIERVMVVLSRRTKNNPVLIGEPGVGKTAVVEGLAQKINAG
DVPETLKGKQVYSLDLGSMVAGSRYRGDFEERLKKVLKEIKTRGDIVLFIDEIHTIVGAGSADGALGASDMLKPMLARGE
LQTIGATTTDEYRKYIEKDAALERRFQPIQVHEPTIAETIEILKGLRERYENHHHVTITDGALQSAAELSSRYIQDSHLP
DKAIDLIDEAGARLRIRRLTAPPELKELDAKVAKLAEEKDQAIKDQDFEKAAELRDRQEKLEAERKEKESSWREGESDVK
MVVDEDVIAEVISQTTGIPVFKLTQAESKKLMSMESELHKRIIGQDEAVSALSRSIRRARVGLKDPKRPSGSFIFAGPTG
VGKTELAKTLAEFLFDDEDALIRVDMSEFSEKYAASRLFGAPPGYVGYEEGGELTEKVRRKPFSVVLFDEIEKAHPDIFN
TLLQVLDDGHLTDGQGRKVDFKNTIIILTTNLGTRDIAKAANTGFNLGTNTESSYQRMKDQVSSELKQQFRPEFLNRLDD
IIVFKQLTEPQVRQIVDLDVKQLNDRLFDRHMSLELTDAAKDLLAQKGFDPLLGARPLRRVIQRDIEDAISEKILMGDLE
DGQRVKVDAEGEGILGEFTFSGEAFEEPVTADESSESSESDSAEPVEVSAGIADSASESSETE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_003360265.1 Negative regulator of genetic competence clpC/mecB VFG0079 Protein 0.0 57
clpC YP_003360265.1 Negative regulator of genetic competence clpC/mecB VFG0080 Protein 7e-143 51