Gene Information

Name : clpB (BDP_1996)
Accession : YP_003361393.1
Strain : Bifidobacterium dentium Bd1
Genome accession: NC_013714
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : 3.6.4.3
Position : 2263939 - 2266575 bp
Length : 2637 bp
Strand : -
Note : -

DNA sequence :
ATGGAACAAAAGTTCACCACGATGGCGCAGGAAGCCATCGGAGACGCCATTCAAAGCGCGTCCGCGGCAGGTAACGCGCA
AGTCGACACGTTGCATGTGATGGATGCGTTGCTGCGCCAGGAAAACGGTGTGATCCGCGGCCTCATCCAGGCTGCCGGCG
GCGACGTGCAAGCCATCGGCGCTGCGGTGCGCAACGCCTTGGTCGCGTTGCCGGCTGCCAGCGGTTCGACCACATCGCAG
CCGCAGGCAAGCCGTCAGCTGACCGCCGCGATCGCGCAGGCCGAAAAGGAAATGCAGGCGATGGGCGACGAATACGTCTC
CACCGAACACCTGCTCATCGGCATCGCGGCAAGCAAGCCGAACCAATCCGCGGAAATCCTTGAAAAGAACGGCGTGACCG
CCGAAGCGCTGCGCAAGGCGGTGCCGGGCGTGCGTGGCGGCGCGAAAGTGACCAGCCCCGACGCGGAAAGATCGTACAAG
GCGCTCGAAAAGTATTCCACCGACCTGACGGCCGCCGCGAAAGACGGCAAGCTCGACCCCGTGATCGGCCGCGATCAAGA
GATCCGCCGCGTCATCCAGATCCTGAGCCGGCGCACCAAGAACAATCCGGTGCTCATCGGCGAGCCGGGCGTCGGCAAAA
CCGCCGTCGTGGAAGGTCTGGCGCAGCGCATCGTCGCCGGTGACGTGCCGACCACCCTGCAGAACAAGAAGCTGATCTCG
CTCGACCTCGGCTCCATGGTCGCGGGCTCCAAGTATCGCGGCGAATTCGAGGAACGACTGAAGAGCGTGCTCGAGGAGAT
CAAGAAGTCTGACGGGCAGATCATCACCTTCATCGACGAAATCCACACCATCGTCGGTGCGGGCGCCGCCGAAGGCTCCA
TGGACGCAGGCAATATGCTCAAGCCCATGCTGGCCCGCGGCGAACTACGCCTGATCGGTGCGACCACGCTCGACGAATAT
CGAGAGAACGTCGAAAAGGATCCGGCACTGGAACGCCGCTTCCAACAGGTCTTCGTCGGCGAACCGAGCGTGGAAGACAC
GATTGCGATCCTGCGTGGTCTGAAGCAACGTTACGAGGCGCACCACAAGGTGACGATCGGCGACGATGCGCTGGTCGCCG
CCGCAACCCTGTCGAACCGGTATATCTCCGGCCGCCAGCTGCCCGACAAGGCCATCGACCTGGTCGACGAGGCAGCCGCG
CACCTGCGTATGGAACTCGACTCCTCGCCGGAGGAAATCGACGAACTGCAACGCAAGGTGACCCGCTACGAAATGGAGGA
GATGCAGCTCAAGAAGGCCGAAGACCCCGCTTCGAAGGACCGCCTCGAGAAGCTGCAGGCCGATCTGGCGGACGCCCGCG
AAAAGCTGAGCGGCCTCAAGGCACGTTGGGATGCGGAAAAGGCCGGCCACAACAAGGTCGGCGATTTGCGAGCCAAGCTC
GACGACCTGCGCGTAGAAGCCGACAAGGCCATGCGCGAAGGCGACCTGGAGAAGGCCAGCCGCATCTCGTACGGCGAGAT
CCCCGCGATTCAGAAGGAACTGGCCGCAGCGGAAGCCGCCGCCGACAACAATGACGCGAACGGCACCGCGGTCGCCGAAA
CCGAACCGATGGTGCCCGACCACGTCGATGCCGATTCCGTGGCCGGCATCGTATCCGAATGGACCGGCATCCCGGTCGGC
CGCCTCATGCAAGGCGAGAATGAAAAGCTCCTGCACATGGAGGAGTATCTCGGCAAGCGTGTGATCGGCCAGAAGGAAGC
CATCGCAGCGGTTTCGGACGCCGTGCGGCGCTCGCGTGCCGGCATCTCCGACCCGAATCGTCCGACCGGCTCGTTCCTGT
TCCTAGGCCCCACCGGCGTGGGCAAGACCGAACTGGCCAAGGCGCTCGCGGACTTCCTGTTCGACGACGAGAAGGCCATG
GTGCGCATCGACATGAGCGAATACATGGAAAAGGCCTCCGTGTCTCGCCTGATCGGCGCCGCGCCGGGCTACATCGGCTA
CGAGGAGGGCGGCCAGCTCACCGAGGCCGTACGCCGCCGTCCATACTCGGTGGTGCTGTTCGACGAGGTGGAGAAAGCCA
ATCCGGAAGTATTCGACGTGCTGCTGCAAGTGCTCGACGATGGCCGTCTGACCGATGGTCAGGGCCGTACCGTGGACTTC
AAGAACACGATTCTGATCATGACCTCCAATTTGGGGTCGCAATTCCTCGTCAATCCGGACTTGGATGCGGACGCCAAGAA
GAAGGCCGTGATGGATGCCGTGCACATGCAGTTCAAGCCGGAATTCATCAACCGCTTGGACGAGCTGGTCATGTTCCACC
CGCTCACCCGTGAGGAACTGGGCGGCATCGTGGACATCCAGGTGGCGCAGGTCTCCGCTCGCCTGACCGAGCGTCGCATC
ACGCTCGATGTGACCGATTCGGCACGCGAATGGCTGGCCAACACCGGCTACGATCCGGCGTATGGCGCTCGCCCGCTGCG
TCGCCTGGTGCAGACCGAGGTCGGCGATCAGCTGGCGCGCATGCTGCTGGCTGGCCAGGTGCATGACGGCGACACCGTGT
TGGTGGATCAGACCGGCGGCGATCATCTCGAACTGTCCGCATGGGCGAGCGATCAACTGGCGGACATGGGCAAGTAA

Protein sequence :
MEQKFTTMAQEAIGDAIQSASAAGNAQVDTLHVMDALLRQENGVIRGLIQAAGGDVQAIGAAVRNALVALPAASGSTTSQ
PQASRQLTAAIAQAEKEMQAMGDEYVSTEHLLIGIAASKPNQSAEILEKNGVTAEALRKAVPGVRGGAKVTSPDAERSYK
ALEKYSTDLTAAAKDGKLDPVIGRDQEIRRVIQILSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVAGDVPTTLQNKKLIS
LDLGSMVAGSKYRGEFEERLKSVLEEIKKSDGQIITFIDEIHTIVGAGAAEGSMDAGNMLKPMLARGELRLIGATTLDEY
RENVEKDPALERRFQQVFVGEPSVEDTIAILRGLKQRYEAHHKVTIGDDALVAAATLSNRYISGRQLPDKAIDLVDEAAA
HLRMELDSSPEEIDELQRKVTRYEMEEMQLKKAEDPASKDRLEKLQADLADAREKLSGLKARWDAEKAGHNKVGDLRAKL
DDLRVEADKAMREGDLEKASRISYGEIPAIQKELAAAEAAADNNDANGTAVAETEPMVPDHVDADSVAGIVSEWTGIPVG
RLMQGENEKLLHMEEYLGKRVIGQKEAIAAVSDAVRRSRAGISDPNRPTGSFLFLGPTGVGKTELAKALADFLFDDEKAM
VRIDMSEYMEKASVSRLIGAAPGYIGYEEGGQLTEAVRRRPYSVVLFDEVEKANPEVFDVLLQVLDDGRLTDGQGRTVDF
KNTILIMTSNLGSQFLVNPDLDADAKKKAVMDAVHMQFKPEFINRLDELVMFHPLTREELGGIVDIQVAQVSARLTERRI
TLDVTDSAREWLANTGYDPAYGARPLRRLVQTEVGDQLARMLLAGQVHDGDTVLVDQTGGDHLELSAWASDQLADMGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-104 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 4e-106 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 3e-106 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_003361393.1 ATP-dependent chaperone ClpB VFG2084 Protein 3e-110 43
clpB YP_003361393.1 ATP-dependent chaperone ClpB VFG2076 Protein 3e-116 41