Gene Information

Name : tcsR (LLKF_1744)
Accession : YP_003354153.1
Strain : Lactococcus lactis KF147
Genome accession: NC_013656
Putative virulence/resistance : Virulence
Product : two-component system regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 1804581 - 1805273 bp
Length : 693 bp
Strand : -
Note : tcsR5

DNA sequence : 
ATGACTTCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCGCGATTCGTCTCATTAGAATTAGAACATGAAGG
CTATGCGACTGAGATTAAAGATAATGGTCGTTCTGGTCTTGAAGAAGCAAGTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTTGACGGTTTTGAGGTAGCTCGTCGTTTACGAAAAGAAAAAGATACACCAATCATTATGATG
ACGGCACGTGATTCAACGATGGACCGTGTTGCTGGTCTTGATATTGGGGCTGATGATTATATCACTAAACCTTTTGCGAT
TGAGGAACTTTTGGCGCGTGTTCGTGCTTTCTTCCGTCGTGAAGAGCATGGTCATGCCGTTGAACGTGCTGAAAATACTT
CTTTCCGTGATCTTGTGATTGACAAAACGAATCGCACCGTTCATCGTGGTAAAAAAGTAATTGATTTAACACGTCGTGAG
TATGACCTCCTTTTGACATTGATGCAAAATGTTGGCGATGTTGTGACTCGTGAACATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACAGAAACAAATGTTGTGGATGTTTATATTCGTTATCTTAGAAATAAAATTGATGTTGAAGGTCAAGATA
GCTATATTCAAACTGTTCGTGGCTTAGGTTATGTAATGCGTGAACGCAAATAA

Protein sequence : 
MTSKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEASSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHGHAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 4e-31 46
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-30 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tcsR YP_003354153.1 two-component system regulator HE999704.1.gene1528. Protein 2e-56 63
tcsR YP_003354153.1 two-component system regulator NC_003923.1003417.p0 Protein 2e-44 52
tcsR YP_003354153.1 two-component system regulator NC_013450.8614146.p0 Protein 2e-44 52
tcsR YP_003354153.1 two-component system regulator NC_002951.3238224.p0 Protein 2e-44 52
tcsR YP_003354153.1 two-component system regulator NC_007793.3914065.p0 Protein 2e-44 52
tcsR YP_003354153.1 two-component system regulator NC_002758.1121390.p0 Protein 2e-44 52
tcsR YP_003354153.1 two-component system regulator NC_010079.5776364.p0 Protein 2e-44 52
tcsR YP_003354153.1 two-component system regulator NC_002952.2859858.p0 Protein 2e-44 52
tcsR YP_003354153.1 two-component system regulator NC_007622.3794948.p0 Protein 2e-44 52
tcsR YP_003354153.1 two-component system regulator AE015929.1.gene1106. Protein 6e-42 52
tcsR YP_003354153.1 two-component system regulator BAC0308 Protein 1e-32 45
tcsR YP_003354153.1 two-component system regulator BAC0125 Protein 1e-31 44
tcsR YP_003354153.1 two-component system regulator NC_012469.1.7685629. Protein 6e-35 44
tcsR YP_003354153.1 two-component system regulator BAC0197 Protein 4e-32 43
tcsR YP_003354153.1 two-component system regulator AE016830.1.gene1681. Protein 3e-34 42
tcsR YP_003354153.1 two-component system regulator BAC0111 Protein 4e-31 42
tcsR YP_003354153.1 two-component system regulator NC_012469.1.7686381. Protein 1e-34 41
tcsR YP_003354153.1 two-component system regulator BAC0083 Protein 3e-31 41
tcsR YP_003354153.1 two-component system regulator HE999704.1.gene2815. Protein 1e-33 41
tcsR YP_003354153.1 two-component system regulator BAC0638 Protein 1e-25 41
tcsR YP_003354153.1 two-component system regulator AE000516.2.gene3505. Protein 3e-27 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tcsR YP_003354153.1 two-component system regulator VFG0596 Protein 1e-31 46
tcsR YP_003354153.1 two-component system regulator VFG1390 Protein 5e-41 45
tcsR YP_003354153.1 two-component system regulator VFG1389 Protein 2e-32 41