Gene Information

Name : pyk (LLKF_1423)
Accession : YP_003353857.1
Strain : Lactococcus lactis KF147
Genome accession: NC_013656
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1490596 - 1492104 bp
Length : 1509 bp
Strand : -
Note : pyk1

DNA sequence :
ATGAATAAACGTGTAAAAATCGTCTCAACTCTTGGACCTGCTGTCGAAATTCGTGGTGGCAAAAAATTTGGTGAAAGCGG
CTATTGGGGAGAATCTCTTGACGTCGAAGCATCAGCAAAAAACATTGCAGCTTTGATTGAAGAAGGCGCAAATGTCTTCC
GTTTCAACTTCTCACACGGTGACCATCCTGAACAAGGTGCTCGTATGGCAACAGTTCACCGCGCTGAAGAAATCGCTGGT
CATAAAGTAGGTTTCTTGCTTGATACTAAAGGTCCTGAAATGCGTACAGAACTCTTTGCTGACGGTGCTGATGCAATCAG
CGTTGTTACTGGAGATAAATTTCGCGTTGCAACTAAACAAGGTCTTAAATCAACTCCTGAATTGATTGCTTTGAACGTAG
CTGGTGGTCTTGATATCTTTGATGATGTTGAAATTGGTCAAACTATTTTGATTGACGATGGTAAACTTGGTTTGTCATTG
ACTGGTAAAGATGCAGCAACTCGAGAATTTGAAGTTGAAGCACAAAATGATGGTGTTATTGGTAAACAAAAAGGTGTTAA
TATTCCTAACACTAAAATTCCTTTCCCAGCTCTTGCTGAACGTGATGATGCGGATATCCGTTTCGGACTTTCACAACCTG
GTGGAATCAACTTTATCGCTATCTCATTCGTACGTACTGCAAATGACGTTAAAGAAGTACGTCGTATTTGTGAAGAAACT
GGAAATCCACACGTACAACTTTTGGCTAAAATTGAAAACCAACAAGGTATCGAAAACCTTGATGAAATCATCGAAGCAGC
TGATGGTATCATGATCGCTCGTGGTGACATGGGTATCGAAGTTCCATTTGAAATGGTTCCAGTTTACCAAAAATTGATCA
TCAGCAAAGTTAACAAAGCAGGTAAAATCGTTGTTACTGCAACAAACATGCTTGAATCAATGACTTACAACCCACGTGCT
ACACGTTCAGAAATTTCAGACGTATTCAACGCTGTTATTGACGGAACTGACGCAACAATGCTTTCAGGTGAATCTGCTAA
CGGTAAATACCCACGCGAATCAGTTCGTACAATGGCTACTGTTAACAAAAACGCTCAAACAATGTTGAAAGAATACGGAC
GTCTTCACCCAGAACGTTACGACAAATCAACTGTAACAGAAGTAGTTGCTGCATCAGTTAAAAATGCTGCAGAAGCTATG
GATATCAAATTGATTGTTGCTTTGACTGAATCAGGTAACACTGCTCGTTTGATTTCTAAACACCGTCCTAATGCTGACAT
CTTGGCTATTACATTTGACGAAAAAGTTGAACGTGGATTGATGATTAACTGGGGTGTAATCCCAACGATGACTGAAAAAC
CTTCATCTACAGATGATATGTTTGAAGTTGCTGAAAAAGTTGCTTTGGCTTCAGGTTTAGTTGAATCTGGTGACAATATC
ATCATCGTTGCTGGTGTTCCAGTTGGTACTGGTCGTACAAATACAATGCGTATCCGCACTGTTAAATAA

Protein sequence :
MNKRVKIVSTLGPAVEIRGGKKFGESGYWGESLDVEASAKNIAALIEEGANVFRFNFSHGDHPEQGARMATVHRAEEIAG
HKVGFLLDTKGPEMRTELFADGADAISVVTGDKFRVATKQGLKSTPELIALNVAGGLDIFDDVEIGQTILIDDGKLGLSL
TGKDAATREFEVEAQNDGVIGKQKGVNIPNTKIPFPALAERDDADIRFGLSQPGGINFIAISFVRTANDVKEVRRICEET
GNPHVQLLAKIENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKLIISKVNKAGKIVVTATNMLESMTYNPRA
TRSEISDVFNAVIDGTDATMLSGESANGKYPRESVRTMATVNKNAQTMLKEYGRLHPERYDKSTVTEVVAASVKNAAEAM
DIKLIVALTESGNTARLISKHRPNADILAITFDEKVERGLMINWGVIPTMTEKPSSTDDMFEVAEKVALASGLVESGDNI
IIVAGVPVGTGRTNTMRIRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-76 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-77 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-77 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-77 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_003353857.1 pyruvate kinase VFG0479 Protein 4e-77 42