Gene Information

Name : Tnap_0838 (Tnap_0838)
Accession : YP_003346344.1
Strain : Thermotoga naphthophila RKU-10
Genome accession: NC_013642
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 874522 - 875922 bp
Length : 1401 bp
Strand : -
Note : KEGG: tpt:Tpet_0716 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence :
GTGCGAAATACAAAGATCGTGTGTACGGTTGGACCAAGAACAGACAGCTACGAAATGATAGAAAAGATGATAGATCTTGG
AGTGAACGTCTTCAGAATAAACACCTCACACGGCGACTGGAACGAACAGGAACAGAAAATACTCAAAATCAAAGAGTTGA
GAGAGAAAAAGAAAAAACCCGTAGCCGTTCTGATCGATCTTGCGGGTCCGAAGATCAGAACTGGATATCTCGAAAAAGAG
TTTGTAGAATTGAAAGAGGGCCAGATCTTCACTCTCACCACAAAGGAAATACTTGGAAACGAACATATGGTTTCGGTGAA
CCTCAGTTCTCTTCCACAGGACGTGAAAAAAGGAGACACCATTCTGTTGAGCGATGGAGAAATAGTGCTTGAAGTAATTG
AAACGACCGATACAGAAGTGAAAACAGTGGTGAAAGTCGGTGGAAAGATCACACACAGGAGAGGTGTGAACGTACCAACA
GCCGACCTCTCGGTGGAATCCATAACGGACAGAGACAGAGAATTCATAAAGCTCGGAACATTGCACAATGTTGAATTTTT
CGCTCTTTCTTTTGTGAGAAAACCAGAGGACGTGCTCAAGGCAAAAGAAGAGATCAGAAAACACGGAAGCGAAATACCTG
TAATCTCTAAAATAGAAACGAAAAAGGCCCTGGAACGTCTCGAAGAGATAATAAAGGTAAGCGATGGAATCATGGTCGCA
CGCGGTGACCTGGGAGTGGAGATACCCATAGAAGAAGTTCCTATCGTTCAAAAAGAAATCATCAAACTCTCCAAGTACTA
CTCCAAACCAGTTATAGTCGCAACTCAAATACTCGAATCGATGATAGAAAATCCGTTTCCCACGAGGGCAGAGGTCACCG
ACATAGCCAACGCCATCTTTGATGGAGCGGACGCCCTGCTTCTCACAGCGGAAACAGCGGTTGGAAAACATCCCCTGGAA
GCCATAAAAGTGTTGAGCAAAGTAGCAGAAGAGGCCGAAAAAAAGCTGGAATTTTTCAGAACGATAGAATACGATACCAG
CGACATATCTGAGGCCATATCACACGCCTGCTGGCAGCTCTCTGAATCTCTAAACGCGAAGCTGATCATCACACCCACCA
TATCCGGGAGTACCGCCATTCGTGTCTCGAAGTACAACGTTTCTCAACCCATTGTGGCTCTGACACCAGAAGAGAAAACC
TACTACAGACTTTCTCTCGTGAGGAAAGTGATACCCGTTCTCGCCGAAAAGTGCTCTCAGGAGCTGGAGTTCATCGAAAA
AGGATTGAAGAAAGTGGAAGAAATGGGTTTAGCAGAAAAAGGGGATCTGGTGGTTCTCACTTCCGGCGTTCCAGGGAAGG
TGGGAACGACGAACACCATACGGGTGTTGAGGGTGGATTGA

Protein sequence :
MRNTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKELREKKKKPVAVLIDLAGPKIRTGYLEKE
FVELKEGQIFTLTTKEILGNEHMVSVNLSSLPQDVKKGDTILLSDGEIVLEVIETTDTEVKTVVKVGGKITHRRGVNVPT
ADLSVESITDRDREFIKLGTLHNVEFFALSFVRKPEDVLKAKEEIRKHGSEIPVISKIETKKALERLEEIIKVSDGIMVA
RGDLGVEIPIEEVPIVQKEIIKLSKYYSKPVIVATQILESMIENPFPTRAEVTDIANAIFDGADALLLTAETAVGKHPLE
AIKVLSKVAEEAEKKLEFFRTIEYDTSDISEAISHACWQLSESLNAKLIITPTISGSTAIRVSKYNVSQPIVALTPEEKT
YYRLSLVRKVIPVLAEKCSQELEFIEKGLKKVEEMGLAEKGDLVVLTSGVPGKVGTTNTIRVLRVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-69 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-69 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-69 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-69 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tnap_0838 YP_003346344.1 pyruvate kinase VFG0479 Protein 2e-69 42