Gene Information

Name : Sros_8961 (Sros_8961)
Accession : YP_003344335.1
Strain : Streptosporangium roseum DSM 43021
Genome accession: NC_013595
Putative virulence/resistance : Resistance
Product : beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2602
EC number : 3.5.2.6
Position : 9907846 - 9908754 bp
Length : 909 bp
Strand : -
Note : KEGG: rpi:Rpic_3962 beta-lactamase

DNA sequence :
ATGCAGCATTCCTCCGACTCCGCCCGCCGGCGGCGGGTCCGGACGACACTGGGCGTCGCCGTCCTGACGGCGTCCGCGCT
GTTCGGCGGGACCGCCGCCCACGGCGCCGCGGGTCCTTCCGGCGGCGGGACCGCCGCCGCCGGGACCGCGGCGGCGCAGT
CCGCGGTCCAGCAGCGGACGATCGTCCGGGACGACCTGCAGGCGCTGTTCCGCCAGGCGGGGGTGCGCGGCACGTTCGCC
CTCCTGGATGTGAAGACCGGGCAGACCACGGTGGTCGACCGGCGCAGGGCGGAGCAGCGGCTGATCCCCGCGTCCACCTT
CAAGGTCCCGCACGCCCTGATCGCGCTGGAGACCGGTGCCGTCAAGGACGAGAACGAGGTGATCCCGTACGGAGGAAAGC
CGCAGCCGTTCCCGGAGTGGGAGCAGGACATGAACCTGCGCGACGCGATCCGGGTGTCCAACGTCCCCGTCTTCCAGACG
CTCGCCCGGCGGATCGGCGTCAAGCGGGAGAAGCAGTGGGTGAACCGGCTCGGTTACGGCAACCGCCAGATCGGCTCCGT
GGTCGACCAGTTCTGGCTTGAGGGCCCGCTGGAGATCTCGGCGACGGAGCAGACCCGCTTCCTGTCGCGGATGGCCCGCG
GGCAGCTGCCGGCCTCCCAGCGCAACCAGCGGACGGTGCGCGAGCTGCTGAAGATCGAGGAGAAGGACGGCTACACCCTG
TACGCCAAGACCGGCTGGGGCATGTCCACCAAGCCGGGCATCGGCTGGTGGGTGGGCTGGATCGAGCGCGGCGACCGGCT
CTACACCTTCGCGCTCAACATCGACGTCAACGCCGACGAGGACACCAAGAAGCGGATCCCGCTCGCCCGCGAGCTGCTGA
GCCGCCTCGGCGCACTCCCGGCCGCCTGA

Protein sequence :
MQHSSDSARRRRVRTTLGVAVLTASALFGGTAAHGAAGPSGGGTAAAGTAAAQSAVQQRTIVRDDLQALFRQAGVRGTFA
LLDVKTGQTTVVDRRRAEQRLIPASTFKVPHALIALETGAVKDENEVIPYGGKPQPFPEWEQDMNLRDAIRVSNVPVFQT
LARRIGVKREKQWVNRLGYGNRQIGSVVDQFWLEGPLEISATEQTRFLSRMARGQLPASQRNQRTVRELLKIEEKDGYTL
YAKTGWGMSTKPGIGWWVGWIERGDRLYTFALNIDVNADEDTKKRIPLARELLSRLGALPAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaOXA-129 AET25386.1 OXA-129 beta-lactamase Not tested PAGI-2(C) Protein 1e-45 42
bla OXA-129 AFG30109.1 OXA-129 beta-lactamase Not tested PAGI-2 Protein 1e-45 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sros_8961 YP_003344335.1 beta-lactamase AY306130.1.gene1.p01 Protein 4e-63 56
Sros_8961 YP_003344335.1 beta-lactamase JF273470.1.gene1.p01 Protein 3e-46 43
Sros_8961 YP_003344335.1 beta-lactamase EU086834.1.gene1.p01 Protein 2e-46 43
Sros_8961 YP_003344335.1 beta-lactamase EU086830.1.gene1.p01 Protein 3e-46 43
Sros_8961 YP_003344335.1 beta-lactamase AY423074.1.gene1.p01 Protein 7e-48 43
Sros_8961 YP_003344335.1 beta-lactamase AY619003.1.gene1.p01 Protein 7e-43 42
Sros_8961 YP_003344335.1 beta-lactamase X58272.1.gene1.p01 Protein 6e-45 42
Sros_8961 YP_003344335.1 beta-lactamase AM932669.1.gene2.p01 Protein 8e-46 42
Sros_8961 YP_003344335.1 beta-lactamase AY343493.1.gene1.p01 Protein 3e-40 42
Sros_8961 YP_003344335.1 beta-lactamase HM113558.1.gene1.p01 Protein 9e-40 41
Sros_8961 YP_003344335.1 beta-lactamase EU220744.1.gene1.p01 Protein 3e-36 41