Gene Information

Name : Sros_3774 (Sros_3774)
Accession : YP_003339439.1
Strain : Streptosporangium roseum DSM 43021
Genome accession: NC_013595
Putative virulence/resistance : Virulence
Product : (2,3-dihydroxybenzoyl)adenylate synthase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 4198284 - 4199897 bp
Length : 1614 bp
Strand : +
Note : KEGG: scl:sce3880 (2,3-dihydroxybenzoyl)adenylate synthase

DNA sequence : 
ATGATGCCCGGATGTGTGGAGTGGCCGGAAGAGGTGGCCGCGCGTTACCGGAGGGAGGGCTACTGGCGCGGTGAGACGCT
CGGCGACCTGCTGCGCCGCGTGGCCGCGGCCCACGGCCCCCGGACCGCCCTGGTGTCGGGGGACTCGCGCTGGAGCTACC
GGGAGCTGGACGAGCGCGCCGACCGCCTCGCGGCGGGCCTGGGCGGACTCGGCATAGGCTCCGGCGACCGCGTGCTGGTC
CAGCTGCCCAACATCCCGGACCTCGTGTTCCTCTGCTTCGCGCTGTTCCGCCTCGGGGCGGCGCCGGTCCTCGCCCTGCC
GCCCCACCGGCACAGCGAGATAGGCCACCTGGCCGCCGCCACCGACGCCGTCGCCTACGTCGTCCCCGACACCTGCCAGG
GTTTCGACCACCGGGAACTCGCCCGGCGGGTGCAGGCGTCGGCGCCGTCGCTCCGCCACGTCATCGTGTCCGGCGACCCG
CAGGAGTTCACGGCCCTGGCCGACCTCGAACGCGACCCCGTGCCGCACGACTCCCCCGATCCCGGCGACGTGGCCCTGTT
CCTGCTGTCGGGCGGGACCACCGGCCGCTCCAAGCTCATCCCGCGCACCCACGACGACTACGCCTGCAACATCCGGCTCA
GCGCGGAGAACGCCGGCCTGGACGAGACGTCGGTCTACCTGGCCGCCCTGCCGATCGCGCACAACTACGCGCTCGGCTGC
CCCGGAGTGCTCGGCACGCTGCAGGCGGGCGGGACGGTCGTCCTCACCCCGACCCCGAGCCCCGACGACGCCTTCCCGCT
GATCGAGCGCGAGCGGGTCACCGTCACGGGCCTCGTCCCCTCACTCGCCCAGCTGTGGGCGGAGGCGGCGGAGTGGGCCC
GGCGGGACCTGTCCAGCCTCCGCCTGGTCCAGGTCGGCGGTGCCGCGGTCTCGGGCGAGCTGGCCGGCCGGGTGGGCAGG
ACACTGGGCCGTCTCCAGCAGTCCTTCGGGATGGCCGAGGGGCTGCTCAGCCAGAGCCGCGGCGACGACTCCGCGGAGCT
GCTCGTGTCCACGCAGGGCAAGCCGCTCGCCCAGGCCGACGAGGTGCGCCTCGTCGGCGACGACGGCCGCGACGTCCCGC
CGGGAGAGGCCGGCGAGCTCCTGGTCCGCGGCCCCTACACCATCCGCGGCTACTACCGTGCGCCCGAGCACAACGCCGCC
GCCTTCACCCCGGACGGGTTCTTCCGCAGCGGCGACCTCGCCCGGCTGACCGGCACCGGCCATCTCGCCATCGTCGGACG
GGTCAAGGACGTGATCAACAGGGGCGGCGACAAGGTGCCCGCCGACGAGGTGGAGGACCACCTCCTCGCCCACCCCGAAG
TCGACGCCGTGGCGGTGGTCGCGATGCCCGACCCGTTGCTGGGGGAGCGGACCTGCGCCTACATCGTCCCCCGCAGGAAG
GCCCCGAGCCTGAAGACGATCGAGGCGTTCCTCCGCAAACGAGGCGTGGCCGCCTACAAGGTCCCCGACTGGATCGAGGA
CGTCGCCGCCCTGCCGTACACCCCGGTGGGAAAGATCGACAAGGCCCGCCTGCGCGCGGACATCGCCCATCGGCGGGGCG
GCAGGCGGCCGTGA

Protein sequence : 
MMPGCVEWPEEVAARYRREGYWRGETLGDLLRRVAAAHGPRTALVSGDSRWSYRELDERADRLAAGLGGLGIGSGDRVLV
QLPNIPDLVFLCFALFRLGAAPVLALPPHRHSEIGHLAAATDAVAYVVPDTCQGFDHRELARRVQASAPSLRHVIVSGDP
QEFTALADLERDPVPHDSPDPGDVALFLLSGGTTGRSKLIPRTHDDYACNIRLSAENAGLDETSVYLAALPIAHNYALGC
PGVLGTLQAGGTVVLTPTPSPDDAFPLIERERVTVTGLVPSLAQLWAEAAEWARRDLSSLRLVQVGGAAVSGELAGRVGR
TLGRLQQSFGMAEGLLSQSRGDDSAELLVSTQGKPLAQADEVRLVGDDGRDVPPGEAGELLVRGPYTIRGYYRAPEHNAA
AFTPDGFFRSGDLARLTGTGHLAIVGRVKDVINRGGDKVPADEVEDHLLAHPEVDAVAVVAMPDPLLGERTCAYIVPRRK
APSLKTIEAFLRKRGVAAYKVPDWIEDVAALPYTPVGKIDKARLRADIAHRRGGRRP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 5e-96 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-96 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 3e-97 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 5e-97 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-97 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 4e-97 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-97 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-97 50
ybtE CAA21394.1 - Virulence HPI Protein 4e-97 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sros_3774 YP_003339439.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG0168 Protein 1e-106 51
Sros_3774 YP_003339439.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG1817 Protein 5e-94 50
Sros_3774 YP_003339439.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG0932 Protein 5e-94 46