Gene Information

Name : Sros_2953 (Sros_2953)
Accession : YP_003338651.1
Strain : Streptosporangium roseum DSM 43021
Genome accession: NC_013595
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3215252 - 3216682 bp
Length : 1431 bp
Strand : +
Note : KEGG: mxa:MXAN_6299 pyruvate kinase

DNA sequence :
GTGACCCGTCGCGCAAAAATCGTCTGTACTCTCGGCCCTGCCACCTCCTCTCCCGAACGCCTCCGCGAGCTCATCGCCGC
GGGCATGGACGTGGCCCGTTTCAACCTCAGCCATGGCAGCCACGAGCTGCACAAGGAGGTCTACGACAGGGTGAGGGAGG
CCGCCGCCGAGCTCGGCCGCGGCGTAGGCGTGCTGGCCGACCTGCAGGGCCCCAAGATCCGGGTGGGCAAGTTCGAGGAG
GGGCCGGTCCGTCTCGGCTTCGGTGACGTCTTCACCGTCACCACCGAGGAGGTCCCCGGGGACCGGGAGCAGGTCTCCAC
GACCTACCTCGGCCTGCCCAACGACGTCCGCCCGGGCGACAGCATCCTCGTCGACGACGGCCGCGTCCACCTGGAGGTGA
CCAGGGTCGACGGCCCGCGCGTCACCACCCGGGTGATCATCGGCGGCATGATCTCCGACAACAAGGGCCTCAACCTGCCC
GGCGTCAACGTCAGCGCGCCCGCCCTCACCGACAAGGACGAGACCGACCTCCGCTGGGCCCTGCGCACCGGGTTCGACCT
CATCGCGCTCTCCTTCGTCCGCCGTCCCTCCGATGCCGACGTGGTGCGCAACATCATGGAGCAGGAGGCCGTCCGCCTCC
CGCTGCTCGCCAAGATCGAGAAGCCGCAGGCCGTGGAGCGGCTGCCCGAGATCATCGAGGCCTTCGACGGCATCATGGTC
GCCCGCGGCGACCTCGGCGTCGAGCTGCCCCTCGAAGAGGTGCCGATCGTCCAGAAGCGCGCCATCGAGCTCTGCCGCGA
GAAGGCCCGCCCGGTCATCGTCGCCACCCAGATGCTCGACTCGATGATCAGCTCACCGCGCCCCACCCGGGCCGAGGCCT
CCGACGTCGCCTACGCGGTCATGGACGGCGCCGACGCGGTCATGCTCTCCGGCGAGACCTCGGTCGGCAACTACCCCATC
GAGTCCGTGCAGACCATGAGCCGCATCGCGACCACCGCGGAGAAGACCTCGCTGCAGGCCACCCACAGCCTGGACCGGCT
GCCGGAGACCACCGGCGGGGCCATCGCCCGTGCCGCCGCCGAGGTCGGCGCCATCGTCGGGGCCAAGGCCCTGGTCGCGT
TCACCATGTCCGGTGAGACCGCCCGCCGCCTGGCGCGCTACCGCTCGCCGATCCCGCTGCTGGCCTTCACCTCCTCCCCG
CACGTCCGCTGCCAGCTCGCGCTGACGTGGGGTGTGGAGACCTTCGAGGTGCCGTTCGTCCACCACACCGACGACATGGT
CCGCCAGGTCGAGGCCTCCCTGCTGGCCAACGCGCGGCTGGAGAAGGGCGACAAGGTCGTCATCGTCGCCGGCTCGCCTC
CCGGCACCGCCGGTTCCACCAACGCCCTGCGCGTCCACACCATCGGCTCGGCGGTCTCCCACCCCGCCTGA

Protein sequence :
MTRRAKIVCTLGPATSSPERLRELIAAGMDVARFNLSHGSHELHKEVYDRVREAAAELGRGVGVLADLQGPKIRVGKFEE
GPVRLGFGDVFTVTTEEVPGDREQVSTTYLGLPNDVRPGDSILVDDGRVHLEVTRVDGPRVTTRVIIGGMISDNKGLNLP
GVNVSAPALTDKDETDLRWALRTGFDLIALSFVRRPSDADVVRNIMEQEAVRLPLLAKIEKPQAVERLPEIIEAFDGIMV
ARGDLGVELPLEEVPIVQKRAIELCREKARPVIVATQMLDSMISSPRPTRAEASDVAYAVMDGADAVMLSGETSVGNYPI
ESVQTMSRIATTAEKTSLQATHSLDRLPETTGGAIARAAAEVGAIVGAKALVAFTMSGETARRLARYRSPIPLLAFTSSP
HVRCQLALTWGVETFEVPFVHHTDDMVRQVEASLLANARLEKGDKVVIVAGSPPGTAGSTNALRVHTIGSAVSHPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 2e-65 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-70 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-70 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-70 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sros_2953 YP_003338651.1 pyruvate kinase VFG0479 Protein 1e-70 41