Gene Information

Name : Dd586_2818 (Dd586_2818)
Accession : YP_003334363.1
Strain : Dickeya dadantii Ech586
Genome accession: NC_013592
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 3190348 - 3191976 bp
Length : 1629 bp
Strand : +
Note : TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: dze:Dd1591_1317 2,3-dihydroxybenzoate-AMP ligase

DNA sequence : 
ATGATGGTTGAATTCACCCGCTGGCCGCCCGAGCTGGAGCAGCGTTATCGCGAGCGGGGCTACTGGCTGGATCTCCCGCT
GGGCGACATCCTCACCCGTCATGCTGATAATGACGCCATCGCCCTGATCGATGGCGAACGCACGCTCAGCTACCGCCAGA
TGAACCAACTGGTGGCGCAATTAGCTGGCTCACTGCAACGCCAGGGCATCACCCCAGGGCAAACGGCGCTGGTACAACTA
GGCAATATCGCCGAGTTCTACCTGACGTACTTCGCGCTGCTGCGTGCCGGTATCGTGCCGGTCAACGCCCTGTTCAGCCA
TCAGCGCAGCGAGCTGTGCGCCTATGCCGACCAGATTGCGCCAACGCTGCTGATAGCCGATCGCAGCCACGCATTGTTTG
CCAGCGATGATTTTATCAACGAACTACGCCAACGCTGCCCCACGTTACAGCACGTTCTGCTGCGTGGTGATGGCGACACG
TCTCAGGATTTGTCACAGTTGCTGCTGGAAGCGGAAGCCTTCGCACCAGCAACCCCGACACCCGCCGATCAGGTGGCATT
CTTCCAGCTTTCCGGCGGTAGCACCGGCACCCCGAAACTGATTCCTCGTACCCACAACGATTACTACTACAGCATCCGCG
GCAGCGTGGAGATTTGCCGGGTTGACGCACATACCCGTTTCCTGTGCGCCCTGCCCGCCGCCCACAACTACCCGCTCAGT
TCGCCGGGCGCACTGGGTGTGTTTTATGCCGGGGGCACGGTCGTGCTGGCAAGCGACCCCAGCCCAGCCTGCTGTTTCCC
GTTGATTGCGCAGCACCGCATCACCCTCACCGCGCTGGTCCCCCCAGCTGTCACACTGTGGCTGGAAGCGGTGGCGTTAT
CCGGCGATCGCCACGCGCTGGCAAGCCTGCGCGTACTGCAGGTCGGTGGTGCTCGGTTAAGCGAATCGCTGGCACGGCGC
ATACCAACAGAGCTGGGTTGCCAGTTACAGCAAGTGTTCGGCATGGCCGAAGGGCTGGTGAATTACACCCGGCTGGACGA
TGACGATGTCCACTGCTTTACCACGCAGGGCTGCCCGATCAGCGACGATGACGAGGTCTGGGTAGCCGATGCCGACGGCA
ACCCATTGCCGCACGGTACACCGGGCCGTCTGATGACGCGTGGCCCCTACACCTTCCGTGGTTACTACCGCAGCCCGGCC
TACAACCGCCAGGTGTTCAACGCGCAAGGGTTCTACTGCTCCGGCGATGTGGTGATCCAACAGGCCGATGGCTACCTGCA
AGTGGTCGGGCGTGAAAAAGACCAGATCAACCGTGGCGGGGAAAAGATTGCCGCTGAAGAGATCGAAAACCTGCTGCTTC
GCCACCCCGCCGTGATCAACGCCGCGCTGGTGGCGGTGCCCGACCCGATGATGGGTGAGAAAAGCTGCGCTTTTCTGGTC
ACCCGCGAGCCACTCAAAGCGGTGACATTACGTCGCCACCTGCGTGAACAGGGTATCGCCGACTACAAATTACCGGACCG
ATTTGAACAACTGCCCACCCTGCCGGAAACCGCAGTGGGCAAAGTCGATAAACAGCGGCTACGCCAGCTGGCGCAACAGC
ACGTCGCAACGGCCGCTGCAGGAGAATAA

Protein sequence : 
MMVEFTRWPPELEQRYRERGYWLDLPLGDILTRHADNDAIALIDGERTLSYRQMNQLVAQLAGSLQRQGITPGQTALVQL
GNIAEFYLTYFALLRAGIVPVNALFSHQRSELCAYADQIAPTLLIADRSHALFASDDFINELRQRCPTLQHVLLRGDGDT
SQDLSQLLLEAEAFAPATPTPADQVAFFQLSGGSTGTPKLIPRTHNDYYYSIRGSVEICRVDAHTRFLCALPAAHNYPLS
SPGALGVFYAGGTVVLASDPSPACCFPLIAQHRITLTALVPPAVTLWLEAVALSGDRHALASLRVLQVGGARLSESLARR
IPTELGCQLQQVFGMAEGLVNYTRLDDDDVHCFTTQGCPISDDDEVWVADADGNPLPHGTPGRLMTRGPYTFRGYYRSPA
YNRQVFNAQGFYCSGDVVIQQADGYLQVVGREKDQINRGGEKIAAEEIENLLLRHPAVINAALVAVPDPMMGEKSCAFLV
TREPLKAVTLRRHLREQGIADYKLPDRFEQLPTLPETAVGKVDKQRLRQLAQQHVATAAAGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-86 43
ybtE CAA21394.1 - Virulence HPI Protein 1e-86 43
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-86 43
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-86 43
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-86 43
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-86 43
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-86 43
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 2e-85 43
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-85 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Dd586_2818 YP_003334363.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 8e-174 68
Dd586_2818 YP_003334363.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 9e-103 46
Dd586_2818 YP_003334363.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 5e-83 42