Gene Information

Name : guaA (ACIS_00208)
Accession : YP_003328198.1
Strain : Anaplasma centrale Israel
Genome accession: NC_013532
Putative virulence/resistance : Unknown
Product : bifunctional GMP synthase/glutamine amidotransferase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 179018 - 180607 bp
Length : 1590 bp
Strand : +
Note : -

DNA sequence :
ATGTCTGCCATTGCCATAGTTGACTTTGGTTCGCAAGTAACCCAGCTAATAGCCAGAAGGGTGAGGGAGCTAGGTGCATA
TAGCGAGGTGTTCCCCCCAAGTACAGATTTTCAGGCCATGATTGGCCGTGGCGCCGAAATCAGCGCTTTCGTTCTTTCTG
GGGGGCCGAATTCGGTCCAGCAACTGCATGAGGTTCCCAAAGCGGTGTCGGATGTGCTAGAGCTCAACCTCCATAAGGGC
ATACCCGTGCTAGGAATATGCTACGGTTTGCAGGTACTAGCGCACTACTTCGGAGCCGATGTAGAACAGGGTGTAGCCAG
GGAATTTGGCAGGGCTCAATTGGACGTCGTTGGTCCTTCATCCATCACCGAAGGGGTATGGTCGGTGGGTAGCAAGGCGG
ACGTGTGGATGAGCCACTCTGATAGTATAGTGGGCGAAGCGCCGCAAGGTTTTAGGGTGGTGGCGCGCAGCGCGGATACT
GGGGCTATAGCCCTTATATGTAACGATGAGCGCAAAATTTACGGCATGCAATTTCACCCAGAGGTAGCGCACACACCAGG
TGGGCGTGAAATGCTGGACAACTTCTTAAAGGTTGTGGGTTGTGCTAGAGACTGGACTATGGGGTCATTCTTGCACACCC
AGATTGATGCCATAAGGTCTGCCACCGGTGGTGGGCGCGTAGTGGCGGCTATAAGTGGAGGTGTTGACTCAAGTGTGGCG
TCAGTGCTGGTTCACAGAGCAATAGGGGAAGGGTTGCTATGCGTGTTCGTTGACACTGGTTTATTGCGCAAAGGTGAAGC
GAGTGCAGTAAGAGACCTTTTTGTTGACAAGCTCAAGATGCATGTGAATGTTCTGGATAAAAGTGACTTGTTCATGCGGC
GCCTTGCGGGCGTTCAAGACCCGGAGGCAAAGCGTAAGATCATCGGTGAGACGTTCATTGAGGTTTTTGAACAAGAGGCG
CGAGCCCTGGGTGACATCAAGTTCCTGATGCAGGGAACTATATATCCAGATGTTATAGAATCAGGCACAGGGGGATCTGG
GACGAAAATTAAATCACATCACAATGTCGGCGGGCTGCCTGAAGTCATGAACTTGTCGCTAATAGAGCCGTTGCGCTGTC
TGTTCAAGGATGAAGTGCGGTTGTTGGGTGAGGAGCTTGGCTTACCGTCAGCGATATTGGGCAGGCACCCGTTTCCAGGT
CCGGGACTAGCGGTCAGGATTATTGGGGAGGTCACGGCGGAGCGAGTTGGATTACTTAGAGAAATAGACAACATCTACAT
AAACATGATGCGCGAGGCGGGGCTATATGGCCACATATGGCAGGCGTTTGCGGTCCTGGTGCCCGTGCGCACTGTTGGTG
TTATGGGTGATGGCAGGACTTACGGGTATGTATGTGCGCTCAGGGCGGTAACTTCGAGTGATGGTATGACCGCAGACTGC
TTTCCCTTCGGTGAAGACGACGAGAGGAAATTGGAGTTCCTTACATTTTTACAGAAAGTTAGTAGGGCTATTGTAAGCAA
TCTGCAGGGGGTGAATAGGGTAGTGTACGATATAACCTCAAAGCCTCCGGCAACGATCGAGTGGGAGTGA

Protein sequence :
MSAIAIVDFGSQVTQLIARRVRELGAYSEVFPPSTDFQAMIGRGAEISAFVLSGGPNSVQQLHEVPKAVSDVLELNLHKG
IPVLGICYGLQVLAHYFGADVEQGVAREFGRAQLDVVGPSSITEGVWSVGSKADVWMSHSDSIVGEAPQGFRVVARSADT
GAIALICNDERKIYGMQFHPEVAHTPGGREMLDNFLKVVGCARDWTMGSFLHTQIDAIRSATGGGRVVAAISGGVDSSVA
SVLVHRAIGEGLLCVFVDTGLLRKGEASAVRDLFVDKLKMHVNVLDKSDLFMRRLAGVQDPEAKRKIIGETFIEVFEQEA
RALGDIKFLMQGTIYPDVIESGTGGSGTKIKSHHNVGGLPEVMNLSLIEPLRCLFKDEVRLLGEELGLPSAILGRHPFPG
PGLAVRIIGEVTAERVGLLREIDNIYINMMREAGLYGHIWQAFAVLVPVRTVGVMGDGRTYGYVCALRAVTSSDGMTADC
FPFGEDDERKLEFLTFLQKVSRAIVSNLQGVNRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-111 48
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-112 48
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-112 48
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-104 47