Gene Information

Name : Tter_2086 (Tter_2086)
Accession : YP_003323811.1
Strain :
Genome accession: NC_013526
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 215336 - 216988 bp
Length : 1653 bp
Strand : +
Note : TIGRFAM: mercuric reductase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: xau:Xaut_2903 mercuric reductase

DNA sequence : 
ATGACAACGGATGAGGCTAGGCACTACAGGATGAGGATACAGGGCATGACCTGCAGCCACTGCGCCGAGGTGGTCACGGG
GGCGCTGGAGGGAGCAGGAGCCCAGGAGGTGAGCGTGGATTACCTCAAGGGTGAGGCTAACTTCCGCTTCGCGGGGGACC
TGAGCACCCTGCGGCAGGCGGTGATCGAGGCCGGCTACGTGCCCGACGGCGTGGTCGACGTGACCCAGGAGGGGCGCGGC
GGGGCGATGCACGACGGTCACGACTACGACCTCGTGGTGGTGGGCTCGGGCGGTGCAGCCTTCGCTGGCGCCATCAGGGC
GACGGAGCTGGGCGCCCGGGTGCTCATGATCGAGAGGGGTACCGTGGGCGGTACCTGCGTCAACGTGGGTTGCATCCCCA
GCAAGTTCCTCCTGCGCTCGGCGGAGGTGTACCACGAGGCGGCCCATCACCCCTACCGTGGCGTCGAGACCCGCGCCTCC
TCGGTCGACCTGGGAGAGCTCGTCCGGCAGAAGGGGGAGCTCACCGAGCGGCTCCGCCAGGAGAAGTACCTGGACCTGAT
AGGTGAGTACGGCTGGGAGCTGGAGCTGGGCGAGGCTCGCTTCGTTGACGAGGGCACCCTGGAGGTGAACGGCCACAGGG
TGAGGGGCAGGCACTACCTGTTGGCGACTGGTGCTCGCCCCGCCGTGCCCCCGATACCGGGGCTGGAGGAGGCGGGCTAC
ATCACGAGCACCACCGCGATGGAGCTGGATCACGTCCCCGAGTCGCTGCTCATCATAGGGGCGGGGTACGTGGCGCTCGA
GCTGGGGATGGTCTTCCGCCGGCTGGGGAGCCAGGTGACGATCATGCAGCGGGGAGGCAGGATACTGAGGGAGTACGATC
CCGAGGTGTCGGATGCGGTGATGGAGGTGCTCCGGCGGGAGGGGATATCAGTGCTCACCGGGGCAAGGGTCCAGCGCGTC
CTGCGCGACGGCGGCTCCAAGCTCCTGGAGGTGCGTACCGGAGACGGCACCCTCACCCTGAGGGGAGAGGAGGTCCTCGT
GGCCACCGGCAGGAGCCCCAACGTGGAGGCGCTGGATCTCCCCGTGGCCGGCGTGCAGCTGGACGATACCGGCGCGGTAG
CCGTGGACGAGGCCCAGAGGACCACCAACCCCAGGGTGTGGGCTGCGGGCGACGTCACCCGGACGCCACAGTTCGTGTAC
GTGGCCGCCTACGAGGGCGGGCTGGCGGCGGGCAACGCGCTCACGGGCGCCAGGACCTACAGGGACCTGAGTGCCCTCCC
CAGCGTGATCTTCACCCAGCCCCAGATAGCCTCGGTGGGGATGACCGAGGCGGAGGCCAGGGCCAAGGGCCTGGAGGTCA
GGACGTCGACCCTGCCGCTGGACGCCGTGCCCAGGGCCCGGGTGAACGGGGACGGCCTGGGGCTCTTCAAGCTCGTGGCC
GAGGCCTCCTCCGACAGGCTGCTCGGCGCCCAGGTGGTGGCGGAGAACGCGGGCGACGTGATCTACGCCGCGGTGCTGGC
GACGAGGTTCGGGCTGAGGGTCTCCGACCTGCTCGACACCTTCGCCCCCTACCTCACGATGGCGGAGGGGCTCAAGCTCG
CGGCGCAGTCCTTCAGCCGCGACGTAAAGAAGCTGTCCTGCTGCGCAGCCTAG

Protein sequence : 
MTTDEARHYRMRIQGMTCSHCAEVVTGALEGAGAQEVSVDYLKGEANFRFAGDLSTLRQAVIEAGYVPDGVVDVTQEGRG
GAMHDGHDYDLVVVGSGGAAFAGAIRATELGARVLMIERGTVGGTCVNVGCIPSKFLLRSAEVYHEAAHHPYRGVETRAS
SVDLGELVRQKGELTERLRQEKYLDLIGEYGWELELGEARFVDEGTLEVNGHRVRGRHYLLATGARPAVPPIPGLEEAGY
ITSTTAMELDHVPESLLIIGAGYVALELGMVFRRLGSQVTIMQRGGRILREYDPEVSDAVMEVLRREGISVLTGARVQRV
LRDGGSKLLEVRTGDGTLTLRGEEVLVATGRSPNVEALDLPVAGVQLDDTGAVAVDEAQRTTNPRVWAAGDVTRTPQFVY
VAAYEGGLAAGNALTGARTYRDLSALPSVIFTQPQIASVGMTEAEARAKGLEVRTSTLPLDAVPRARVNGDGLGLFKLVA
EASSDRLLGAQVVAENAGDVIYAAVLATRFGLRVSDLLDTFAPYLTMAEGLKLAAQSFSRDVKKLSCCAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 4e-123 52
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 3e-123 52
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-78 45
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-78 45
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 4e-74 45
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-78 45
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 4e-74 45
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 9e-74 44
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 2e-72 44
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 8e-72 43
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 6e-72 43
merA AFG30120.1 MerA Not tested PAGI-2 Protein 6e-72 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tter_2086 YP_003323811.1 mercuric reductase BAC0651 Protein 2e-123 52
Tter_2086 YP_003323811.1 mercuric reductase BAC0224 Protein 9e-124 52
Tter_2086 YP_003323811.1 mercuric reductase BAC0652 Protein 3e-77 45
Tter_2086 YP_003323811.1 mercuric reductase BAC0653 Protein 3e-75 45
Tter_2086 YP_003323811.1 mercuric reductase BAC0650 Protein 4e-61 44