Gene Information

Name : Smon_0413 (Smon_0413)
Accession : YP_003305772.1
Strain : Streptobacillus moniliformis DSM 12112
Genome accession: NC_013515
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 484228 - 485667 bp
Length : 1440 bp
Strand : +
Note : KEGG: esa:ESA_02086 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence : 
ATGAAAATTAAAATGACTAAGGTTGTATGTACTATAGGGCCAAAAAGTGAAAAGAAAGAAGTTTTAAAACAATTAATTTT
AAGTGGAATGAATGTTATGAGATTAAACTTCTCACACGGAGATTTTGAAGAACATGGAAATAGAATTAAAACTATAAGAG
AAATATCAAAAGAAACAGGAAAGCATGTTGCAATTTTATTAGACACTAAAGGACCAGAAATTAGAACAGGTTCTCATGCT
GAAGGTGACGTTAAATATGAATTAGTTGAAGGACAAGATTTCATAGTTACTACAGATTATGAATTTAAAGGAACACCTGA
AAAAATTTCAGTTTCTTACCCTAACATGACTAAAGACTTAAAACCAGGAGATACTATATTAATAGATGATGGATTAATAG
GTTTAGAAGTTAAGAAAATAGAAGGAAATGAAATTTTCTGTAAAGTTAAAAACTCTGGAGCATTAGGGCAAAAGAAAGGT
GTTAACTTACCAGGAGTATCAGTTTCATTACCAGCTTTAGCTGAAAAAGATAAAGGAGATTTAAAATTCGGTTGTGAAGT
TGGAGTTGACTTTATAGCTGCTTCATTTATAAGAAAGGCATCAGACGTTGCTGAAGTTAGAAGAGTTTTAGATGAAAATG
GTGGAGAACATATTAAAATAATTTCTAAGATAGAAAATCAAGAAGGTATAGATAACTTTGATGAAATATTAGAATTATCT
GATGGAATCATGGTTGCAAGAGGAGATTTAGGAGTAGAAATTCCAGTAGAAGAAGTTCCATTTGCACAAAAAATGATGAT
CAAAAAATGTAATGCAGCTGGTAAACCAGTAATTACAGCAACACAAATGTTAGATTCTATGCAAAAAAATCCAAGACCTA
CAAGAGCAGAAGCAGGAGATGTTGCTAATGCGATTTTAGATGGAACAGATGCAGTTATGTTATCTGGGGAATCTGCAAAC
GGTAAATATCCAGTAGAAGCTGTTAAAACTATGGCTACAATTTCTGCTAAAACAGATGAATATGGAGTACCAAAAATTTA
CTACAGTCATGATGTAACAATTACTGAAGCTGTATCAAAAGGTGCAGTAGAAGCTGCTGAAAATTTAGGAGCTAAATTAA
TAGTTTGTTGGACAAAGACTGGAAGAGCTGCTAAAATGATTAGAAAATACAACCCAACTATGCCAATTATTGCTTTAACT
GATTGTGAAGTTACTGCAAGACAATTAGCATTAGTAAGAGGAGTTAGAGCAGTTGTTGCTAAAGATTTAGATAATGCTGA
GCATTTCTTCGCAAAAGCATTAGAAGTAGCTGCATCAAATGCATCAACTACTGAAGATGAAGCATACACAGGATTTAAAA
AAGGTGATTTAGTTGTATTAGTAACAGGAATTTCTGAAACAGGAACAACTAATACATTTAAAGTTGCAAGAATAGGATAA

Protein sequence : 
MKIKMTKVVCTIGPKSEKKEVLKQLILSGMNVMRLNFSHGDFEEHGNRIKTIREISKETGKHVAILLDTKGPEIRTGSHA
EGDVKYELVEGQDFIVTTDYEFKGTPEKISVSYPNMTKDLKPGDTILIDDGLIGLEVKKIEGNEIFCKVKNSGALGQKKG
VNLPGVSVSLPALAEKDKGDLKFGCEVGVDFIAASFIRKASDVAEVRRVLDENGGEHIKIISKIENQEGIDNFDEILELS
DGIMVARGDLGVEIPVEEVPFAQKMMIKKCNAAGKPVITATQMLDSMQKNPRPTRAEAGDVANAILDGTDAVMLSGESAN
GKYPVEAVKTMATISAKTDEYGVPKIYYSHDVTITEAVSKGAVEAAENLGAKLIVCWTKTGRAAKMIRKYNPTMPIIALT
DCEVTARQLALVRGVRAVVAKDLDNAEHFFAKALEVAASNASTTEDEAYTGFKKGDLVVLVTGISETGTTNTFKVARIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-122 61
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-122 61
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-121 61
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-121 61
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 7e-59 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Smon_0413 YP_003305772.1 pyruvate kinase VFG0479 Protein 3e-122 61