Gene Information

Name : Tcur_0851 (Tcur_0851)
Accession : YP_003298479.1
Strain : Thermomonospora curvata DSM 43183
Genome accession: NC_013510
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 954358 - 955800 bp
Length : 1443 bp
Strand : +
Note : PFAM: Aldehyde Dehydrogenase; KEGG: scl:sce5007 putative aldehyde dehydrogenase (NAD(+))

DNA sequence : 
ATGAGCGACCAGATCTTTTCGTACGCGCCGGCGCCGGAGTCGGCGTCCATCGCCCGCATCAGGCCCTCCTACGGCCTGTT
CATCGACGGGGAGTGGACCGACGGCGCCGCCGAGCGCACCTTCAAGACCGTCAACCCCGCCACCGAGGAGGTGCTGGCGG
AGGTCACCGAGGCGACCGAGGAGGACGTGGACCGGGCGGTGCGCGCCGCCCGGGACGCCTACGAGCGGGTGTGGGGCCCG
ATGCCCGGCCGCGAGCGGGCCAAGTACCTGTTCCGCATCGCCCGGCTGCTGCAGGAGCGCTCCCGCGAGCTGGCCGTGCT
GGAGACCCTCGACAACGGCAAGCCGATCCGCGAGTCCCGGGATGTGGACCTGCCGCTGGTGGCCGCGCACTTCTTCTACC
ACGCCGGCTGGGCCGACAAGCTGCCGTACGCCGGATTCGGGCCCGACCCACGGCCGCTGGGGGTGGCCGCGCAGGTGATC
CCGTGGAACTTCCCGCTGCTGATGCTGGCCTGGAAGATCGCCCCCGCGCTGGCCTGCGGCAACACCGTCGTCCTCAAACC
GGCCGAGACCACCCCGCTGACCGCCCTGACGTTCGCGGAGATCTGCCGGCAGGCCGAGCTGCCGCCGGGCGTGGTCAACA
TCGTCACCGGGGCGGCCCGGACCGGGCAGGCACTGGTGCGGCACCCGGGCGTGGACAAGGTCGCCTTCACCGGCTCCACC
GAGGTCGGCAGGCAGATCGCCCGCGCCGTGGCCGGCACCCGCAAAAGGCTCACGCTGGAGCTGGGCGGCAAGGCCGCCAA
CGTGATCTTCGAGGACGCCCCGCTGGACCAGGCCGTCGAGGGCGCGATCAACGGGATCTTCTTCAACCAGGGGCAGGTGT
GCTGCGCCGGGTCCCGGCTGCTGGTGCAGGAGTCGATCGCAGGGGAGCTGCTGGAGCGGCTCAAGGCCCGGATGGCCACG
CTGCGGGTCGGGGACCCGCTGGACAAGAACACCGACGTCGGCGCGATCAACTCCGCCGGGCAGCTGGAGAAGATCCGCAC
CCTGGCGCAGGCCGGCGAACAGGAGGGCGCCATCCGCTGGTCGGCGCCGTGCGAGCTGCCGGAGCGCGGCTACTGGTTCG
CCCCGACCGTCTTCACCGGCGTGGCCGCCTCGCACCGCATCGCCCGCGAGGAGATCTTCGGCCCGGTGCTGTCGGTGCTG
ACCTTCCGCACCCCCGCCGAGGCCGTGGAGAAGGCCAACAACACCCCGTATGGGCTGTCGGCGGGGATCTGGACCGAGAA
GGGCTCACGCGTGCTGTGGATGGCCCAGCGGCTGCGCGCCGGGGTGGTGTGGGCCAACACCTTCAACAAGTTCGACCCGG
CCGCCCCGTTCGGCGGCTACAAGGAGTCGGGTTTCGGCCGCGAGGGCGGCCGTCACGGACTGGAGGCCTACCTCGATGTC
TGA

Protein sequence : 
MSDQIFSYAPAPESASIARIRPSYGLFIDGEWTDGAAERTFKTVNPATEEVLAEVTEATEEDVDRAVRAARDAYERVWGP
MPGRERAKYLFRIARLLQERSRELAVLETLDNGKPIRESRDVDLPLVAAHFFYHAGWADKLPYAGFGPDPRPLGVAAQVI
PWNFPLLMLAWKIAPALACGNTVVLKPAETTPLTALTFAEICRQAELPPGVVNIVTGAARTGQALVRHPGVDKVAFTGST
EVGRQIARAVAGTRKRLTLELGGKAANVIFEDAPLDQAVEGAINGIFFNQGQVCCAGSRLLVQESIAGELLERLKARMAT
LRVGDPLDKNTDVGAINSAGQLEKIRTLAQAGEQEGAIRWSAPCELPERGYWFAPTVFTGVAASHRIAREEIFGPVLSVL
TFRTPAEAVEKANNTPYGLSAGIWTEKGSRVLWMAQRLRAGVVWANTFNKFDPAAPFGGYKESGFGREGGRHGLEAYLDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-68 43
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-61 43
aldA ACK75580.1 aldehyde dehydrogenase Not tested VPI Protein 9e-46 41
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 1e-45 41
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 9e-46 41
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 2e-45 41
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 2e-45 41
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 1e-45 41
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 1e-45 41
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 1e-45 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-69 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-69 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-69 41
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 1e-45 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-69 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tcur_0851 YP_003298479.1 aldehyde dehydrogenase VFG0082 Protein 4e-68 43