Gene Information

Name : Tcur_4482 (Tcur_4482)
Accession : YP_003302047.1
Strain : Thermomonospora curvata DSM 43183
Genome accession: NC_013510
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 5081928 - 5083427 bp
Length : 1500 bp
Strand : -
Note : TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: afr:AFE_0480 lysyl-tRNA synthetase

DNA sequence :
GTGAGTGACAGCCAGCAGCAGGACTACGAGGACCTCCCGGAGCAGATGCGGGTGCGCCGGGAGAAGCTCGCCCGGCTCAG
GGAGAGCGGCATCGACCCCTACCCGGTGAACTTCCCCCGGACGGCCACCCTGGCCGAGGTTCGCGAGCGCTACCCCGATT
TGGAACCCGGTACCGAGACCGGCGACAAAGTCGGCGTCGCCGGACGCGTCATGCTGCTGCGCAACACCGGCAAACTGTGC
TTCGCCACCATCCGGGACGGCACCGGGCAGATCCAGGTGATGCTGTCGCAGGCCCGGGTGGGCGAGGAGGCGCTGGCCTC
CTGGAAGCGGGATGTGGACCTCGGCGACCACATCGGCGTCGAGGGCGAGGTCGTCACCTCCCGGCGCGGCGAGCTGTCGG
TCATGGCCGACCGCTACGCGATCACCTCCAAGTGCCTGCGCCCGCTGCCGGAAAAGCACGCCGGGCTGACCGACCCGGAG
GCCCGGGTGCGGCTGCGGTACGTGGACCTGATCGTCAACGACGAGGCCCGCCGCATGGCCTACCTGCGCAGCGACACCGT
GCGCGCGGTGCGGGACTTCTGGCACGAGGAGGGGTACCTCGAGGTCGAGACCCCGATGCTGCAGCCGATCCACGGCGGCG
CGGCGGCGCGTCCGTTCGTCACCCACATCAACGCCTACGACATGGACCTGTACCTGCGGATCGCCATCGAGCTGTACCTG
AAGCGGCTGGTGGTCGGCGGGATCGACAAGGTCTTCGAGATCAACCGCAACTTCCGCAACGAGGGTGCCGACTCCACCCA
CAACCCCGAGTTCACCATGCTCGAGGCCTACGGCACCTACCTGGACTACAACGACATGGCGGTGCTGACCCAGCGGATGT
ACCAGCGGGCGGTGCAGGCCGCGCTGGGCACCACCGTGGTCGTCCACAAGGGCCAGGAGGTCGATCTGGGGCTGGAGGAG
TGGCCGCGGATCACGCTGTACGGCTCGGTGTCGGAGGCGCTCGGCGAGGAGATCACCCCGCACACCCCGCTGGAGCAGGT
GCGCAAGCTGGCCGACGCCCGCCAGATCGCCTGGGATCCCAAGTGGGGGCAGGGCCGGCTGGTTCAGGAGCTGTTCGAGG
AGCTCGTCGAGCACACCTTGATCCAGCCCACCTTCGTGATGGACTACCCGCTGGAGACCTCGCCGCTGACCCGCCAGCAC
CGCTCCGAGCCGCTGCTGACCGAAAAGTGGGATCTGATCGGGTTCGGCACCGAGCTGGGCACCGCCTACAGCGAGCTGAT
CGACCCGATCGAGCAGCGCCGCCGGCTGACCGAGCAGTCGCTGCTGGCAGCCGGGGGCGATCCGGAGGCCATGCAGCTGG
ATGAGGACTTCCTGCGGGCGCTGGAGTACGGCATGCCGCCCACCGGCGGGGTGGGCGTCGGGATCGACCGGATGATCATG
GCGTTCACCGGCAAGGGCATCCGGGAGACGATCCTGTTCCCGCTCGTCAAGCCCAACTGA

Protein sequence :
MSDSQQQDYEDLPEQMRVRREKLARLRESGIDPYPVNFPRTATLAEVRERYPDLEPGTETGDKVGVAGRVMLLRNTGKLC
FATIRDGTGQIQVMLSQARVGEEALASWKRDVDLGDHIGVEGEVVTSRRGELSVMADRYAITSKCLRPLPEKHAGLTDPE
ARVRLRYVDLIVNDEARRMAYLRSDTVRAVRDFWHEEGYLEVETPMLQPIHGGAAARPFVTHINAYDMDLYLRIAIELYL
KRLVVGGIDKVFEINRNFRNEGADSTHNPEFTMLEAYGTYLDYNDMAVLTQRMYQRAVQAALGTTVVVHKGQEVDLGLEE
WPRITLYGSVSEALGEEITPHTPLEQVRKLADARQIAWDPKWGQGRLVQELFEELVEHTLIQPTFVMDYPLETSPLTRQH
RSEPLLTEKWDLIGFGTELGTAYSELIDPIEQRRRLTEQSLLAAGGDPEAMQLDEDFLRALEYGMPPTGGVGVGIDRMIM
AFTGKGIRETILFPLVKPN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 2e-122 52
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-91 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tcur_4482 YP_003302047.1 lysyl-tRNA synthetase VFG1668 Protein 1e-91 44