Gene Information

Name : Tcur_4475 (Tcur_4475)
Accession : YP_003302040.1
Strain : Thermomonospora curvata DSM 43183
Genome accession: NC_013510
Putative virulence/resistance : Virulence
Product : ATPase AAA-2 domain-containing protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 5073282 - 5075795 bp
Length : 2514 bp
Strand : -
Note : PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: CLPC; CLPC (HEAT SHOCK PROTEIN 93-V); ATP binding / ATPase

DNA sequence :
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTCGTCGTCCTGGCCCAAGAAGAGGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTTGGGCTGATCCACGAGGGGGAGGGCGTCGCCGCCAAGGCACTGGAGAGCCTGGGGA
TCAGCCTTGAGGCGGTGCGGCAGCAGGTCGAGGAGATCATCGGCCAGGGGCAGCAGGCTCCTTCTGGGCACATTCCGTTC
ACTCCGCGGGCCAAGAAGGTGCTGGAGCTGTCGCTGCGCGAGGCGCTGCAGCTCGGTCACAACTACATCGGCACCGAGCA
CATCCTTCTCGGCCTGATCCGCGAGGGCGAGGGCGTGGCCGCCCAGGTGCTGGTCAAGTTGGGGGCGGACCTGAACCGGG
TGCGCCAGCAGGTGATCCAGCTGCTGCACGGTTACACCCAGGGCAAGGAGCCCGCATCGACCGGGCCCTCGGAGTCGACC
CCGTCCACCTCGCTGGTGTTGGACCAGTTCGGCCGCAACCTGACCCAGGCCGCCCGCGAGGGCAAGCTCGACCCGGTCAT
CGGCCGGGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTGTCGCGGCGGACCAAGAACAACCCGGTGCTGGTCGGCGAGC
CCGGCGTGGGCAAGACCGCGGTGGTCGAGGGTCTGGCGCAGAAGATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAGGAC
AAGCAGCTGTACACCCTCGACCTGGGGGCGCTGGTCGCCGGGTCCCGCTACCGCGGTGACTTCGAAGAGCGGCTGAAGAA
GGTCCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACCCTGGTGGGCGCCGGCGCCG
CCGAGGGCGCCATCGACGCCGCCAGCATCCTCAAGCCGATGCTGGCCCGCGGCGAGCTGCAGACCATCGGCGCCACCACG
CTGGATGAGTACCGCAAGCACCTGGAGAAGGACGCCGCGCTGGAGCGCCGCTTCCAGCCCATCCAGGTGGCCGAGCCGTC
GCTGAGCCACACCATCGAGATCCTCAAGGGGCTGCGCGACCGGTACGAGGCGCACCACCGCGTCTCCATCACCGACGGCG
CGCTGGTGGCGGCCGCCCAGCTGGCCGACCGCTACATCTCCGACCGGTTCCTGCCCGACAAGGCCATCGACCTGATCGAC
GAGGCCGGTTCCCGCATGCGCATCCGCCGCATGACCGCCCCGCCGGACCTGCGCGAGTACGACGAGAAGATCGCCCAGGT
GCGCCGGGAGAAGGAATCGGCGATCGACGAGCAGGACTTCGAGAAGGCCGCCGCGCTGCGCGACAAGGAAAAGCAATTGC
TGGCGGCCAAGGCGCAGCGGGAGAAGGAATGGAAGGCCGGCGACATGGACGTGGTCGCCGAGGTGACCGAGGAACTGATC
GCCGAGGTCCTGGCCACGGCCACCGGCATTCCGGTCTTCAAGCTGACCGAGGAGGAGACCTCCCGGCTGCTGCGCATGGA
GGAGGAACTGCACAAGAGGGTCATCGGGCAGGAAGACGCCATCAAGGCCCTCTCGCAGTCCATCCGGCGCACCCGGGCGG
GCCTGAAGGACCCCAAGCGCCCCGGCGGCTCGTTCATCTTCGCCGGCCCCTCGGGCGTCGGTAAGACCGAGCTGTCGAAG
ACTTTGGCGGAGTTCCTCTTCGGCGACGAGGACGCGCTGATCCAGCTCGACATGAGCGAGTTCATGGAGAAGCACACCGT
CTCGCGCCTGTTCGGTTCTCCGCCGGGATATGTCGGCTATGAGGAGGGCGGCCAGCTCACCGAGAAGGTGCGCCGCAAGC
CCTTCTCCGTGGTGCTGTTCGACGAGATCGAAAAGGCGCACCCGGACATCTTCAACAGCCTGCTGCAGATTCTGGAGGAC
GGCCGGCTGACCGATGCCCAGGGCCGGACGGTGGACTTCAAGAACACCATCATCATCATGACCACCAACCTGGGCACCCG
GGACATCTCCAAGGGCCAGTCGCTGGGCTTCGCCCGTCCCGACGACCACGTCGGCGACTACGAGCGGATGAAGGCCAAGG
TCCAAGAGGAGCTCAAGCAGCACTTCCGGCCCGAGTTCCTCAACCGGGTGGACGACATCGTGGTCTTCCACCAGCTGACC
CCCAAGGAGATCATCCAGATCGTGGATCTGATGATCGCCCGGGTGGACGAGCGGCTGCGCGACCGGGACATGGGCATCGA
GCTCAAGCAGGAGGCCAAGCAGCTGCTGGCCGAGCGCGGCTACGACCCGGTGCTGGGCGCCCGTCCGCTGCGCCGCACCA
TCCAGCGCGAGATCGAAGACAGCCTGTCGGAGAAGATCCTCTACGGCGAGCTGAAGCCCGGTCAGATCGTGCTGGTGGGC
GTGGAGGGCTCCGGCGAGTCGGCCAAGTTCACCTTCACCGGCATGCCCAAGCCGTCCACCGTTCCCGACACCCCGCCGCC
GGTGGAGGGCGCGGTCAACTTCAACAAGGATTGA

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLHGYTQGKEPASTGPSEST
PSTSLVLDQFGRNLTQAAREGKLDPVIGREKEIERVMQVLSRRTKNNPVLVGEPGVGKTAVVEGLAQKIVKGEVPETLKD
KQLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LDEYRKHLEKDAALERRFQPIQVAEPSLSHTIEILKGLRDRYEAHHRVSITDGALVAAAQLADRYISDRFLPDKAIDLID
EAGSRMRIRRMTAPPDLREYDEKIAQVRREKESAIDEQDFEKAAALRDKEKQLLAAKAQREKEWKAGDMDVVAEVTEELI
AEVLATATGIPVFKLTEEETSRLLRMEEELHKRVIGQEDAIKALSQSIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSK
TLAEFLFGDEDALIQLDMSEFMEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHPDIFNSLLQILED
GRLTDAQGRTVDFKNTIIIMTTNLGTRDISKGQSLGFARPDDHVGDYERMKAKVQEELKQHFRPEFLNRVDDIVVFHQLT
PKEIIQIVDLMIARVDERLRDRDMGIELKQEAKQLLAERGYDPVLGARPLRRTIQREIEDSLSEKILYGELKPGQIVLVG
VEGSGESAKFTFTGMPKPSTVPDTPPPVEGAVNFNKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 76
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-96 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tcur_4475 YP_003302040.1 ATPase AAA-2 domain-containing protein VFG0079 Protein 0.0 62
Tcur_4475 YP_003302040.1 ATPase AAA-2 domain-containing protein VFG0080 Protein 1e-152 53