Gene Information

Name : Tcur_4247 (Tcur_4247)
Accession : YP_003301812.1
Strain : Thermomonospora curvata DSM 43183
Genome accession: NC_013510
Putative virulence/resistance : Unknown
Product : GMP synthase large subunit
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 4846871 - 4848454 bp
Length : 1584 bp
Strand : -
Note : TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: glutamine amidotransferase class-I; GMP synthase domain protein; ExsB family protein; KEGG: acp:A2cp1_1616 GMP synthase, large subunit

DNA sequence :
GTGCCCTTCGCGCAGGTCGAGCAGTCCCACGACACCGTTCTCGTCGTCGACTTCGGCGCGCAGTACGCGCAGCTGATCGC
GCGGCGCGTACGCGAGTGCAATGTGTTCAGCGAGATCGTCCCGTGCACCATGCCGGTCGAGGAGATGCTGGCCAAGCGGC
CGAAGGCGATCATCCTGTCCGGCGGGCCGGCCTCGGTGTACGAAGACGGCGCCCCGTCCGCGCCCGAGGGGCTGCTGGAG
ACCGGGGTGCCGACGCTGGGCATCTGCTACGGCCACCAGGTCATGGCGCAGGCCCTCGGCGGGGTGGTGGAGAACTCCGA
CGTCGCCGAGTACGGCCGCACCGACATCGAGGTGATCGACGGCGGGGTGCTGCTGAGCGGGCTGCCGGCCAAGCAGCCGG
TGTGGATGTCGCACCGCGACCACACCAGCGTCGCCCCCGAGGGCTTCACCGTCACCGCGCGCACCGCCGTCACCCCGGTG
GCCGCGATGGAGAACCGCGAACGCGGCCTGTACGGCGTGCAGTTCCACCCCGAGGTGGTGCACACCGAGCACGGCATGGC
GGTGCTGCGGCACTTTCTGTTCGAGGCCGCCGGCTGCCGCCCCAACTGGACCATGCTCAACATCGCCGAGGAGGCCATCG
AGGCGATCCGCGCCCAGGTCGGCGGCAAGCGCGCCATCTGCGGCCTGTCCGGCGGGGTGGACTCGGCGGTGGCCGCCGCG
CTGGTGCAGCGCGCCATCGGCTCCCGGCTGACGTGCGTCTTCGTCGATCACGGCCTGCTGCGCAAGGGCGAGGCCGAGCA
GGTGGAGAAGGACTTCGTGGCGGCCACCGGCGTCCAGCTCCACGTGGTGGACGCCCAGGAGCGGTTCCTGAGCGCGCTGG
CCGGCGTCACCGACCCCGAGACCAAGCGCAAGATCATCGGCCGGGAGTTCATCCGCGTCTTCGAACAGGCCGCCCGCGAG
ATCGTCGCCGCCCACTCCGGCGAGGACGACGACGTGGAATTCCTCGTCCAGGGCACCCTGTACCCGGATGTGGTGGAGTC
CGGCGGCGGCACCGGCGCCGCCAACATCAAGTCCCACCACAACGTCGGCGGCCTGCCCGAGGACCTGAAGTTCAAGCTGG
TCGAACCGCTGCGCACCCTGTTCAAGGACGAGGTCCGCGCCCTGGGCGAGCAGCTCGGCCTGCCTCCTGAGATCGTCTGG
CGCCATCCCTTCCCCGGCCCGGGCCTGGCCATCCGCATCATCGGCGAGGTCACCCGCGAACGCCTGGACATCCTCCGCGA
GGCCGACGCCATCGCCCGCGAGGAGCTGTCGGCCGCCGGCCTGGACCGCGACATCTGGCAGTTCCCGGTGGTGCTGCTGG
CCGACGTCCGCTCCGTCGGCGTCCAGGGCGACAGCCGCACCTACGGCCACCCCGTGGTGCTGCGCCCGGTCACCAGCGAG
GACGCCATGACCGCCGACTGGGCCCGGTTGCCGTACGACCTGCTGCAGCGCATCTCCACCCGCATCACCAACGAGGTCCG
CGAGATCAACCGCGTGGTGGTCGACATCACCAGCAAGCCCCCCGGCACCATCGAGTGGGAGTAG

Protein sequence :
MPFAQVEQSHDTVLVVDFGAQYAQLIARRVRECNVFSEIVPCTMPVEEMLAKRPKAIILSGGPASVYEDGAPSAPEGLLE
TGVPTLGICYGHQVMAQALGGVVENSDVAEYGRTDIEVIDGGVLLSGLPAKQPVWMSHRDHTSVAPEGFTVTARTAVTPV
AAMENRERGLYGVQFHPEVVHTEHGMAVLRHFLFEAAGCRPNWTMLNIAEEAIEAIRAQVGGKRAICGLSGGVDSAVAAA
LVQRAIGSRLTCVFVDHGLLRKGEAEQVEKDFVAATGVQLHVVDAQERFLSALAGVTDPETKRKIIGREFIRVFEQAARE
IVAAHSGEDDDVEFLVQGTLYPDVVESGGGTGAANIKSHHNVGGLPEDLKFKLVEPLRTLFKDEVRALGEQLGLPPEIVW
RHPFPGPGLAIRIIGEVTRERLDILREADAIAREELSAAGLDRDIWQFPVVLLADVRSVGVQGDSRTYGHPVVLRPVTSE
DAMTADWARLPYDLLQRISTRITNEVREINRVVVDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-163 70
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-134 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-134 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-134 53