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Name : Tcur_0365 (Tcur_0365) Accession : YP_003298005.1 Strain : Thermomonospora curvata DSM 43183 Genome accession: NC_013510 Putative virulence/resistance : Virulence Product : AMP-dependent synthetase and ligase Function : - COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism COG ID : COG1021 EC number : - Position : 400775 - 402349 bp Length : 1575 bp Strand : + Note : PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce3880 (2,3-dihydroxybenzoyl)adenylate synthase DNA sequence : ATGGAAGGCTTCACCCCCTGGCCGGAGGAGCTGGCCGCGCGCTACATCGCCGAGGGCTACTGGGGCGACCACGTACTGGG CGAGGTACCCCAAGGCGACCCCGACCGCGTCGCACTGGTCGCCGGAGATGAGCGCCTGACCTACGCCGAGCTGGAGCGGC GCATCGACCGCACCGCCGCCGGCCTGCACCGCCTGGGCATCCGGCGCGGCGACCGGGTGGTGCTCCAGCTGCCCAACACC GCGTCCTTCGTCATCGTCTTCCTGGCGCTGATGCGCCTGGGAGCGCCCCCGGTGCTGGCCCTGCCCGCCCACCGGCACAG CGAGATCGGCTACCTGTGCGAGCTGGCCGAGGCCAAGGCCTACATCATCCCCGACCGGCACGCCGGCTACGACTACCGCG AGCTGGCCCGCTCCCTCGGCGGCGTGGAGCACGTCATCGTCGACGGCGAGGCCGCCGAGTTCACCCCCCTGGCCGAGCTG GACGCCGACCCCATCCCGTTGGAGCGGCCCGACCCGGCCGACGTGGGCCTGTTCCTGCTGTCGGGCGGCACCACCGGCCT GCCCAAACTGATCCCCCGGACCCACCGCGACTACGTCTACAACCTGACCGCCAGCGCCGAGGTCTGCGGCTTCACCTCCG GCACCGTCTACCTGGTGGTGCTGCCGGCCGCCCACAACTTCGCCCTGGCCTGCCCCGGCCTGCTGGGCACCCTGTCGGTC GGCGGCACGGTCGTGCTGGCCCCCTCCGGCTCCCCGGACGCGGCGTTCCCGCTGATCGAACGGGAACGCGCCACCGTCTG CGCGGTCGTCCCCCCGATCGCGCTGCTGTGGCTGGACGCGGCCACCTGGTCGGAGGAGGACCTGTCGTCCCTGCAGCTGC TGCAGGTGGGCGGCGCCAAACTGGCCACGGAACCGGCCTCCAAGATCCCCGGGGTCCTCGGCTGCAAGCTGCAGCAGGTC TTCGGCATGGCCGAGGGCCTGCTCAACTACACCCGCCTGGACGACCCGCCCGAGCTGATCGAGACCACCCAGGGCCGCCC GCTGTCCCCGGCCGACGAGATCCGCGTGGTGGACCCCGACACCGGCGAGGACGTCCCCGAAGGCGAGGTCGGCGAGCTGC TCACCCGCGGCCCCTACACCCTGCGCGGCTACTACAAGGCCCCCGAGCACAACGCCCGCTCCTTCACCGCCGACGGCTTC TACCGCACCGGCGACCTGGTGCGGCGGCTGCCGTCCGGCCACCTGGTGGTGGAGGGGCGCCACAAGGACCAGATCAACCG GGGCGGCGAGAAGATCGCCGCCGAGGAGCTGGAAGGCCACCTGATCGCCCACCCGGCCGTCCACGACGCGGCGGTCGTCG GCGTGCCCGACCCGGTCATGGGCGAACGCACCTGCGCGTTCCTCGTCGCCCGCGGCACCCCGCCCACCCTGCGGGAGGTG AAGGAGTTCCTGCGCGACCGCGGAGTGGCCGACTACAAGTGGCCCGACCGCATCGAAGTGGTCGACGCCTTCCCCCGCAC CCCCGTCGGCAAGATCAGCAAGAAGGCGCTCCTCGCCATGCTGGACAAGGCCTAG Protein sequence : MEGFTPWPEELAARYIAEGYWGDHVLGEVPQGDPDRVALVAGDERLTYAELERRIDRTAAGLHRLGIRRGDRVVLQLPNT ASFVIVFLALMRLGAPPVLALPAHRHSEIGYLCELAEAKAYIIPDRHAGYDYRELARSLGGVEHVIVDGEAAEFTPLAEL DADPIPLERPDPADVGLFLLSGGTTGLPKLIPRTHRDYVYNLTASAEVCGFTSGTVYLVVLPAAHNFALACPGLLGTLSV GGTVVLAPSGSPDAAFPLIERERATVCAVVPPIALLWLDAATWSEEDLSSLQLLQVGGAKLATEPASKIPGVLGCKLQQV FGMAEGLLNYTRLDDPPELIETTQGRPLSPADEIRVVDPDTGEDVPEGEVGELLTRGPYTLRGYYKAPEHNARSFTADGF YRTGDLVRRLPSGHLVVEGRHKDQINRGGEKIAAEELEGHLIAHPAVHDAAVVGVPDPVMGERTCAFLVARGTPPTLREV KEFLRDRGVADYKWPDRIEVVDAFPRTPVGKISKKALLAMLDKA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ybtE | AAA93464.1 | yersiniabactin 2,3-dihydoxybenzoate-AMP ligase | Virulence | HPI | Protein | 4e-103 | 53 |
| ybtE | YP_853079.1 | yersiniabactin siderophore biosynthetic protein | Virulence | PAI IV APEC-O1 | Protein | 5e-103 | 53 |
| irp5 | YP_002346898.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 5e-103 | 53 |
| ybtE | NP_669710.1 | salicyl-AMP ligase | Virulence | HPI | Protein | 5e-103 | 53 |
| ybtE | NP_993003.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 5e-103 | 53 |
| ybtE | YP_070120.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 5e-103 | 53 |
| ybtE | CAA21394.1 | - | Virulence | HPI | Protein | 5e-103 | 53 |
| irp5 | YP_001006819.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 4e-102 | 52 |
| irp5 | CAA73130.1 | Irp5 protein | Virulence | HPI | Protein | 3e-102 | 52 |
| irp2E | YP_005134497.1 | siderophore biosynthetic protein | Virulence | Not named | Protein | 5e-71 | 44 |
| irp2E | YP_005163485.1 | siderophore biosynthetic protein | Virulence | Not named | Protein | 6e-71 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Tcur_0365 | YP_003298005.1 | AMP-dependent synthetase and ligase | VFG0168 | Protein | 2e-121 | 57 |
| Tcur_0365 | YP_003298005.1 | AMP-dependent synthetase and ligase | VFG1817 | Protein | 5e-109 | 52 |
| Tcur_0365 | YP_003298005.1 | AMP-dependent synthetase and ligase | VFG0932 | Protein | 5e-99 | 48 |
