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Name : Tcur_3204 (Tcur_3204) Accession : YP_003300783.1 Strain : Thermomonospora curvata DSM 43183 Genome accession: NC_013510 Putative virulence/resistance : Virulence Product : urease subunit alpha Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0804 EC number : 3.5.1.5 Position : 3705465 - 3707189 bp Length : 1725 bp Strand : + Note : KEGG: met:M446_2211 urease, alpha subunit; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein; Amidohydrolase 3 DNA sequence : ATGACTGAACTGTCGCGCGCCCGCTATGCGGCGCTGTTCGGCCCGACCACGGGCGACCGCATCCGCCTGGCCGACACCAA CCTGTTCATCGAGGTCACCGAGGACCGTTCCATGGGAGCGGCCGGGGCCGGCGATGAGGCGGTGTTCGGCGGCGGCAAGG TGATCCGCGAATCGATGGGCCAGGCCCGCACCACCCGCGCCGAGGGCGCCGTGGACCTGGTGATCACCGGCGCGGTGGTG CTGGACTACTGGGGGATCGTCAAGGCGGACGTGGGCGTCCGCGACGGACGGATCGTGGCGCTGGGCAAGGCCGGCAACCC CGACACCATGGACGGGGTGCACCCGGACCTGGTGATCGGGCCGTCCACCGAGGTGCTGGCCGGCAACGGCAAGATCCTGA CCGCCGGGGCGATCGACTCCCACGTGCACCTGATCTGCCCGCAGCTGGTGGAAGAGGCGCTGGGCGCCGGGGTGACCACG CTGCTGGGCGGCGGCACCGGCCCGGCCGAGGGCACCAAGGCCACCACGGTGACCGGCGCCTGGTACCTGCACCGGATGCT GGAGGCGCTGGATGTCTGGCCGGTCAACGTGGCGCTGCTGGGCAAGGGCAACACCGTCTCCTCCGAGGCGCTGTGGGAGC AGCTGCGCGCCGGGGCCTGCGGGTTCAAGCTGCACGAGGACTGGGGGTCCACCCCGGCGGCGATCGACGCCTGCCTGAAG GTCGCCGACGCCTCCGGCGTGCAGGTGGCCCTGCACAGCGACACCCTGAATGAGGCCGGGTACGTGGAGTCCACCCTGGA GGCGATCGCCGGCCGGTCGATCCACGCCTACCACACCGAGGGCGCCGGCGGCGGGCACGCCCCCGACATCATCACCGTCG CCGCGCACCCCAACGTGCTGCCGTCCTCGACCAACCCGACCCGCCCGCACACCGTCAACACCCTGGACGAGCACCTGGAC ATGCTGATGGTGTGCCACCACCTCAACCCGGCGGTGCCCGAGGACCTGGCGTTCGCCGAGTCCCGGATCCGCCCCACCAC CATGGCGGCCGAGGACATCCTGCACGACCTGGGCGCCATCTCGATGATCGGCTCGGACTCCCAGGCGATGGGCCGGATCG GGGAGACCGTCATCCGCACCTGGCAGACCGCGCACGTGATGAAGGAGCGCCGCGGCTCCCTGCCGGGCGACGGCGCCGAG CCCGCCGACAACCTGCGGGCCCGCCGCTATGTGGCCAAGTACACCATCAACCCGGCCATCGCCCACGGCCTGGACGACCT GGTCGGGTCGGTGGAGCCGGGCAAGCTGGCCGACCTGGTGCTGTGGGAGCCGGCGTTCTTCGGGGTGCGCCCGTCGGTGG TGCTCAAGGGCGGGGTGATCGCCTGGGCGGCGATGGGCGACGCCAACGCCTCCATCCCCACCCCGCAGCCGGTGCTGCCC CGTCCGATGTTCGGCGCCGCGCCCGCGGCGGCCGCCGCCACCTCGGTGCACTTCGTCGCCCCGGCGGCGATCGAGGACGG CCTGGCCGGCAAGATCGCGGTGAACCGCCCGCTGGTGCCGGTCAAGAACACCCGCCGCCTGGGCAAGGCCGACCTGCCGC TCAACGACGCGCTGCCGGCCATCGAGGTGGACCCGGACACCTTCACCGTCACCATCGACGGCGAGGAGGTCGAGCCCGCC CCGGCCGCCGAGCTGCCGATGGCCCAGCGCTACTTCCTGTTCTGA Protein sequence : MTELSRARYAALFGPTTGDRIRLADTNLFIEVTEDRSMGAAGAGDEAVFGGGKVIRESMGQARTTRAEGAVDLVITGAVV LDYWGIVKADVGVRDGRIVALGKAGNPDTMDGVHPDLVIGPSTEVLAGNGKILTAGAIDSHVHLICPQLVEEALGAGVTT LLGGGTGPAEGTKATTVTGAWYLHRMLEALDVWPVNVALLGKGNTVSSEALWEQLRAGACGFKLHEDWGSTPAAIDACLK VADASGVQVALHSDTLNEAGYVESTLEAIAGRSIHAYHTEGAGGGHAPDIITVAAHPNVLPSSTNPTRPHTVNTLDEHLD MLMVCHHLNPAVPEDLAFAESRIRPTTMAAEDILHDLGAISMIGSDSQAMGRIGETVIRTWQTAHVMKERRGSLPGDGAE PADNLRARRYVAKYTINPAIAHGLDDLVGSVEPGKLADLVLWEPAFFGVRPSVVLKGGVIAWAAMGDANASIPTPQPVLP RPMFGAAPAAAAATSVHFVAPAAIEDGLAGKIAVNRPLVPVKNTRRLGKADLPLNDALPAIEVDPDTFTVTIDGEEVEPA PAAELPMAQRYFLF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ureC | NP_286680.1 | urease subunit alpha | Virulence | TAI | Protein | 1e-148 | 61 |
| ureC | NP_287088.1 | urease subunit alpha | Not tested | TAI | Protein | 1e-148 | 61 |
| ureC | YP_005684266.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 1e-144 | 59 |
| ureC | YP_005682174.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 4e-145 | 59 |
| ureC | YP_003784325.1 | urease subunit alpha | Not tested | PiCp 7 | Protein | 4e-145 | 59 |
| ureC | YP_005686358.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 4e-145 | 59 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Tcur_3204 | YP_003300783.1 | urease subunit alpha | VFG0270 | Protein | 3e-130 | 55 |
