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Name : Tcur_2862 (Tcur_2862) Accession : YP_003300445.1 Strain : Thermomonospora curvata DSM 43183 Genome accession: NC_013510 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : 2.7.1.40 Position : 3337796 - 3339226 bp Length : 1431 bp Strand : - Note : KEGG: mxa:MXAN_6299 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta DNA sequence : GTGAACCGTCGAGCGAAGATAGTCAGTACCATCGGACCGGCCTGCTCCAGCGAGGAACAGATCTACGCCCTCGTCAAAGC CGGCATCGACGTCGCCCGCCTCAACATGAGCCACGGCGACCACGCCACCCACGAGGCCGTCTACCACCGCATCCGCGCCG CCTCCGACGCCACCGGACACGGCGTGGGCATCCTCGCCGACCTGCAAGGACCCAAGATCCGCATCGGCCGCTTCGCCGAG GGCCCCGTCCGCCTCTCCTTCGACGACGAGTTCACCATCACCACCGAGGACGTCCCCGGCAACCACAAGCAGGTCTCCAC CTCCTACAAGGGACTCCCCGGCGACGTCACCGTCGGCGACACCATCCTCATCGACGACGGCCGCATCGCCCTCGCCGTCA CCGACGTCGACGGCCCCCGCGTCCACACCCGCGTCATGGTCGGCGGCGTCCTGTCCGACAACAAAGGACTCAACCTTCCC GGCGTCCCCGTCAGCGTCCCCGCCCTCACCGAAAAAGACGAAGCAGACCTGCGCTGGGCGCTGCGCCTGGGCATCGACAT GATCGCCCTGTCCTTCGTCCGCAGCCCCGCCGACGCCGAAGTCTGCTACCGCATCATGGAAGAGGAGGGCGTCCGCGTCC CCCTCATCGCCAAAATCGAAAAACCCCAGGCCGTCGAGGCGCTCCCCGAAATCGTCGCCGCCTTCGATGGCATCATGGTC GCCCGCGGGGACCTCGGCGTCGAACTGCCCCTCGAACAAGTCCCCATCGTCCAGAAACGAGCCATCGAGCTGTGCCGCGA AAAGGCCCGCCCCGTCATCGTGGCCACCCAGATGCTCGAATCCATGATCTCCTCCCCCCGCCCCACCCGCGCCGAGGCCT CCGACGTCGCCAACGCCATCTACGAGGGCGCCGACGCCGTCATGCTCTCCGGCGAGACCAGCGTCGGCCAATACCCCGTC GAAGCGGTCCAGACCATGAGCCGCATCGCCATCGCCACCGAACGCGACACCCTGCGCGCCGTCCACTCCCTGGACCGCAA GCCCGAAACCGTCGGCGGCGCCATCGCCCGCGCCGCCGCCGAAGTCGGCGCCATCGTCGGAGCCAAGGCCCTGGTCGCCT TCACCATGTCCGGGGAGACCGCCCGCCGCCTGGCCCGCTACCGCTCACCCATCCCGTTGCTGGCCTTCACCACCGTTCAG GCCACCCGCAGCCAGCTCTCCCTGGTCTGGGGCGTGGAGACCTTCATCGTCCCCCATGTCGACCACACCGACGACATGGT CCGCCAGGTCGACCAGGCCCTGCTCGAAATCGGCCGCTGCCAAAAGGGCGACCGCGTCGTCATCGTCGCCGGCTCGCCCC CCGGCACCCCCGGCTCCACCAACGCCCTGCGCGTCCACCGCATCGGCGACGCCATCGGCATGCGCCACTGA Protein sequence : MNRRAKIVSTIGPACSSEEQIYALVKAGIDVARLNMSHGDHATHEAVYHRIRAASDATGHGVGILADLQGPKIRIGRFAE GPVRLSFDDEFTITTEDVPGNHKQVSTSYKGLPGDVTVGDTILIDDGRIALAVTDVDGPRVHTRVMVGGVLSDNKGLNLP GVPVSVPALTEKDEADLRWALRLGIDMIALSFVRSPADAEVCYRIMEEEGVRVPLIAKIEKPQAVEALPEIVAAFDGIMV ARGDLGVELPLEQVPIVQKRAIELCREKARPVIVATQMLESMISSPRPTRAEASDVANAIYEGADAVMLSGETSVGQYPV EAVQTMSRIAIATERDTLRAVHSLDRKPETVGGAIARAAAEVGAIVGAKALVAFTMSGETARRLARYRSPIPLLAFTTVQ ATRSQLSLVWGVETFIVPHVDHTDDMVRQVDQALLEIGRCQKGDRVVIVAGSPPGTPGSTNALRVHRIGDAIGMRH |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 5e-72 | 43 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 1e-71 | 43 |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 5e-72 | 43 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 5e-72 | 43 |
| pykA | NP_273151.1 | pyruvate kinase | Not tested | IHT-A | Protein | 2e-62 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Tcur_2862 | YP_003300445.1 | pyruvate kinase | VFG0479 | Protein | 2e-72 | 43 |
