Gene Information

Name : Tcur_0234 (Tcur_0234)
Accession : YP_003297877.1
Strain : Thermomonospora curvata DSM 43183
Genome accession: NC_013510
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 257648 - 260239 bp
Length : 2592 bp
Strand : -
Note : KEGG: acp:A2cp1_0414 ATP-dependent chaperone ClpB; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase

DNA sequence :
GTGGACTACAAGCTGACACGAAAAAGCCAGGAGGCGGTGTCGATCGCGGTCCGCCGGGCCGCGGCCGAAGGCCACCCCCA
GGTTGAACCGTTGCATTTGCTGGTGGCGCTGCTGGCGCTGCCGGAGGGCACCGCGGTCCCGCTGCTGGAGGCGGTCGGGG
CCGACTGGCAGGCGGTGCGCAGCGCCGCCGAGGAACGGCTGGCCCGGCTGCCCAGGGCGGCCGGTTCGACGGTGAGCAGC
CCGCAGATGTCGCGGCAGCTCATCATGGCGATGAACACCGCCGGCAACCGCGCCCGGCAGATGGAGGACGAGTACGTCTC
CACCGAGCACCTGCTGGTGGGGCTGGCCGCCGACGGCGGTGAGGCCGCCCAGGTGCTGCGCGAGGCCGGGGCCACCCCGC
AGGCGCTGCTGGAGGCGTTCGAGAAGGTGCGCGGGCACGCCCGGGTCACCAGCGAGGACCCCGAGGGCACCTACCAGGCG
CTGGAGAAGTACGGCGTCGACCTGACCGCCCGGGCCCGCGAGGGCAAGCTGGACCCGGTGATCGGCCGGGACACCGAGAT
CCGGCGGGTGGTGCAGGTGCTGGCCCGCCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCGGCAAGACCG
CCGTGGTGGAGGGGCTGGCCCAGCGGATCGTGGCCGGGGACGTGCCCGAGTCGCTCAAGGGCAAGCGCCTGGTGGCGCTG
GACCTGGGCGCCATGGTGGCCGGGGCCAAGTACCGCGGTGAGTTCGAAGAGCGGCTCAAGGCCGTCCTGAACGAGATCAA
AAGCAGCGAGGGCCAGGTCATCACCTTCATCGACGAGCTGCACACCGTGGTCGGGGCCGGTGCCGCCGAGGGCGCCATGG
ACGCCGGCAACATGCTCAAGCCGATGCTGGCGCGCGGCGAACTGCGCATGATCGGCGCGACCACGCTGGATGAGTACCGC
GAGCGGATCGAAAAGGACCCCGCCCTGGAGCGGCGCTTCCAGCAGGTGTTCGTGGGCGAGCCGTCGGTGGAGGACACCAT
CGCGATCCTGCGCGGGCTCAAGGGCCGCTACGAGGCGCACCACCAGGTGCAGATCTCGGACGCGGCGCTGGTGGCCGCCG
CGGCGCTGTCGGACCGCTACATCACCGCCCGGTTCCTGCCGGACAAGGCCATCGACCTGGTGGACGAGGCCGCCTCCCGG
CTGCGCATGGAGATCGACTCCCGTCCGGTGGAGATCGACGAGCTGCAGCGCACGGTGGACCGGATGCGCATGGAGGAGCT
GGCGCTGGCCAAGGAGTCCGACGAGGCCTCCAAGCAGCGCCTGGAGCGGCTGCGCCGCGACCTGGCCGACAAGAACGAGC
AGCTCAACGCGCTGATCGCGCGCTGGGAGCAGGAGAAGGCCGGGCTGAACCGGGTCGGTGAGCTCAAAAAGCGCATCGAC
CAGCTGCGCGGGGAGGCCGAGCGCGCCCAGCGCGACGGCGACCTGGAGACCAGCGCCCGCATCACCTACGGGGAGATCCC
GGCGCTGGAGAAGGAGCTGAAGGCCGCCGCCGAGCAGGCCGAGAAGCGGGACGCGATGGTCAAGGAGGAGGTCGGCCCGG
ACGATGTGGCCGATGTGGTGGCCTCCTGGACCGGCATCCCGGCCGGGCGGCTGCTGGAGGGCGAGACCGCCAAGCTGCTG
CGCATGGAGGAGGAGATCGGCCGCCGGCTGGTCGGGCAGACCCAGGCGGTCAAGGCGGTCTCCGACGCGGTGCGCCGGGC
CCGGGCCGGGGTCTCCGACCCCGACCGTCCCACCGGGTCGTTCCTGTTCCTCGGCCCCACCGGGGTGGGCAAGACCGAGC
TGGCCAAGGCGCTGGCGGAGTTCCTGTTCGACGACGAGCGCGCCATGGTGCGCATCGACATGTCGGAGTACTCCGAAAAG
CACAGCGTGGCCCGGCTGGTGGGCGCCCCGCCCGGCTATGTGGGCTATGAGGAGGGCGGTCAGCTCACCGAGGCCGTGCG
GCGCCGCCCCTACTGCGTGGTGCTGCTGGACGAGGTGGAAAAGGCCCACCCGGAGGTTTTCGACATCCTGCTGCAGGTCC
TCGACGACGGCCGGCTGACCGACGGCCAGGGCCGCACCGTGGACTTCCGCAACACCATCCTGATCATGACCTCCAACCTG
GGCTCGCAGTACCTGGTGGACCCCACCTTGAGCAGCGAGGCCAAGCGGGAGTCGGTGATGAACACGGTGCGGGCCTCGTT
CAAGCCGGAGTTCCTCAACCGGCTGGACGACATCATCCTGTTCGAGGCGCTGTCCACCGAGGACCTGACCCGCATCGTGG
ACCTGCAGGTCGCCCGGCTGGCCAAGCGCCTGGCCGACCGGAGGCTGAAGCTGACGGTCACCGACGCGGCCCGCGAGTGG
CTGGCGCTGACCGGCTACGACCCGCTGTACGGCGCCCGCCCGCTGCGCCGCCTGGTGCAGACCGCCATCGGCGACCAGCT
GGCCCGCGAACTGCTGGCCGGCACGATCGGCGACGGCGATGAGGTCGTGGTGGATCTGGACGAGGCCGCCGACCGCCTCA
CCGTCAAGCCCGCCGCTTCGCTCACCAAGTAA

Protein sequence :
MDYKLTRKSQEAVSIAVRRAAAEGHPQVEPLHLLVALLALPEGTAVPLLEAVGADWQAVRSAAEERLARLPRAAGSTVSS
PQMSRQLIMAMNTAGNRARQMEDEYVSTEHLLVGLAADGGEAAQVLREAGATPQALLEAFEKVRGHARVTSEDPEGTYQA
LEKYGVDLTARAREGKLDPVIGRDTEIRRVVQVLARRTKNNPVLIGEPGVGKTAVVEGLAQRIVAGDVPESLKGKRLVAL
DLGAMVAGAKYRGEFEERLKAVLNEIKSSEGQVITFIDELHTVVGAGAAEGAMDAGNMLKPMLARGELRMIGATTLDEYR
ERIEKDPALERRFQQVFVGEPSVEDTIAILRGLKGRYEAHHQVQISDAALVAAAALSDRYITARFLPDKAIDLVDEAASR
LRMEIDSRPVEIDELQRTVDRMRMEELALAKESDEASKQRLERLRRDLADKNEQLNALIARWEQEKAGLNRVGELKKRID
QLRGEAERAQRDGDLETSARITYGEIPALEKELKAAAEQAEKRDAMVKEEVGPDDVADVVASWTGIPAGRLLEGETAKLL
RMEEEIGRRLVGQTQAVKAVSDAVRRARAGVSDPDRPTGSFLFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYSEK
HSVARLVGAPPGYVGYEEGGQLTEAVRRRPYCVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTILIMTSNL
GSQYLVDPTLSSEAKRESVMNTVRASFKPEFLNRLDDIILFEALSTEDLTRIVDLQVARLAKRLADRRLKLTVTDAAREW
LALTGYDPLYGARPLRRLVQTAIGDQLARELLAGTIGDGDEVVVDLDEAADRLTVKPAASLTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 6e-143 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tcur_0234 YP_003297877.1 ATP-dependent chaperone ClpB VFG2076 Protein 2e-113 46
Tcur_0234 YP_003297877.1 ATP-dependent chaperone ClpB VFG2084 Protein 3e-103 43